Results 221 to 230 of about 209,912 (265)
Characterisation of post-translational and transcriptional reprogramming of the immune response to ISAV and IPNV infections in salmon head kidney cells. [PDF]
Stewart R +8 more
europepmc +1 more source
TRIM52 Protects Against Doxorubicin-Induced Cardiac Inflammation, Oxidative Stress and Cardiac Injury. [PDF]
Zhang Z +8 more
europepmc +1 more source
The Roles of E3 Ubiquitin Ligases in Cerebral Ischemia-Reperfusion Injury. [PDF]
Li M, Yu X, Liu Q, Fang Z, Wang H.
europepmc +1 more source
Ubiquitin E3 Ligases and p53 in Doxorubicin-Induced Cardiotoxicity. [PDF]
Tachibana S +4 more
europepmc +1 more source
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M1-aminopeptidase family — beyond antigen-trimming activities
Current Opinion in Immunology, 2023Antigen (Ag)-trimming aminopeptidases belong to the oxytocinase subfamily of M1 metallopeptidases. In humans, this subfamily contains the endoplasmic reticulum aminopeptidases 1 and 2 (ERAP1 and 2) and the insulin-responsive aminopeptidase (IRAP, synonym oxytocinase), an endosomal enzyme. The ability of these enzymes to trim antigenic precursors and to
Irini Evnouchidou +3 more
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Emerging Role of TRIM Family Proteins in Cardiovascular Disease
Cardiology, 2020Ubiquitination is one of the basic mechanisms of cell protein homeostasis and degradation and is accomplished by 3 enzymes, E1, E2, and E3. Tripartite motif-containing proteins (TRIMs) constitute the largest subfamily of RING E3 ligases, with >70 current members in humans and mice.
Jing-Rui, Zhang +3 more
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TRIM family proteins: retroviral restriction and antiviral defence
Nature Reviews Microbiology, 2005Members of the tripartite motif (TRIM) protein family are involved in various cellular processes, including cell proliferation, differentiation, development, oncogenesis and apoptosis. Some TRIM proteins display antiviral properties, targeting retroviruses in particular. The potential activity of TRIM19, better known as promyelocytic leukaemia protein,
Sébastien, Nisole +2 more
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The interplay between viruses and TRIM family proteins
Reviews in Medical Virology, 2019SummaryNovel therapeutic options are urgently needed to improve the global treatment of viral infections. Tripartite motif (TRIM) family proteins are involved in various biological and cellular functions including differentiation, development, proliferation, oncogenesis, innate immunity, and viral autophagy.
Ramisha Khan +3 more
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Role of the tripartite motif (TRIM) family in female genital neoplasms
Pathology - Research and Practice, 2023The tripartite motif proteins (TRIMs) family represents a class of highly conservative proteins which play a large regulatory role in molecular processes. Recently, increasing evidence has demonstrated a role of TRIMs in female genital neoplasms. Our review thereby aimed to provide an overview of the biological involvement of TRIMs in female genital ...
Tianyu Liu +7 more
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