Results 81 to 90 of about 12,230 (281)

Cardiac Calcitropes, Myotropes, and Mitotropes: JACC Review Topic of the Week. [PDF]

, 2019
The term "inotrope" is familiar and intimately connected with pharmaceuticals clinically used for treatment of low cardiac output with cardiogenic shock.
Adams, KF, Allen, LA, Francis, GS, Gottlieb, SS, Lancellotti, P, Psotka, MA, Rosano, GMC, Teerlink, JR   +7 more
core   +2 more sources

Further Insights Into Anticholinergic Action Informed by Japanese Anticholinergic Risk Scale

Geriatrics &Gerontology International, Volume 26, Issue 1, January 2026.
ABSTRACT The increased anticholinergic burden caused by medications in older adults is one of the adverse drug reactions of particular concern, as it can exacerbate the onset of geriatric syndromes or induce cognitive dysfunction, and is also related to the issue of polypharmacy.
Masaki Mogi, Shuang Liu, Yasuyuki Suzuki, Yuuka Shibata, Shizuo Yamada   +4 more
wiley   +1 more source

Trimetazidine improves left ventricular function in diabetic patients with coronary artery disease: a double-blind placebo-controlled study

Cardiovascular Diabetology, 2003
Background Patients with diabetic cardiomyopathy have an impaired myocardial glucose handling and distal distribution of coronary atherosclerosis. Trimetazidine, an anti-ischemic metabolic agent, improves myocardial glucose utilization though inhibition ...
Mercuro Giuseppe, Sposato Barbara, Vitale Cristiana, Rosano Giuseppe MC, Fini Massimo   +4 more
doaj   +1 more source

Pharmacological strategies in lung cancer-induced cachexia: effects on muscle proteolysis, autophagy, structure, and weakness [PDF]

, 2014
Muscle wasting and cachexia are important systemic manifestations of highly prevalent conditions including cancer. Inflammation, oxidative stress, autophagy, ubiquitin-proteasome system, nuclear factor (NF)-kB, and mitogen activated protein kinases (MAPK)
Bal, Elisa Dora, Barreiro, Eshter, Chacon Cabrera, Alba, Diament, Miriam, Fermoselle, Clara, Mateu Jimenez, Mercè, Sandri, Marco, Urtreger, Alejandro Jorge   +7 more
core   +1 more source

Effectiveness of Proanthocyanidin plus Trimetazidine in the Treatment of Non-Small-Cell Lung Cancer with Radiation Heart Injury

Evidence-Based Complementary and Alternative Medicine, 2022
This study was intended to explore the effect of proanthocyanidin (PC) combined with trimetazidine in non-small-cell lung cancer (NSCLC) with radiation-induced heart damage (RIHD).
H. Yin, Yue Zhao, Yucui Sun, Jia Liu, Yingjun Han, Zhentao Dai   +5 more
semanticscholar   +1 more source

State‐of‐the‐Art, Insights, and Perspectives for MOFs‐Nanocomposites and MOF‐Derived (Nano)Materials

Advanced Materials, Volume 37, Issue 52, December 29, 2025.
Different approaches to MOF‐NP composite formation, such as ship‐in‐a‐bottle, bottle‐around‐the‐ship and in situ one‐step synthesis, are used. Owing to synergistic effects, the advantageous features of the components of the composites are beneficially combined, and their individual drawbacks are mitigated.
Stefanos Mourdikoudis, Subhajit Dutta, Saqib Kamal, Sergio Gómez‐Graña, Isabel Pastoriza‐Santos, Stefan Wuttke, Lakshminarayana Polavarapu   +6 more
wiley   +1 more source

Predictors of restenosis following percutaneous coronary stent implantation: The role of trimetazidine therapy

Frontiers in Cardiovascular Medicine, 2022
Aims In-stent restenosis (ISR) is an unresolved problem following percutaneous coronary intervention (PCI), having a negative impact on clinical outcome.
Gábor Csató, N. Erdei, B. Ványai, Tímea Balla, D. Czuriga, Z. Csanádi, Z. Kőszegi, I. Edes, G. Szabó   +8 more
semanticscholar   +1 more source

Особенности кардиопротекторного эффекта триметазидина при экспериментальном кардиосклерозе у крыс с различной степенью чувствительности к гипоксии [PDF]

, 2015
ГИПОКСИЯАНОКСИЯЛИПИДОВ ПЕРЕКИСНОЕ ОКИСЛЕНИЕПЕРЕКИСНОЕ ОКИСЛЕНИЕ ЛИПИДОВСКЛЕРОЗкардиосклероз ...
Сатурская, А. С.
core  

Physiological monitoring in the complex multi-morbid heart failure patient - Introduction. [PDF]

, 2019
Repeated physiological monitoring of comorbidities in heart failure (HF) is pivotal. This document introduces the main challenges related to physiological monitoring in the complex multimorbid HF patient, arising during an ESC consensus meeting on this ...
Rosano, GMC, Seferović, PM
core   +1 more source

The emerging role of Nrf2 in heart failure: From cardioprotection to therapeutic approaches

ESC Heart Failure, Volume 12, Issue 6, Page 4000-4020, December 2025.
Nrf2 signalling is impaired in heart failure, contributing to oxidative stress, mitochondrial dysfunction, and ferroptosis, which drive neurohormonal activation, inflammation, and ischaemia‐reperfusion injury. This loss of Nrf2 activity exacerbates hypertension, diabetic cardiomyopathy, and cardiotoxicity, accelerating progression to overt heart ...
Emiliano Fiori, Sergio Davinelli, Armando Ferrera, Alessandro Medoro, Carlo Barsali, Allegra Battistoni, Maurizio Volterrani, Massimo Volpe, Luciano Saso, Speranza Rubattu   +9 more
wiley   +1 more source