A retrospective case–control study for the comparison of 5-year survival rates: the role of adjuvant and neoadjuvant chemotherapy in craniofacial bone sarcoma in adults [PDF]
, 2023 Background: The impact of adjuvant or neoadjuvant chemotherapy in the treatment of craniofacial bone sarcomas has not been clarified. This study aimed to assess whether survival outcomes differed between patients who underwent adjuvant or neoadjuvant ...
Flörcken, Anne +6 more
core +1 more source
Plastic and Reconstructive Surgery, Global Open, 2021 Background:. TriNetX (TriNetX Inc., Cambridge, Mass.) is a federated electronic medical record network. The TriNetX system conducts customized search queries of over 36 million electronic medical records, and returns results in just minutes. To our group’
Devinder Singh, MD +2 more
doaj +1 more source
Clinical Characteristics and Outcomes of Chagas Disease in the United States: A Multicenter Retrospective Analysis [PDF]
, 2023 Chagas disease affects approximately 300,000 patients in the United States. We evaluated a multicenter U.S.-based network to obtain clinical characteristics and outcomes of chronic Chagas disease by disease forms.
Agudelo-Higuita, Nelson +9 more
core +1 more source
Diabetes Mellitus Type 2 as a Risk Factor and Outcome Modifier for Cryptococcosis in HIV Negative, Non-transplant Patients, a Propensity Score Match Analysis [PDF]
, 2023 Cryptococcosis is an opportunistic fungal infection of worldwide distribution with significant associated morbidity and mortality. HIV, organ transplantation, malignancy, cirrhosis, sarcoidosis, and immunosuppressive medications are established risk ...
Chastain, Daniel B. +9 more
core +1 more source
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021 Background Cardiomyopathy is a common cause of atrial fibrillation (AF) and may also present as a complication of AF. However, there is a scarcity of evidence of clinical outcomes for people with cardiomyopathy and concomittant AF. The aim of the present
Benjamin J. R. Buckley +5 more
doaj +1 more source
Sex and age effects on risk of non-traumatic subarachnoid hemorrhage: retrospective cohort study of 124,234 cases using electronic health records [PDF]
, 2023 Objectives: The epidemiology of non-traumatic subarachnoid hemorrhage (SAH) is unclear. This study describes the antecedent characteristics of SAH patients, compares the risk of SAH between women and men, and explores if this changes with age.
Harrison, Charlotte +4 more
core +2 more sources
Onset and recurrence of psychiatric disorders associated with anti-hypertensive drug classes
Translational Psychiatry, 2021 The major anti-hypertensive (AHT) drug classes have been associated with differential risks of psychiatric disorders. However, existing data are limited largely to depression, and confounding variables have not always been controlled for.
Lucy Colbourne +2 more
doaj +1 more source
Effect of Hormone Replacement Therapy on Liver and Cardiometabolic Outcomes in Peri-Menopausal MASLD. [PDF]
Liver IntABSTRACT Background Metabolic dysfunction‐associated steatotic liver disease (MASLD) is the most common chronic liver disease globally. Menopause is associated with increased hepatic fat deposition and thus metabolic dysfunction, contributing to heightened risk of progressive liver and cardiovascular disease.
Henney AE +4 more
europepmc +2 more sources
Antibiotics Significantly Decrease the Survival of Head and Neck Carcinoma Patients with Immunotherapy: A Real-World Analysis of More Than 3000 Cases [PDF]
, 2023 Simple Summary: It is well known that antibiotics alter the gut microbiome, and because it plays a role in drug metabolism, alterations to the microbiome may lead to ineffective immunotherapy in cancer patients.
Heiland, Max +4 more
core +1 more source
Using real-world evidence data and digital monitoring to analyze the hepatotoxic profiles of biologics across more than two million patients [PDF]
, 2023 The real-world evidence data from multiple sources which includes information on patient health status and medical behavior in routine clinical setup can give deeper insights into drugs 'safety and efficacy.
Banerjee, Priyanka +2 more
core +1 more source