Results 61 to 70 of about 209,912 (265)
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Five golden rules for superstring phenomenology
, 2004 Recent measurements of the values of gauge coupling constants as well as neutrino properties support the idea of a grand unified (GUT) description of particle physics at a large scale of $M_{GUT}\sim 10^{16}$ GeV.
Nilles, Hans Peter
core +1 more source
Molecular Oncology, EarlyView.A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source
Molecular Oncology, EarlyView.In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern +7 more
wiley +1 more source
Neutrino Bi-Large Mixings and Family
, 2003 After a brief review of quark-lepton relations in grand unified theories (GUT), we show that the Pati-Salam relation with only one type of Higgs field configuration with "four zero symmetric texture" can reproduce two large neutrino mixings as well as ...
Bando, Masako, Obara, Midori
core +1 more source
Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine
Molecular Oncology, EarlyView.The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu +18 more
wiley +1 more source
PLoS ONE, 2011 BackgroundRhesus monkey TRIM5α (TRIM5αrh) recognizes the incoming HIV-1 core through its C-terminal B30.2(PRYSPRY) domain and promotes its premature disassembly or degradation before reverse transcription.
Seiga Ohmine +5 more
doaj +1 more source
Equidistribution estimates for eigenfunctions and eigenvalue bounds for random operators
, 2014 We discuss properties of $L^2$-eigenfunctions of Schr\"odinger operators and elliptic partial differential operators. The focus is set on unique continuation principles and equidistribution properties.
Borisov, Denis +2 more
core +1 more source
Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source
Einstein-aether gravity: theory and observational constraints
, 2007 Einstein-aether theory is general relativity coupled to a dynamical unit timelike vector field. A brief review of current theoretical understanding and observational constraints on the four coupling parameters of the theory is given.Comment: 8 pages, for
Jacobson, Ted
core +1 more source