Results 11 to 20 of about 454,552 (336)

TRIM proteins in hepatocellular carcinoma

open access: yesJournal of Biomedical Science, 2022
The tripartite motif (TRIM) protein family is a highly conserved group of E3 ligases with 77 members known in the human, most of which consist of a RING-finger domain, one or two B-box domains, and a coiled-coil domain.
Kan Lu   +5 more
doaj   +2 more sources

TRIM family contribute to tumorigenesis, cancer development, and drug resistance

open access: yesExperimental Hematology & Oncology, 2022
The tripartite-motif (TRIM) family represents one of the largest classes of putative single protein RING-finger E3 ubiquitin ligases. TRIM family is involved in a variety of cellular signaling transductions and biological processes.
Ning Huang   +6 more
doaj   +2 more sources

TRIM proteins [PDF]

open access: yesCurrent Biology, 2019
Vunjak and Versteeg introduce the TRIM family of post-translational modifiers and the roles of these proteins in viral restriction, immune signaling and autophagy.
Vunjak, Milica, Versteeg, Gijs
openaire   +4 more sources

Comprehensive Analysis of the Prognostic Values of the TRIM Family in Hepatocellular Carcinoma

open access: yesFrontiers in Oncology, 2021
BackgroundAccumulating studies have demonstrated the abnormal expressions and prognostic values of certain members of the tripartite motif (TRIM) family in diverse cancers.
Weiyu Dai   +19 more
doaj   +2 more sources

Degradation of endogenous proteins and generation of a null-like phenotype in zebrafish using Trim-Away technology

open access: yesGenome Biology, 2019
Trim-Away is a recent technique to rapidly deplete a protein from any cell type. Guided by antibodies, TRIM21 selects proteins for destruction. However, the applicability of this method in model organisms has not been investigated.
Xiao Chen   +7 more
doaj   +2 more sources

Longitudinal Trim and Dynamic Stability Analysis of a Seagull-Based Model

open access: yesApplied Sciences, 2022
Understanding the mechanisms of trim and flight stability in birds is critical to guide the design of bionic micro air vehicles. The complex movements (plunging, sweeping, twisting) and morphing of wings always keeps the flapping flight of birds in ...
Dong Xue, Bifeng Song, Wenping Song
doaj   +1 more source

Trim-Away ubiquitinates and degrades lysine-less and N-terminally acetylated substrates

open access: yesNature Communications, 2023
TRIM proteins are the largest family of E3 ligases in mammals. They include the intracellular antibody receptor TRIM21, which is responsible for mediating targeted protein degradation during Trim-Away.
L. Kiss   +11 more
semanticscholar   +1 more source

Thecomposition of semi finished inventories at a solid board plant [PDF]

open access: yes, 2001
A solid board factory produces rectangular sheets of cardboard in two different formats, namely large formats and small formats. The production process consists of two stages separated by an inventory point.
Gaalman, Gerard J.C.,   +2 more
core   +7 more sources

TRIM family proteins: roles in proteostasis and neurodegenerative diseases

open access: yesOpen Biology, 2022
Neurodegenerative diseases (NDs) are a diverse group of disorders characterized by the progressive degeneration of the structure and function of the central or peripheral nervous systems. One of the major features of NDs, such as Alzheimer's disease (AD),
Yan Zhu   +4 more
semanticscholar   +1 more source

TRiM: Enhancing Processor-Memory Interfaces with Scalable Tensor Reduction in Memory

open access: yesMicro, 2021
Personalized recommendation systems are gaining significant traction due to their industrial importance. An important building block of recommendation systems consists of the embedding layers, which exhibit a highly memory-intensive characteristic.
Jaehyun Park   +5 more
semanticscholar   +1 more source

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