Results 81 to 90 of about 454,552 (336)
Journal of the Royal Statistical Society Series B: Statistical Methodology, 1980 Summary The jackknifed version of a regular estimate is the average of the sample pseudo-values, which in general are not independent and often have long-tailed distributions. We examine the simple alternative of the trimmed average of the pseudo-values, which is a naive type of robust estimate. The asymptotic theory is developed and two
Hinkley, David, Wang, Hai-Li
openaire +2 more sources
Molecular Oncology, EarlyView.A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source
Studying and Calculating the Radiation Damage Caused by the Solar Radiation Spectrum in the Crystal Structure of Semiconductor Components [PDF]
فصلنامه علوم و فناوری فضایی, 2013 Space radiation environment has concerned about proper performance of electronic systems and equipment used in the space due to a variety of space radiations. The radiation hardening techniques are required to all parts of the system in such environment.
A. Esmaeilian +3 more
doaj
To TRIM or not to TRIM: the balance of host-virus interactions mediated by the ubiquitin system.
Journal of General Virology, 2019 The innate immune system responds rapidly to protect against viral infections, but an overactive response can cause harmful damage. To avoid this, the response is tightly regulated by post-translational modifications (PTMs).
Adam Hage, Ricardo Rajsbaum
semanticscholar +1 more source
Molecular Oncology, EarlyView.In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern +7 more
wiley +1 more source
The Uses of Adversity: Matthew Flinders' Mauritius Writings [PDF]
, 2002 A discussion of Matthew Flinders' 'Biographical Tribute to the Memory of Trim' and of an extended journal entry, both written while he was detained on ...
Dooley, Gillian Mary
core
Computer-Aided Design, 1999 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Blackmore, Denis +2 more
openaire +2 more sources
Emerging RNA-binding roles in the TRIM family of ubiquitin ligases
Biological chemistry, 2019 TRIM proteins constitute a large, diverse and ancient protein family which play a key role in processes including cellular differentiation, autophagy, apoptosis, DNA repair, and tumour suppression.
F. Williams +3 more
semanticscholar +1 more source
Identification of key genes and pathways for melanoma in the TRIM family
Cancer Medicine, 2020 Certain members of the TRIM family have been shown to have abnormal expression and prognostic value in cancer. However, in the development and progression of melanoma, the role of different TRIM family members remains unknown. To address this issue, this
Yijun Xia, Jun Zhao, Chunjun Yang
semanticscholar +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source