Results 101 to 110 of about 12,013 (243)
Ranolazine: a new possibility and a new mechanism in the treatment of chronic angina pectoris. [PDF]
, 2011 In treatment of chronic angina pectoris in the last few years, besides the medicines with antianginal effect (adrenergic receptor beta blockers, calcium antagonists and nitrates) even ranolazine may be applied.
Goran Krstačić
core +1 more source
Transient mitochondrial permeability transition pore opening mediates preconditioning-induced protection [PDF]
, 2004 Background - Transient (low-conductance) opening of the mitochondrial permeability transition pore (mPTP) may limit mitochondrial calcium load and mediate mitochondrial reactive oxygen species (ROS) signaling.
Duchen, M +3 more
core +1 more source
European Journal of Heart Failure, Volume 27, Issue 5, Page 747-759, May 2025.Linking guideline‐directed medical therapy (GDMT) implementation and appropriate polypharmacy management in heart failure (HF). Polypharmacy can represent a barrier to the proper implementation of life‐prolonging GDMT for HF. A reasonable balance between the optimization of GDMT and avoiding inappropriate polypharmacy is mandatory in the contemporary ...
Davide Stolfo +27 more
wiley +1 more source
MODERN PECULIARITIES OF MYOCARDIAL CYTOPROTECTION IN THERAPY OF ISHEMIC HEART DISEASE PATIENTS
Медицинский совет, 2016 Results of meta-analysis of more than 20 clinical studies of use of various dosages and schemes of indication of trimetazidine to stable ischemic heart disease patients allowed considering the daily dosage of trimetazidine 70 mg as a standard therapeutic
Z. M. SIZOVA, S .K. VLADIMIROV
doaj +1 more source
Old and new intravenous inotropic agents in the treatment of advanced heart failure [PDF]
, 2011 Inotropic agents are administered to improve cardiac output and peripheral perfusion in patients with systolic dysfunction and low cardiac output. However, there is evidence of increased mortality and adverse effects associated with current inotropic ...
Bettari L +3 more
core +1 more source
Kidney Fibrosis In Vitro and In Vivo Models: Path Toward Physiologically Relevant Humanized Models
Advanced Healthcare Materials, Volume 14, Issue 9, April 4, 2025.This review discusses kidney diseases with a focus on kidney fibrosis and the models currently used. It highlights the limitations of animal and 2D in vitro models in replicating human kidney anatomy and physiology. Consequently, there is a significant need for humanized 3D in vitro models, such as 3D cell aggregates, membranes and hydrogels, on‐chip ...
Gabriele Addario +2 more
wiley +1 more source
Российский кардиологический журнал, 2004 In 57 patients with stable effort angina, functional class II-III, and episodes of silent myocardial ischemia, antianginal and antiischemic efficacy of trimetazidine, isosorbide-5-mononitrate, and nadolol (monotherapy and combined therapy) was compared ...
S. N. Vaslyaeva +3 more
doaj
MEMBRANE-SАVING ACTION OF TRIMETAZIDINE IN SUBJECTS WITH ACUTE MYOCARDIAL INFARCTION
Российский кардиологический журнал, 2014 The article concerns the assessment of functional condition of cell membranes in a variety of pathological conditions, influence of various physical and chemical factors and pharmacological drugs. Aim.
S. V. Vasilyev +2 more
doaj +1 more source
Pharmacoepidemiology and Drug Safety, Volume 34, Issue 3, March 2025.ABSTRACT Background Direct Healthcare Professional Communications (DHPCs) are an important risk minimisation measure. Their effect has been shown to be variable and has been measured using different outcomes and study populations. Depending on the content of the message, the optimal outcome to measure a direct effect of the DHPC can differ.
Esther de Vries +3 more
wiley +1 more source
Myocardial substrate metabolism in the normal and failing heart [PDF]
, 2005 The alterations in myocardial energy substrate metabolism that occur in heart failure, and the causes and consequences of these abnormalities, are poorly understood.
LOPASCHUK G.D. +2 more
core +1 more source