Results 1 to 10 of about 31,760 (183)

Burkholderia pseudomallei in Sarawak, Malaysian Borneo, Remains Highly Susceptible to Trimethoprim-Sulfamethoxazole Despite Resistance to Its Individual Components [PDF]

Pathogens
Burkholderia pseudomallei, the causative agent of melioidosis, is endemic in Sarawak, Malaysian Borneo, where it is represented by a unique gentamicin-susceptible population. Despite trimethoprim-sulfamethoxazole (co-trimoxazole) being the cornerstone of
Liana Lantong Sumbu, Tonnii Loong-Loong Sia, Mong-How Ooi, Anand Mohan, Jin-Shyan Wong, Yuwana Podin   +5 more
doaj   +2 more sources

Case Report: Pulmonary nocardiosis: three case reports and literature review [PDF]

Frontiers in Medicine
Pulmonary nocardiosis is a relatively uncommon opportunistic infection characterized by nonspecific clinical features, often leading to delays in diagnosis and treatment.
Qi Zhao, Min Wang, Xincheng Nie, LIna Fu, Xuehao Fu   +4 more
doaj   +2 more sources

Pharmacometabolomics Study of Sulfamethoxazole and Trimethoprim in Kidney Transplant Recipients: Real-World Metabolism and Urinary Excretion [PDF]

Metabolites
Background/Objectives: The increased use of antibiotics is raising concerns about environmental contamination and antibiotic resistance, exemplified by the case of cotrimoxazole, a widely prescribed combination of sulfamethoxazole and trimethoprim. After
Marieke A. J. Hof, Hessel de Haan, Stepan Stepanovic, Stephan J. L. Bakker, Eelko Hak, Gérard Hopfgartner, Frank Klont, TransplantLines Investigators   +7 more
doaj   +2 more sources

Multisensory Systems Based on Perfluorosulfonic Acid Membranes Modified with Functionalized CNTs for Determination of Sulfamethoxazole and Trimethoprim in Pharmaceuticals

Membranes, 2022
Sulfamethoxazole and trimethoprim are synthetic bacteriostatic drugs. A potentiometric multisensory system for the analysis of sulfamethoxazole and trimethoprim combination drugs was developed.
Anna Parshina, Anastasia Yelnikova, Ekaterina Safronova, Tatyana Kolganova, Victoria Kuleshova, Olga Bobreshova, Andrey Yaroslavtsev   +6 more
doaj   +1 more source

Case Report: Disseminated Nocardiosis Caused by Nocardia vulneris in a Patient With Macroglobulinemia

Frontiers in Public Health, 2022
This report describes a case of disseminated nocardiosis, caused by Nocardia vulneris, in a 61-year-old man with macroglobulinemia and presenting with repeated fever, cough, shortness of breath, and muscle pain. The isolated Nocardia strain was resistant
Fulan Qiu, Zhiyi Ma, Rongrong Zhong, Haonan Huang, Yuehua Wang, Hui Liu   +5 more
doaj   +1 more source

Clinical manifestations and antimicrobial susceptibility of Nocardia species at a tertiary hospital in Taiwan, 2011–2020

Journal of the Formosan Medical Association, 2022
Background: The study aimed to assess the clinical characteristics of patients with nocardiosis, to evaluate the in vitro susceptibility of antimicrobial agents against Nocardia species, and to explore changes in antimicrobial susceptibilities in this ...
Chong Kei Lao, Mei-Chueh Tseng, Cheng-Hsun Chiu, Nan-Yu Chen, Chih-Hung Chen, Wen-Hung Chung, Tsui-Ping Liu, Jang-Jih Lu, Hsin-Chih Lai, Lan-Yan Yang, Chia-Hui Lee, Ting-Shu Wu   +11 more
doaj   +1 more source

Perfluorosulfonic Acid Membranes Modified with Polyaniline and Hydrothermally Treated for Potentiometric Sensor Arrays for the Analysis of Combination Drugs

Membranes, 2023
A novel potentiometric multisensory system for the analysis of sulfamethoxazole and trimethoprim combination drugs was developed. The potentiometric sensors (Donnan potential (DP) was used as an analytical signal) with an inner reference solution were ...
Anna Parshina, Anastasia Yelnikova, Tatyana Kolganova, Tatyana Titova, Polina Yurova, Irina Stenina, Olga Bobreshova, Andrey Yaroslavtsev   +7 more
doaj   +1 more source

Manifestations and Management of Trimethoprim/Sulfamethoxazole–Resistant Nocardia otitidiscaviarum Infection

Emerging Infectious Diseases, 2023
Nocardia can cause systemic infections with varying manifestations. Resistance patterns vary by species. We describe N. otitidiscavarium infection with pulmonary and cutaneous manifestations in a man in the United States. He received multidrug treatment
Katherine Fu, Kyle White, Aliaksandr Ramaniuk, Vidya Kollu, Daniel Urbine   +4 more
doaj   +1 more source

Dosage Optimisation of Trimethoprim and Sulfamethoxazole for the Treatment of an Avian Pathogenic Strain of Escherichia coli in Broiler Chickens

Antibiotics, 2023
Based on pharmacokinetic studies carried out according to the methodologies defined by the European Medicines Agency (EMA) using mass spectrometry analysis, a new formulation of a veterinary drug for the treatment of broiler chickens is proposed ...
Kamil Stastny, Nikola Hodkovicova, Martin Jerabek, Michal Petren, Michaela Viskova, Aneta Papouskova, Iva Bartejsova, Kristina Putecova-Tosnerova, Michaela Charvatova, Monika Zouharova, Katarina Matiaskova, Katerina Nedbalcova   +11 more
doaj   +1 more source

The Inhibitory Effect of Adenylic Acid on the Bitterness of the Antibacterial Combination Drug Trimethoprim/Sulfamethoxazole

Chemical and Pharmaceutical Bulletin, 2023
The purpose of the present study was to evaluate bitterness suppression effect of adenylic acid (AMP) as a nucleotide-derived nutrient enhancer on a bitter commercial drug. In the present study, we evaluated peripheral bitterness inhibition effect of AMP on the trimethoprim (TMP) and sulfamethoxazole (SMZ) combination formulation based on taste sensor.
Jun, Kawahara, Miyako, Yoshida, Honami, Kojima, Rio, Uno, Minoru, Ozeki, Ikuo, Kawasaki, Masaaki, Habara, Hidekazu, Ikezaki, Takahiro, Uchida   +8 more
openaire   +2 more sources