Results 91 to 100 of about 381,907 (293)
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Applied SciencesOne of the promising strategies for the improvement of the resistance characteristics and energy efficiency of a ship is trim optimization. Most of the studies conducted so far regarding trim optimization deal with unrestricted water.
Ivana Martić +3 more
doaj +1 more source
Tumor Biology, 2017 Osteosarcoma is one of the most lethal malignancies, and the prognosis remains dismal due to the paucity of effective therapeutic targets. Bmi-1 and TRIM-14 are associated with the initiation and progression of osteosarcoma, which could promote ...
Gui-Hua Yu +4 more
doaj +1 more source
FEBS Open Bio, EarlyView.Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid +3 more
wiley +1 more source
Micromachines, 2018 Heat dissipation has become an important issue due to the miniaturization of various electronic devices. Various methods such as spray and nozzle coolers, heat sinks and so on are used for heat dissipation.
Jae-Hee Kim +2 more
doaj +1 more source
Trim Flight Conditions for a Low-Boom Aircraft Design Under Uncertainty [PDF]
The purpose of this paper is to investigate the noise generation of a low-boom aircraft design in flight trim conditions under uncertainty. The deflection of control surfaces to maintain a trimmed flight state has the potential to change the perceived ...
Phillips, Ben D, West, Thomas K., IV
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FEBS Open Bio, EarlyView.Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold +11 more
wiley +1 more source
Tank Tests of a Model of the NC Flying-boat Hull - N.A.C.A. Model 44 [PDF]
A 1/7.06 full-size model of the NC-type hull was tested in the N.A.C.A. tank by both the general method and the specific or free-to-trim method. The results of the tests are given in curves plotted as non dimensional coefficients and are compared with ...
Bell, Joe W
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FEBS Open Bio, EarlyView.The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida +6 more
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MOD-0 wind turbine dynamics test correlations [PDF]
, 1981 The behavior of the teetered, downwind, free yaw, MOD-0 wind turbine, as represented by NASA dynamic test data, was used to support confidence in the Hamilton Standard computer code simulations.
Brooks, B. M.
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