This review proposes Advance Microbiota Transplantation (AMT), a pre‐peri‐post transplant ‘addition–subtraction’ framework that integrates donor–recipient optimisation, product engineering, and post‐transplant recipient adjuvant management to enhance conventional FMT efficacy and mitigate its limitations. ABSTRACT Faecal microbiota transplantation (FMT)
Haojia Lin +17 more
wiley +1 more source
Elevated serum trimethylamine N-oxide (TMAO) and trimethyllysine in patients with amyotrophic lateral sclerosis (ALS): An exploratory case-control study. [PDF]
Sotgia S +14 more
europepmc +1 more source
Monooxygenase-dehydrogenase cascade for sustained enzymatic remediation of TMA in salmon protein hydrolysates. [PDF]
Ree R +7 more
europepmc +1 more source
Molecular basis of antibiotic sensing by the TetR family regulator CecR – a structural perspective
Escherichia coli CecR, a member of the TetR family regulators, senses selected antibiotics and activates the expression of a putative drug efflux pump. Although present in many pathogenic Enterobacteriales strains, CecR remains poorly characterized. We present the first CecR crystal structure, which reveals a unique tunnel‐like ligand‐binding cavity ...
Agnieszka J. Pietrzyk‐Brzezinska +5 more
wiley +1 more source
Associations of trimethylamine N-oxide (TMAO) and its precursors with childhood obesity: a case-control study. [PDF]
Li Y +7 more
europepmc +1 more source
Bifidobacterium bifidum G9‐1 improved stool form, defecation frequency, and Quality of Life in patients with type 2 diabetes mellitus and chronic kidney disease complicated by constipation. ABSTRACT Introduction Although constipation is a major complication of type 2 diabetes mellitus and chronic kidney disease, evidence for its treatment in these ...
Fuki Ikeda +10 more
wiley +1 more source
Gut and Heart Axis Affects Cardiometabolic Health Through the Ages. A Special Focus on Adolescence. [PDF]
Salzano A, Cittadini A.
europepmc +1 more source
Bacterial Extracellular Vesicles in the Pathogenesis and Treatment of Liver Diseases
Liver diseases are a major global health challenge, with current treatments inadequate. This review highlights the role of bacterial extracellular vesicles in liver inflammation, fibrosis, and metabolism. We also explore these from commensals and probiotics, their protective effects, and discuss research challenges and future therapeutic potential ...
Yakun Li +3 more
wiley +1 more source
Gut microbe-derived trimethylamine shapes circadian rhythms through the host receptor TAAR5. [PDF]
Mahen KK +26 more
europepmc +1 more source
Dietary interventions showed the strongest evidence for improving microbiome composition. Probiotics and prebiotics consistently increased beneficial bacteria. Exercise and fecal microbiota transplantation had limited evidence but showed potential for microbiome modulation.
Yee Teng Lee +6 more
wiley +1 more source

