Results 71 to 80 of about 8,387 (243)

Trimetazidine in Practice [PDF]

open access: yesAmerican Journal of Therapeutics, 2016
All of the following traditional agents for the management of stable angina pectoris include the symptomatic treatment with heart rate-lowering agents such as β-blockers or non-dihydropyridine Ca-channel blockers, or ivabradine-the first selective sinus node If channel inhibitor-vasodilatators and preventive use of angiotensin-converting enzyme ...
openaire   +2 more sources

Blood Lactate as a Prognostic Biomarker for Survival and Weight Loss in Amyotrophic Lateral Sclerosis: An Exploratory–Validation Study

open access: yesAnnals of Neurology, Volume 99, Issue 6, Page 1526-1535, June 2026.
Objective Lactate is increasingly recognized as an energy substrate, but its relevance to amyotrophic lateral sclerosis (ALS) remains unclear. We examined whether blood lactate is associated with survival and weight loss in ALS. Methods This retrospective study included an Australian exploratory cohort and a Japanese validation cohort with clinical ...
Ryutaro Nakamura   +8 more
wiley   +1 more source

TRIMETAZIDINE ADDITION TO ANTIANGINAL THERAPY: EFFECTS ON EFFICACY AND QUALITY OF LIFE IN PATIENTS WITH STABLE ANGINA TREATED OUTPATIENTLY

open access: yesТерапевтический архив, 2012
Aim. To compare effects of original trimetazidine versus its generics addition to antianginal treatment efficacy and quality of life in patients with stable angina (SA). Material and methods.
M A Shalenkova
doaj  

Evaluation of the Efficacy and Safety of Chinese Herbal Injection Combined With Trimetazidine for Viral Myocarditis: A Network Meta-Analysis

open access: yesFrontiers in Pharmacology, 2021
Background: Viral myocarditis (VMC) is a common emergency of cardiovascular disease. Current treatment for VMC includes the prohibition of exercise plus supportive and symptomatic treatment, given the lack of specific antiviral therapeutic options and ...
Kerui Wu   +7 more
doaj   +1 more source

Trimetazidine enhances myocardial angiogenesis in pressure overload-induced cardiac hypertrophy mice through directly activating Akt and promoting the binding of HSF1 to VEGF-A promoter

open access: yesActa Pharmacologica Sinica, 2022
Latest clinical research shows that trimetazidine therapy during the perioperative period relieves endothelial dysfunction in patients with unstable angina induced by percutaneous coronary intervention. In this study we investigated the effects of TMZ on
Hong-Yang Shu   +6 more
semanticscholar   +1 more source

Dried blood spot analysis in antidoping: Technical challenges, analytical advances, and future perspectives

open access: yesBulletin of the Korean Chemical Society, Volume 47, Issue 6, Page 674-688, June 2026.
Dried blood spot (DBS) analysis enables minimally invasive blood collection with strong analyte stability and simplified logistics, supporting anti‐doping applications beyond traditional matrices. Recent advances address hematocrit, volume variability, and matrix effects while expanding coverage to steroid esters, World Anti‐Doping Agency‐listed ...
Jihyun Yoon   +4 more
wiley   +1 more source

Trimetazidine mitigates high glucose-induced retinal endothelial dysfunction by inhibiting PI3K/Akt/mTOR pathway-mediated autophagy

open access: yesBioengineered, 2022
Trimetazidine (TMZ), as a metabolic regulator, has been widely testified to exhibit positive therapeutic effects on various disease models, but its role in diabetic retinopathy has not been reported. Therefore, this study was designed with the purpose of
Qing-Song Yang   +6 more
semanticscholar   +1 more source

The Possible Osteoarthritis Disease Modifying Effect Of Trimetazidine In Rats [PDF]

open access: yes
Background: Osteoarthritis (OA) which is the most prevalent chronic joint disease and a primary contributor to pain and physical disability, impacting millions of individuals globally.
Ali Gaballah, Amal Hassanin, Doaa Hellal, Ramy A. Abdelsalam and Amany Atia
core   +1 more source

The Impact of Trimetazidine on Cardiac Fibrosis, Inflammation, and Function in Ischemic Cardiomyopathy Patients

open access: yesCardiovascular Drugs and Therapy, 2022
Background Previous studies have shown that Trimetazidine (TMZ) improves vascular endothelial function and reduces the inflammatory process progression.
N. M. El-khodary   +3 more
semanticscholar   +1 more source

Dopamine‐Induced Seizure in a Heart Failure Patient: A Case Report and Review of Neurotoxic Implications

open access: yesClinical Case Reports, Volume 14, Issue 5, May 2026.
ABSTRACT In heart failure patients, dopamine therapy, particularly at higher doses, may induce seizures due to its impact on cerebral blood flow and exacerbation of underlying hypoxemia and electrolyte imbalances. Close monitoring and cautious use of dopamine, with consideration of alternative inotropic agents like dobutamine, are essential to mitigate
Chuanwei Zhao   +4 more
wiley   +1 more source

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