Results 71 to 80 of about 64,784 (295)

Thyroid Hormone Levels in Patients with Head and Neck Cancer Undergoing Radiochemotherapy: A Retrospective Study [PDF]

Journal of Clinical and Diagnostic Research
Introduction: Head and Neck Cancers (HNCs) are a common type of cancer, affecting approximately 6% of the global cancer burden. The treatment of HNC often involves Radiochemotherapy (RCT), which can have adverse effects on the thyroid gland.
Nidhi Rohan Purandare, Meenakshi, Shilpa Jain, Neeti Patel, Sarita A Shinde   +4 more
doaj   +1 more source

Eosinophil/Monocyte Ratio Combined With Serum Thyroid Hormone for Distinguishing Graves' Disease and Subacute Thyroiditis

Frontiers in Endocrinology, 2020
Background: Thyrotoxicosis is commonly classified into several entities according to different etiologies. Identifying the causes of thyroid dysfunction is critical for the subsequent selection of treatment.
Yongbin Hu, Diyi Zhou, Jiawei Chen, Pengfei Shan   +3 more
doaj   +1 more source

Osteogenic Small Molecule FK506 for Enhanced Bone Formation in a Rabbit Ankle Fusion Model

Journal of Orthopaedic Research, EarlyView.
ABSTRACT Non‐union remains a significant complication following ankle fusion procedures, underscoring the need for effective osteogenic adjuvants to improve boney healing and fusion outcomes. This study investigates the osteogenic potential of FK506 (Tacrolimus), both in vitro and in vivo, for enhanced ankle fusion.
Nicholas Huffman, Amogh Magesh, Hanna Solomon, Caroline Dingler, Sreedhara Sangadala, Jay M. Patel, Jason T. Bariteau   +6 more
wiley   +1 more source

Neurobehavioral function and low-level exposure to brominated flame retardants in adolescents : a cross-sectional study [PDF]

, 2012
Background: Animal and in vitro studies demonstrated a neurotoxic potential of brominated flame retardants, a group of chemicals used in many household and commercial products to prevent fire.
Baeyens, Willy, Bruckers, Liesbeth, Covaci, Adrian, Croes, Kim, Den Hond, Elly, Dirtu, Alin C, Kiciński, Michał, Nawrot, Tim S, Nelen, Vera, Schoeters, Greet, Sioen, Isabelle, Van Larebeke, Nicolas, Viaene, Mineke K   +12 more
core   +1 more source

Transcriptomic Signatures of Monocyte‐Derived Macrophages Associate With Androgen Receptor Pathway Inhibitor Progression in Prostate Cancer

The Prostate, EarlyView.
ABSTRACT Background Androgen receptor pathway inhibitors (ARPIs) have significantly improved clinical outcomes for patients with metastatic prostate cancer (PC) but acquired ARPI resistance remains universal. Maximizing ARPI treatment duration is crucial to optimal clinical outcomes, but current clinical tools to detect acquired ARPI resistance ...
Marina Nasrin Sharifi, Erika Heninger, Matthew Leeson Bootsma, Emma Elizabeth Recchia, Matthew Thomas Breneman, Amy Kristine Taylor, Shuang George Zhao, Aaron Matthew LeBeau, David Kosoff   +8 more
wiley   +1 more source

PRMT5:MEP50 Are Mediators of Treatment‐Induced Neuroendocrine Differentiation in Prostate Cancer

The Prostate, EarlyView.
ABSTRACT Background Neuroendocrine prostate cancer (NEPC) is a lethal subtype of prostate cancer responsible for an estimated 20%–30% of castration‐resistant prostate cancer (CRPC) deaths. While NEPC can arise spontaneously, the majority of these cases emerge as treatment‐induced NEPC (tNEPC).
Hye Seung Nam, Andrew Michael Asberry, Xuehong Deng, Sheng Liu, Jiaoti Huang, Chang‐Deng Hu, Jun Wan, Michael K. Wendt   +7 more
wiley   +1 more source

Thyroid-hormone therapy and thyroid cancer: a reassessment. [PDF]

, 2005
Experimental studies and clinical data have demonstrated that thyroid-cell proliferation is dependent on thyroid-stimulating hormone (TSH), thereby providing the rationale for TSH suppression as a treatment for differentiated thyroid cancer.
BIONDI, BERNADETTE, Filetti S, Schlumberger M.   +2 more
core  

Modeling Adipokine and Insulin‐Mediated Crosstalk Between Adipocytes and Beta Cells Using Flow‐Enabled Microfluidics

Small, EarlyView.
A microfluidic system with a µTesla pump is developed to model adipocyte–beta cell crosstalk under flow. Elevated glucose and insulin enhanced adipocyte secretion of IL‐6, TNF‐α, and adiponectin, while IL‐6 stimulated beta‐cell insulin secretion. This feed‐forward loop mimics obesity‐driven beta cell dysfunction, offering new insights into Type 2 ...
Mohamad Orabi, Mehdi Sh Yeganeh, Tae‐Hwa Chun, Joe Fujiou Lo   +3 more
wiley   +1 more source

Pituitary apoplexy is associated with concurrent or subsequent diagnosis of human immunodeficiency virus

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
Abstract Objective Pituitary apoplexy (PA) is a rare condition caused by hemorrhage or infarction of the pituitary gland with associated risk of cranial neuropathies, endocrinopathies, and even death. Human immunodeficiency virus (HIV) has been shown to have some association with pituitary apoplexy, however, large‐scale studies have not been performed.
Jennifer E. Douglas, Mandy K. Salmon, Rijul S. Kshirsagar, Jacob G. Eide, Caitlin White, Julia Kharlip, Christina Jackson, John Y. K. Lee, Daniel Yoshor, Michael A. Kohanski, James N. Palmer, Nithin D. Adappa   +11 more
wiley   +1 more source

Iodine and selenium intakes and status and thyroid function in midlife women with low bread intakes in New Zealand

Nutrition &Dietetics, EarlyView.
Abstract Aims Iodine and selenium are important nutrients for thyroid function; however, the New Zealand food supply is generally low in both minerals. Bread can be a good source of these minerals; although the popularity of lower carbohydrate diets means some people avoid bread. This study aimed to investigate the effect of low bread intakes on iodine
Jaime Berger, Jacqueline Finlayson, Pamela R. von Hurst, Louise Brough   +3 more
wiley   +1 more source