Results 11 to 20 of about 6,074 (266)

Impact of Immune Checkpoint Inhibitors on Second Primary Cancer Risk in Patients With Metastatic Lung Cancer Using Real-World Data From the TriNetX Network: Retrospective Cohort Study. [PDF]

JMIR Cancer
Heudel P, Hernandez G, Denquin O, Crochet H, Blay JY.   +4 more
europepmc   +2 more sources

Comparison of five-year survival rates among patients with oral squamous cell carcinoma with and without association with syphilis: a retrospective case-control study [PDF]

, 2022
Background: Syphilis is an infectious disease that is at least discussed to be premalignant. This potential, combined with its general pathological impact, raises the question if syphilis increases mortality in oral cancer patients.
Dommisch, Henrik, Hagedorn, Leonie, Heiland, Max, Hertel, Moritz, Preissner, Robert, Preissner, Saskia, Schmidt-Westhausen, Andrea Maria   +6 more
core   +1 more source

Changes in Hematologic Lab Measures Observed in Patients with Paroxysmal Nocturnal Hemoglobinuria Treated with C5 Inhibitors, Ravulizumab and Eculizumab: Real-World Evidence from a US Based EMR Network

Hematology Reports, 2023
Paroxysmal nocturnal hemoglobinuria (PNH), a rare acquired hematologic disorder, can be treated with C5 inhibitors (C5i) such as eculizumab or ravulizumab.
Jesse Fishman, Seth Kuranz, Michael M. Yeh, Kaylen Brzozowski, Herman Chen   +4 more
doaj   +1 more source

A pancreatic cancer risk prediction model (Prism) developed and validated on large-scale US clinical dataResearch in context

EBioMedicine, 2023
Summary: Background: Pancreatic Duct Adenocarcinoma (PDAC) screening can enable early-stage disease detection and long-term survival. Current guidelines use inherited predisposition, with about 10% of PDAC cases eligible for screening.
Kai Jia, Steven Kundrot, Matvey B. Palchuk, Jeff Warnick, Kathryn Haapala, Irving D. Kaplan, Martin Rinard, Limor Appelbaum   +7 more
doaj   +1 more source

A retrospective case–control study for the comparison of 5-year survival rates: the role of adjuvant and neoadjuvant chemotherapy in craniofacial bone sarcoma in adults [PDF]

, 2023
Background: The impact of adjuvant or neoadjuvant chemotherapy in the treatment of craniofacial bone sarcomas has not been clarified. This study aimed to assess whether survival outcomes differed between patients who underwent adjuvant or neoadjuvant ...
Flörcken, Anne, Heiland, Max, Hertel, Moritz, Hofmann, Elena, Preissner, Robert, Preissner, Saskia, Rendenbach, Carsten   +6 more
core   +1 more source

Comparing Surgical Site Occurrences in 1 versus 2-stage Breast Reconstruction via Federated EMR Network

Plastic and Reconstructive Surgery, Global Open, 2021
Background:. TriNetX (TriNetX Inc., Cambridge, Mass.) is a federated electronic medical record network. The TriNetX system conducts customized search queries of over 36 million electronic medical records, and returns results in just minutes. To our group’
Devinder Singh, MD, Benjamin R. Slavin, BS, Tripp Holton, MD   +2 more
doaj   +1 more source

Response to: Query Design Logic in TriNetX Studies [PDF]

Health Science Reports
Robert J. Trager, Zachary A. Cupler, Jordan A. Gliedt, Ryan A. Fischer, Roshini Srinivasan, Hannah Thorfinnson   +5 more
doaj   +2 more sources

Clinical Characteristics and Outcomes of Chagas Disease in the United States: A Multicenter Retrospective Analysis [PDF]

, 2023
Chagas disease affects approximately 300,000 patients in the United States. We evaluated a multicenter U.S.-based network to obtain clinical characteristics and outcomes of chronic Chagas disease by disease forms.
Agudelo-Higuita, Nelson, Chastain, Daniel B., Ferraz, Carolina, Franco-Paredes, Carlos, Henao-Martinez, Andres F., Olivo-Freites, Christian, Rassi Jr., Anis, Tuells, José, Villalpando-Carrión, Salvador, Woc-Colburn, Laila   +9 more
core   +1 more source

Diabetes Mellitus Type 2 as a Risk Factor and Outcome Modifier for Cryptococcosis in HIV Negative, Non-transplant Patients, a Propensity Score Match Analysis [PDF]

, 2023
Cryptococcosis is an opportunistic fungal infection of worldwide distribution with significant associated morbidity and mortality. HIV, organ transplantation, malignancy, cirrhosis, sarcoidosis, and immunosuppressive medications are established risk ...
Chastain, Daniel B., Ferraz, Carolina, Franco-Paredes, Carlos, Henao-Martinez, Andres F., Kennis, Matthew, Kung, Vanessa M., Shapiro, Leland, Thompson III, George R., Tuells, José, Vargas Barahona, Lilian   +9 more
core   +1 more source

Atrial Fibrillation in Patients With Cardiomyopathy: Prevalence and Clinical Outcomes From Real‐World Data

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021
Background Cardiomyopathy is a common cause of atrial fibrillation (AF) and may also present as a complication of AF. However, there is a scarcity of evidence of clinical outcomes for people with cardiomyopathy and concomittant AF. The aim of the present
Benjamin J. R. Buckley, Stephanie L. Harrison, Dhiraj Gupta, Elnara Fazio‐Eynullayeva, Paula Underhill, Gregory Y. H. Lip   +5 more
doaj   +1 more source