Results 91 to 100 of about 12,013 (243)

Annual Banned‐Substance Review 17th Edition—Analytical Approaches in Human Sports Drug Testing 2023/2024

open access: yesDrug Testing and Analysis, Volume 17, Issue 8, Page 1417-1442, August 2025.
Scenarios of drug exposure and administration as well as detection assays for drugs and methods of sports doping published between 2023 and 2024 are critically reviewed and evaluated in context with the Prohibited List 2024 as established by the World Anti‐Doping Agency.
Mario  Thevis   +2 more
wiley   +1 more source

Ginkgo Biloba in the treatment of tinnitus: An updated literature review [PDF]

open access: yes, 2017
Introduction: Tinnitus is one of the common diseases of the ear that is associated with numerous physical and mental disorders. One of the known mechanisms in the tinnitus area with unknown reason is oxidative events. Based on the prevalence and economic
Asadi-Samani, Majid.   +3 more
core   +1 more source

The Liver Knows: Preoperative MELD Score as a Predictor of Outcome in Patients Undergoing Left Ventricular Assist Device Implantation. A Single‐Center Retrospective Cohort Study

open access: yesHealth Science Reports, Volume 8, Issue 7, July 2025.
ABSTRACT Background and Aims Right‐side heart failure (RSHF) jeopardizes left ventricular assist device (LVAD) short‐ and long‐term outcomes. The model for end‐stage liver disease (MELD) score is an effective means of evaluating liver dysfunction. This study aims to investigate the predictive utility of preoperative MELD on post‐LVAD implantation ...
Mohamed Elbayomi   +4 more
wiley   +1 more source

A network meta-analysis comparing perioperative outcomes of interventions aiming to decrease ischemia reperfusion injury during elective liver resection [PDF]

open access: yes, 2016
OBJECTIVE: This study sought to compare the perioperative outcomes of interventions aiming to decrease ischemia-reperfusion (IR) injury during elective liver resection.
Afxentiou, T   +4 more
core   +1 more source

MTFR2‐Mediated Fission Drives Fatty Acid and Mitochondrial Co‐Transfer from Hepatic Stellate Cells to Tumor Cells Fueling Oncogenesis

open access: yesAdvanced Science, Volume 12, Issue 23, June 20, 2025.
In the tumor margin of hepatocellular carcinoma (HCC), activated hepatic stellate cells upregulate MTFR2, initiating inhibiting DRP1 degradation and mitochondrial fission. This enhances mitochondrial availability and facilitates FAs synthesis via ACC1. Additionally, fission promotes RAC1‐mediated cytoskeletal remodeling and Miro1‐mediated mitochondrial
La Zhang   +9 more
wiley   +1 more source

Effectiveness of the original trimetazidine MR in patients with stable coronary heart disease and angina attacks resistant to trimetazidine generics (ETALON study)

open access: yesКардиоваскулярная терапия и профилактика, 2011
Aim. To assess the clinical benefits of the original trimetazidine medication (Preductal® MR) in patients with stable coronary heart disease and angina attacks resistant to trimetazidine generics. Material and methods.
A. V. Fendrikova, V. V. Skibitskyi
doaj   +1 more source

Central Beneficial Effects of Trimetazidine on Psychomotor Performance in Normal Healthy Volunteers

open access: yesAdvanced Biomedical Research, 2017
Background: Trimetazidine is a fatty oxidation inhibitor, leading to shifting of energy substrate from fatty acid oxidation toward glucose oxidation that leads to the reduction of oxygen requirement.
Hayder M Al-Kuraishy, Ali I Al-Gareeb
doaj   +1 more source

Modulating the metabolism by trimetazidine enhances myoblast differentiation and promotes myogenesis in cachectic tumor-bearing c26 mice. [PDF]

open access: yes, 2017
Trimetazidine (TMZ) is a metabolic reprogramming agent able to partially inhibit mitochondrial free fatty acid β-oxidation while enhancing glucose oxidation.
Chiandotto, S   +8 more
core   +3 more sources

Therapeutic drug monitoring and pharmacogenomic guided perhexiline therapy in kidney failure requiring haemodialysis: a case study

open access: yesJournal of Pharmacy Practice and Research, Volume 55, Issue 3, Page 244-247, June 2025.
Abstract Background Ischaemic heart disease is a leading cause of morbidity and mortality in haemodialysis patients, yet conventional therapies are often precluded due to increased perioperative risk and medication contraindications. Perhexiline, an antianginal agent, is contraindicated in renal impairment.
Harry Ashton, Hemant Kulkarni
wiley   +1 more source

Trimetazidine Is Associated With Ameliorated Stroke Risk in Patients With Both Ischemic Heart Disease and Atrial Fibrillation

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Myocardial ischemia is closely associated with arrhythmogenesis and prognostication in patients with atrial fibrillation (AF). Trimetazidine ameliorates myocardial ischemia through prioritizing cardiomyocyte metabolism to glucose oxidation ...
Yuen‐Ting Cheng   +5 more
doaj   +1 more source

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