Results 51 to 60 of about 381,907 (293)
Human Genomics, 2022 Background The tripartite motif (TRIM) proteins function as important regulators in innate immunity, tumorigenesis, cell differentiation and ontogenetic development.
Yueying Gao +10 more
doaj +1 more source
A 65-nm CMOS Temperature-Compensated Mobility-Based Frequency reference for wireless sensor networks [PDF]
, 2010 For the first time, a temperature-compensated CMOS frequency reference based on the electron mobility in a MOS transistor is presented. Over the temperature range from -55°C to 125 °C, its frequency spread is less than ±0.5% after a two-point trim and ...
Breems, Lucien +5 more
core +2 more sources
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
The Roles of TRIMs in Antiviral Innate Immune Signaling
Frontiers in Cellular and Infection Microbiology, 2021 The Tripartite motif (TRIM) protein family, which contains over 80 members in human sapiens, is the largest subfamily of the RING-type E3 ubiquitin ligase family.
Zhou Shen +8 more
doaj +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
, 2014 Btrim is a fast and lightweight software to trim adapters and low quality regions in reads from ultra high-throughput next-generation sequencing machines. It also can reliably identify barcodes and assign the reads to the original samples.
Kong, Yong
core +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
TRIM family contribute to tumorigenesis, cancer development, and drug resistance
Experimental Hematology & Oncology, 2022 The tripartite-motif (TRIM) family represents one of the largest classes of putative single protein RING-finger E3 ubiquitin ligases. TRIM family is involved in a variety of cellular signaling transductions and biological processes.
Ning Huang +6 more
doaj +1 more source
Genomic analysis of the TRIM family reveals two groups of genes with distinct evolutionary properties [PDF]
, 2008 Background The TRIM family is composed of multi-domain proteins that display the Tripartite Motif (RING, B-box and Coiled-coil) that can be associated with a C-terminal domain.
BALLABIO A +4 more
core +2 more sources
Journal of the Royal Statistical Society Series B: Statistical Methodology, 1980 Summary The jackknifed version of a regular estimate is the average of the sample pseudo-values, which in general are not independent and often have long-tailed distributions. We examine the simple alternative of the trimmed average of the pseudo-values, which is a naive type of robust estimate. The asymptotic theory is developed and two
Hinkley, David, Wang, Hai-Li
openaire +2 more sources