Results 91 to 100 of about 12,230 (281)

TRIMETAZIDINE ADDITION TO ANTIANGINAL THERAPY: EFFECTS ON EFFICACY AND QUALITY OF LIFE IN PATIENTS WITH STABLE ANGINA TREATED OUTPATIENTLY

open access: yesТерапевтический архив, 2012
Aim. To compare effects of original trimetazidine versus its generics addition to antianginal treatment efficacy and quality of life in patients with stable angina (SA). Material and methods.
M A Shalenkova
doaj  

Cardioprotective Effect of Trimetazidine in Cardiac Contusion: Experimental Study

open access: yesОбщая реаниматология, 2008
Objective: to study the efficiency of pre-administration of trimetazidine in experimental cardiac contusion in order to lower the degree of posttraumatic myocardial dysfunction.
O. V. Korpacheva, V. T. Dolgikh
doaj   +1 more source

Hepatic Ischemia and Reperfusion Injury and Trauma: Current Concepts [PDF]

open access: yes, 2013
Context: Ischemia-reperfusion injury is a fascinating topic which has drawn a lot of interest in the last several years. Hepatic ischemia reperfusion injury may occur in a variety of clinical situations.
Papadopoulos, D.   +3 more
core   +2 more sources

Mitochondrial targets in ischaemic heart disease and heart failure, and their potential for a more efficient clinical translation. A scientific statement of the ESC Working Group on Cellular Biology of the Heart and the ESC Working Group on Myocardial Function

open access: yesEuropean Journal of Heart Failure, Volume 27, Issue 9, Page 1720-1736, September 2025.
Improving clinical translation of mitoprotective therapies. 31P MRI, phosphorus‐31 magnetic resonance imaging; hiPSC‐CM, human‐induced pluripotent stem cell‐derived cardiomyocyte; IHD, ischaemic heart disease. Abstract Acute myocardial infarction (MI) remains a major cause of death and disability worldwide.
Melanie Paillard   +29 more
wiley   +1 more source

Effect of trimetazidine on the functional capacity of ischemic heart disease patients not suitable for revascularization: Meta-analysis of randomized controlled trials

open access: yesPLoS ONE, 2022
Objective To explore the effect of adding trimetazidine to other anti-anginal drugs on the functional capacity of ischemic heart disease (IHD) patients not suitable for revascularization when compared to first-line antianginal drugs alone.
Alyaa M Ajabnoor, Amna H. Mukhtar
semanticscholar   +1 more source

Ginkgo Biloba in the treatment of tinnitus: An updated literature review [PDF]

open access: yes, 2017
Introduction: Tinnitus is one of the common diseases of the ear that is associated with numerous physical and mental disorders. One of the known mechanisms in the tinnitus area with unknown reason is oxidative events. Based on the prevalence and economic
Asadi-Samani, Majid.   +3 more
core   +1 more source

The crosstalk between immune activation and metabolism in heart failure. A scientific statement of the Heart Failure Association of the ESC

open access: yesEuropean Journal of Heart Failure, Volume 27, Issue 9, Page 1700-1719, September 2025.
Abstract A better understanding of additional mechanisms of heart failure (HF) progression may allow a different and more complete phenotyping of the disease and identification of novel therapeutic targets. Persistent latent myocardial inflammation/immune activation in HF may represent an attempt to restore tissue homeostasis in the failing heart ...
Gabriele Fragasso   +20 more
wiley   +1 more source

Trimetazidine has Promising Preventive Effects on Experimental Chronic Pancreatitis Rat Model.

open access: yesThe Turkish Journal of Gastroenterology, 2022
BACKGROUND It was aimed to evaluate the preventive efficacy of trimetazidine in an experimental chronic pancreatitis rat model. METHODS Chronic pancreatitis model was accomplished with caerulein and alcohol administration.
M. Kaplan   +6 more
semanticscholar   +1 more source

Epithelial–Mesenchymal Transition in Cancer: Insights Into Therapeutic Targets and Clinical Implications

open access: yesMedComm, Volume 6, Issue 9, September 2025.
This graphical abstract summarizes the effects of ionizing radiation (IR) on epithelial–mesenchymal transition (EMT), emphasizing critical processes such as DNA damage repair, tumor microenvironment interactions, and resistance mechanisms. It highlights EMT‐induced radioresistance regulators, such as TGF‐β, Wnt, Notch, ERK, and various miRNAs, as well ...
Dhasarathdev Srinivasan   +7 more
wiley   +1 more source

Beneficial effects of trimetazidine on expression of serotonin and serotonin transporter in rats with myocardial infarction and depression

open access: yesNeuropsychiatric Disease and Treatment, 2018
Meiyan Liu,1,* Wanlin Wei,2,* Christopher R Stone,3 Lijun Zhang,1 Guoxiang Tian,4 Jessie N Ding3 1Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, People’s Republic of China; 2Department of Cardiology, PLA ...
Liu MY   +5 more
doaj  

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