Results 71 to 80 of about 21,486 (179)

Case Report: Bloodstream infection with Nocardia cyriacigeorgica in a patient with diffuse large B-cell lymphoma

Frontiers in Medicine
Nocardia bacteremia is a rare but life-threatening opportunistic infection associated with high mortality rates. Early diagnosis and prompt initiation of appropriate treatment are crucial for improving patient outcomes.
Ning Du, Bingqing Xu, Hongmin Wang, Haochun Tang, Jianping Li, Jun Meng, Dan You   +6 more
doaj   +1 more source

A Quantitative Model to Estimate Drug Resistance in Pathogens

Journal of Fungi, 2016
Pneumocystis pneumonia (PCP) is an opportunistic infection that occurs in humans and other mammals with debilitated immune systems. These infections are caused by fungi in the genus Pneumocystis, which are not susceptible to standard antifungal agents ...
Frazier N. Baker, Melanie T. Cushion, Aleksey Porollo   +2 more
doaj   +1 more source

A Review of Virtual Twins in Physiologically‐Based Pharmacokinetic Modeling and Simulation

Clinical Pharmacology &Therapeutics, Volume 120, Issue 2, Page 324-333, August 2026.
The novel application of Virtual Twins (VT) in PBPK (VT‐PBPK) presents the opportunity to advance precision dosing and accelerate the shift from one‐size‐fits‐all to targeted, individualized treatments. This review aims to: (1) critically evaluate existing research on the use of VTs in PBPK, (2) develop a conceptual definition of VT‐PBPK, (3) describe ...
Emily Mannix, Sam Mostafa, Amin Rostami‐Hodjegan, Thomas M. Polasek, Carl M. J. Kirkpatrick   +4 more
wiley   +1 more source

Randomized controlled trial of standard versus double dose cotrimoxazole for childhood pneumonia in Pakistan

Bulletin of the World Health Organization, 2005
OBJECTIVE: Increasing concern over bacterial resistance to cotrimoxazole, which is recommended by WHO as a first-line drug for treating non-severe pneumonia, led to the suggestion that this might not be optimal therapy.
Rasmussen Zeba A., Bari Abdul, Qazi Shamim, Rehman Gul, Azam Iqbal, Khan SherBaz, Aziz Farida, Rafi Sadia, Roghani Mehr Taj, Iqbal Imran, Nagi Abdul Ghaffar, Hussain Waqar, Bano Nahida, van Latum late J.C., Khan Mushtaq   +14 more
doaj  

Assessment of carvacrol-antibiotic combinations’ antimicrobial activity against methicillin-resistant Staphylococcus aureus

Frontiers in Microbiology
IntroductionThis study aimed to assess the antimicrobial activity of carvacrol in combination with approved antibiotics against methicillin-resistant Staphylococcus aureus (MRSA).
Deniz Al-Tawalbeh, Yazan Alkhawaldeh, Hana M. Sawan, Farah Al-Mamoori, Ali Al-Samydai, Amal Mayyas   +5 more
doaj   +1 more source

On‐site pilot‐scale advanced oxidation pretreatment of hospital wastewater: assessment of pharmaceuticals, pathogens, antibiotic resistance genes and acute ecotoxicity

Journal of Chemical Technology &Biotechnology, Volume 101, Issue 8, Page 1478-1491, August 2026.
Abstract BACKGROUND Hospital premises generate wastewater containing a wide spectrum of contaminants, such as pharmaceutically active compounds (PhACs), antibiotic resistance genes (ARGs) and pathogenic microorganisms, whilst plenty of them are classified under the antibiotic resistant bacteria (ΑRΒ) category.
Andreas Kaliakatsos, Iosifina Gounaki, Spyros Dokianakis, Georgios Gkotsis, Maria‐Christina Nika, Eleni Aleiferi, Athanasios S Stasinakis, Nikos Katsarakis, Nikolaos S Thomaidis, Thrassyvoulos Manios, Michalis S Fountoulakis, Danae Venieri   +11 more
wiley   +1 more source

Primary CNS Anaplastic Large Cell Lymphoma DUPS22 Rearranged with Gain of ALK: A Case Report and Review of the Literature

eJHaem, Volume 7, Issue 4, August 2026.
ABSTRACT ALK‐negative anaplastic large cell lymphoma (ALCL) is a rare primary central nervous system lymphoma (PCNSL). Although DUSP22 rearrangement is considered favorable in systemic ALK‐negative ALCL, survival remains poor in PCNSL. We report a case of PCNSL ALK‐negative ALCL with DUSP22‐IRF4 rearrangement and an unusual gain of the ALK gene (2p23),
Sindu Iska, María Herrán, Zackary Anderson, Pablo Bejarano, Silvia Bunting, Chieh‐Lin Fu   +5 more
wiley   +1 more source

Mania secondary to cotrimoxazole antibiotherapy: a case report and review of literature

Journal of Medical Case Reports
Background Antibiomania is the manifestation of manic symptoms secondary to taking an antibiotic, which is a rare side effect. In these cases, the antibiotics most often incriminated are macrolides and quinolones, but to our knowledge, there are no ...
Marine Jouart, Tahiana Ramaholimihaso, Jed Hadjoudj, Messaline Bermejo, Arthur Kaladjian   +4 more
doaj   +1 more source

One Health Insights From Pteropus medius: Nipah Virus Spillover, Microbiota, and Antimicrobial Resistance

MicrobiologyOpen, Volume 15, Issue 4, August 2026.
Environmental and anthropogenic drivers of antibiotic resistance dissemination. The cycle reinforces how anthropogenic inputs, such as sewage, animal dung, hospital effluent, and agricultural runoff bring resistant bacteria and antibiotic residues into soil and water.
Punam Chowdhury, Shah Md Tanvir Khan, Sajal Roy, Md. Shohel Al Faruk   +3 more
wiley   +1 more source

A case of corneal opacity caused by atovaquone administration

American Journal of Ophthalmology Case Reports
Purpose: Atovaquone is an alternative drug that is used for the prevention and treatment of Pneumocystis pneumonia when the first-line drug, sulfamethoxazole-trimethoprim (ST combination), cannot be used due to side effects.
Takeyoshi Ashizuka, Masafumi Uematsu, Mohamed Talaat Mohamed, Mao Kusano, Mohamed Yasser Helmy, Daisuke Inoue, Takashi Kitaoka   +6 more
doaj   +1 more source