Results 111 to 120 of about 99,360 (296)

Trimethoprim, creatinine and creatinine-based equations [PDF]

, 2011
peer reviewedCo-trimoxazole is a frequently prescribed antibiotic worldwide. It is composed of both trimethoprim and sulfamethoxazol (Sfx) and is used in the treatment and prophylaxis of urinary tract and Pneumocystis jirovecii infections.
KRZESINSKI, Jean-Marie, Jean-Marie Krzesinski, Etienne Cavalier, DELANAYE, Pierre, Christophe Mariat, Nicolas Maillard, White, Christine, Maillard, Nicolas, Mariat, Christophe, Pierre Delanaye, Christine A. White, CAVALIER, Etienne   +11 more
core   +1 more source

Diagnosis and management of neutropenia in adults: Expert guidance

British Journal of Haematology, EarlyView.
Severe neutropenia can result from decreased production of neutrophil precursors in the bone marrow, as in the case of severe congenital neutropenia, or from increased utilization of neutrophils or their accelerated destruction as for drug‐induced neutropenia or autoimmune neutropenia. Severe chronic neutropenia increases susceptibility to bacterial or
Karl Welte, Cornelia Zeidler, Julia Skokowa, Sabine Mellor‐Heineke, Audrey Anna Bolyard, David Dale   +5 more
wiley   +1 more source

Crystal engineering of analogous and homologous organic compounds: hydrogen bonding patterns in trimethoprim hydrogen phthalate and trimethoprim hydrogen adipate

, 2006
BackgroundTrimethoprim [2,4-diamino-5-(3',4',5'-trimethoxybenzyl)pyrimidine] is an antifolate drug. It selectively inhibits the bacterial dihydrofolate reductase (DHFR) enzyme.ResultsIn the crystal structures of trimethoprim (TMP)-hydrogen phthalate (1 ...
Urszula Rychlewska, Packianathan Thomas Muthiah, Savarimuthu Francis, Beata Warżajtis   +3 more
core   +1 more source

Patch Testing in Paediatric Drug Hypersensitivity Reactions: Current Evidence and Clinical Implications

Contact Dermatitis, EarlyView.
ABSTRACT Drug hypersensitivity reactions (DHRs) are common in children and are diagnostically challenging, with cutaneous manifestations being the most common presentation. Patch testing (PT) is a well‐established tool for investigating delayed T‐cell‐mediated reactions and is widely used in patients with contact dermatitis.
Gabriele Simonetti, Francesco Catamerò, Giulia Liccioli, Leonardo Tomei, Simona Barni, Mattia Giovannini, Lucrezia Sarti, Francesca Mori   +7 more
wiley   +1 more source

Pseudomembranous Colitis Following Low Dose Trimethoprim-Sulfamethoxazole

, 1985
A 94-year-old man had pseudomembranous colitis while taking low dose trimethoprim-sulfamethoxazole for recurrent urinary tract infection. The suppressive effect of low dose trimethoprim-sulfamethoxazole on normal colonic flora appeared to be a factor in ...
London, R, John Jaffe, Jaffe, J, Joseph Candio, Candio, Joseph, MD, Dennis Ruff, Richard London, Ruff, D   +7 more
core   +1 more source

Risk Factors of Blood Culture Positivity and Mortality in Bloodstream Infections: A Population‐Based Study of Patients With B‐Cell Malignancies

European Journal of Haematology, EarlyView.
ABSTRACT Background Bloodstream infections remain a major cause of mortality among cancer patients. Pathogen surveillance and risk stratification tools are key to improved management. This study describes trends in causative pathogens and explores risk factors for positive blood cultures (PBCs) and post‐infection mortality in cancer patients.
Mathias Holmsgaard Eskesen, Alexander Djupnes Fuglkjær, Tarec Christoffer El‐Galaly, Paw Jensen, Izabela Ewa Nielsen, Laurids Østergaard Poulsen, Mikkel Runason Simonsen, Kirstine Kobberøe Søgaard   +7 more
wiley   +1 more source

Trimethoprim-sulfamethoxazole in cyst fluid from autosomal dominant polycystic kidneys

, 1987
Trimethoprim-sulfamethoxazole in cyst fluid from autosomal dominant polycystic kidneys. Cyst infection in patients with autosomal-dominant polycystic kidney disease (ADPKD) is often refractory to therapy, in part because of the limited entry of commonly ...
Golper, Thomas A., Elzinga, Lawrence W., Bennett, William M., Rashad, Abdel L., Carr, Mary E.   +4 more
core   +1 more source

Surgical removal of a perirectal melanoma through sphincterotomy and rectal wall resection in a horse

Equine Veterinary Education, EarlyView.
Summary Melanomas are among the most frequent neoplasms in grey horses. Deep perirectal melanomas, however, are uncommon and challenging to excise due to their proximity to the peritoneal reflection. This report describes the successful standing removal of a large (16 × 8 × 6 cm) perirectal melanoma firmly adherent to the dorsal rectal wall in a 19 ...
R. Becker, C. Koch, M. de Preux
wiley   +1 more source

Genetics of resistance to trimethoprim in cotrimoxazole resistant uropathogenic Escherichia coli: integrons, transposons, and single gene cassettes

Frontiers in Microbiology
Cotrimoxazole, the combined formulation of sulfamethoxazole and trimethoprim, is one of the treatments of choice for several infectious diseases, particularly urinary tract infections.
María Eloísa Poey, Eliana de los Santos, Diego Aznarez, César X. García-Laviña, Magela Laviña   +4 more
doaj   +1 more source

Mitral regurgitation and decompensated heart failure in a young pregnant pony mare: An aetiological challenge

Equine Veterinary Education, EarlyView.
Summary A 4‐year‐old, 6‐month pregnant, Welsh pony mare presented with severe acute clinical signs including depression, anorexia, pale mucous membranes, tachycardia with a grade 4/6 holosystolic murmur and moderate expiratory dyspnoea with diffuse wheezes. There was no evidence of placentitis or fetal distress.
M. F. David, L. Cannon, A. Tortereau, A. Thomas‐Cancian, I. Desjardins   +4 more
wiley   +1 more source