Results 71 to 80 of about 381,907 (293)
Development of a Supplemental Learning Material in Mathematics for Seamanship (Trim and Stability) [PDF]
This developmental research aimed to produce a supplemental learning material in Mathematics for Seamanship (Trim and Stability) using the ADDIE model. Mathematics concepts were determined through content analysis by examining the Seamanship Instructor’s
Clarence Kay Soliva Gabasa +1 more
doaj +1 more source
Least trimmed squares (LTS) is a statistical technique for estimation of unknown parameters of a linear regression model and provides a “robust” alternative to the classical regression method based on minimizing the sum of squared residuals.
Čížek, Pavel, Víšek, Jan Ámos
openaire +3 more sources
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Studying and Calculating the Radiation Damage Caused by the Solar Radiation Spectrum in the Crystal Structure of Semiconductor Components [PDF]
Space radiation environment has concerned about proper performance of electronic systems and equipment used in the space due to a variety of space radiations. The radiation hardening techniques are required to all parts of the system in such environment.
A. Esmaeilian +3 more
doaj
Configurational and system requirements for control of large space systems [PDF]
Control of large space systems, modeling, and control difficulties are discussed. Ground based analysis of spaceflight data are presented to determine structural dynamics characteristics for the purpose of revising control laws, and to trim the surface ...
Taylor, L. W., Jr.
core +1 more source
Occurrence and dissipation of the antibiotics sulfamethoxazole, sulfadiazine, trimethoprim, and enrofloxacin in the Mekong Delta, Vietnam [PDF]
The Mekong Delta in Vietnam has seen a rapid development and intensification of aquaculture in the last decades, with a corresponding widespread use of antibiotics.
Amelung, Wulf +6 more
core +3 more sources
A novel diversified multigene family of tripartite-motif (TRIM) intracellular receptors with putative antiviral activity has been identified in teleost fish and published in BMC Biology. The history of these receptors involves ancient linkage to paralogs of the major histocompatibility complex, and the family has invertebrate precursors.
openaire +2 more sources
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source

