Results 11 to 20 of about 123,230 (304)

A trimethoprim derivative impedes antibiotic resistance evolution

Nature Communications, 2021
The antibiotic trimethoprim (TMP) is used to treat a variety of Escherichia coli infections, but its efficacy is limited by the rapid emergence of TMP-resistant bacteria.
M. Manna, Y. T. Tamer, I. Gaszek, Nicole Poulides, Ayesha M. Ahmed, Xiaoyu Wang, Furkan C R Toprak, Danae R Woodard, A. Koh, Noelle S. Williams, D. Borek, A. Atilgan, J. Hulleman, C. Atilgan, U. Tambar, Erdal Toprak   +15 more
semanticscholar   +1 more source

Effects of ciprofloxacin, trimethoprim, and amoxicillin on microbial structure and growth as emerging pollutants reaching crop soils.

Environmental Research, 2022
The presence of emerging pollutants, and specifically antibiotics, in agricultural soils has increased notably in recent decades, causing growing concern as regards potential environmental and health issues.
Laura Rodriguez‐Gonzalez, Avelino Núñez-Delgado, E. Álvarez-Rodríguez, E. García-Campos, Angela B. Martin, M. Díaz-Raviña, M. Arias-Estévez, D. Fernández-Calviño, V. Santás-Miguel   +8 more
semanticscholar   +1 more source

Trimethoprim-Sulfamethoxazole

Definitions, 2020
A This synergistic combination, also known as Co-Trimoxazole, inhibits two sequential steps in the bacterial metabolism of folic acid. Trimethoprim is a pyrimidine inhibitor of dihydrofolate reductase; sulfamethoxazole is a sulfamide inhibitor of ...

semanticscholar   +1 more source

Sulfamethoxazole/Trimethoprim ratio as a new marker in raw wastewaters: A critical review.

Science of the Total Environment, 2020
Global Trimethoprim (TMP) and Sulfamethoxazole (SMX) occurrences in raw wastewaters were systematically collected from the literature (n = 140 articles) in order to assess the relevance of using the SMX/TMP ratio as a marker of the main origin of ...
Thomas Thiebault
semanticscholar   +1 more source

HLA-B*14:01 and HLA-B*35:01 are associated with trimethoprim-sulfamethoxazole induced liver injury

Hepatology, 2020
Trimethoprim (TMP)–sulfamethoxazole (SMX) is an important cause of idiosyncratic drug‐induced liver injury (DILI), but its genetic risk factors are not well understood.
Yi-Ju Li, E. Phillips, A. Dellinger, P. Nicoletti, R. Schutte, Danmeng Li, D. Ostrov, R. Fontana, P. Watkins, A. Stolz, A. Daly, G. Aithal, H. Barnhart, N. Chalasani   +13 more
semanticscholar   +1 more source

Reducing the Periplasmic Glutathione Content Makes Escherichia coli Resistant to Trimethoprim and Other Antimicrobial Drugs

Microbiology Spectrum, 2021
Although glutathione (GSH) has been shown to influence the antimicrobial effects of many kinds of antibiotics, little is known about its role in relation to trimethoprim (TMP), a widely used antifolate. In this study, several genes related to glutathione
Yajing Song, Zhen Zhou, Jing Gu, Junmei Yang, Jiaoyu Deng   +4 more
doaj   +1 more source

Prevalence of qnrS-positive Escherichia coli from chicken in Thailand and possible co-selection of isolates with plasmids carrying qnrS and trimethoprim-resistance genes under farm use of trimethoprim

Poultry Science, 2022
: One hundred and twenty chicken samples from feces (n = 80), the carcass surface at slaughter at 2 meat chicken farms (n = 20), and retail chicken meat from 5 markets (n = 20) collected during 2018 and 2019 were examined for the prevalence of plasmid ...
Toshiyuki Murase, Patchara Phuektes, Hiroichi Ozaki, Sunpetch Angkititrakul   +3 more
doaj   +1 more source

Photocatalytic degradation of trimethoprim using S-TiO2 and Ru/WO3/ZrO2 immobilized on reusable fixed plates

Journal of Water Process Engineering, 2020
In this study, photocatalytic degradation of trimethoprim by synthesized S-TiO2 and Ru/WO3/ZrO2 catalysts was investigated. Both photocatalysts have been immobilized on circular aluminum plates by polysiloxane to investigate their reusability performance.
M. Samy, Mona G. Ibrahim, M. G. Alalm, M. Fujii, S. Ookawara, T. Ohno   +5 more
semanticscholar   +1 more source

Oral β-Lactam Antibiotics vs Fluoroquinolones or Trimethoprim-Sulfamethoxazole for Definitive Treatment of Enterobacterales Bacteremia From a Urine Source

JAMA Network Open, 2020
Key Points Question Are mortality and recurrent bacteremia different for patients who receive oral β-lactam antibiotics vs fluoroquinolones or trimethoprim-sulfamethoxazole for definitive treatment of Enterobacterales bacteremia from a urinary source ...
J. Sutton, V. Stevens, Nai-Chung N Chang, K. Khader, T. Timbrook, E. Spivak   +5 more
semanticscholar   +1 more source

Synthesis and characterization of mixed Amides-Imines and Amides-Azo Compound derived from Chrysanthemic acid and trimethoprim and study their biological activities [PDF]

مجلة جامعة الانبار للعلوم الصرفة, 2017
Chrysanthemic acid, Trimethoprim, amides, Imines and azo compound : all found to have enormous biological activities in different directions such as medical , pharmaceutical pesticidal …etc.
Mohammad F. Mesher, Barram A. Hama, Balqes A. Ahmed   +2 more
doaj   +1 more source