Results 41 to 50 of about 6,155 (206)

Could calcitonin gene‐related peptide inhibitors prevent status epilepticus?

Epilepsia, EarlyView.
Abstract Calcitonin gene‐related peptide (CGRP) inhibitors modulate pain and neuroinflammation, a recognized contributor to epileptogenesis and status epilepticus (SE). We examined the association between CGRP inhibitor use and SE hospitalization in epilepsy patients with comorbid migraine.
Michael Nsaka, Noor Baban, Sepideh Allahdadian, Armin Scheffler, Diana Lindner, Dagny Holle, Alain Lekoubou   +6 more
wiley   +1 more source

Predicting Oral Cancer From Precursor Lesions: The Case for a Standardized Framework of Analysis to Improve Prediction Modeling

Head &Neck, EarlyView.
ABSTRACT Oral Cancer often occurs from the transformation of precursor lesions, and this offers an opportunity for early detection. Current methods to assess risk of precursor lesion progression to oral cancer incompletely predict risk. A multimodal framework that leverages machine learning is needed to improve prediction.
Michael E. Troka, James C. Gates
wiley   +1 more source

Association of Glucagon‐Like Peptide—1 Receptor Analogues and Laryngeal Symptoms in Obese Adults

The Laryngoscope, EarlyView.
Table 1 succinctly quantifies the time‑dependent association between GLP‑1RA/GIP therapy and laryngeal symptoms, demonstrating modest but statistically robust increases in outcomes such as cough and voice/resonance disorders by 6 months. It provides clinically actionable absolute risks, odds ratios, and hazard ratios that can directly inform counseling,
Priyanka Shah, David Kayekjian, Shaun A. Nguyen, Kirsten Meenan, Ashli K. O’Rourke   +4 more
wiley   +1 more source

Adjuvant HPV Vaccination and Survival in Oropharyngeal Squamous Cell Carcinoma: An Exploratory Analysis of a Real-World Database. [PDF]

Laryngoscope Investig Otolaryngol
HPV vaccination after exposure may confer survival benefits in oropharyngeal cancer patients. Survival advantages appeared regardless of vaccination timing relative to diagnosis, though small sample sizes preclude definitive conclusions. ABSTRACT Objective Childhood HPV vaccination reduces oropharyngeal cancer (OPC) incidence, but evidence regarding ...
Kim ME, Herrera K, Han A, Hur K, Kokot N, Swanson MS.   +5 more
europepmc   +2 more sources

Radiofrequency Ablation as a Safe and Effective Treatment for Thyroid Nodules After Lobectomy

The Laryngoscope, EarlyView.
ABSTRACT Background A new symptomatic nodule may develop or a preexisting nodule may grow to warrant treatment in the remaining lobe of patients who previously had a unilateral thyroid lobectomy. Conventional management often results in completion thyroidectomy, but radiofrequency ablation (RFA) offers a minimally invasive alternative to surgical ...
Yaser Bashumeel, Mohamad Alsbei, Eli Tsakiris, Sanajana Ratakonda, Sriti Donthi, Amanda Bartolini, Yousef Zenah, Samer Rajjoub, Mohamed Shama, Gregory Randolph, Grace S. Lee, Emad Kandil   +11 more
wiley   +1 more source

Racial and Ethnic Disparities in Facial Paralysis: Diagnosis, Comorbidities, and Chemodenervation

The Laryngoscope, EarlyView.
ABSTRACT Objectives Facial paralysis (FP) is associated with significant functional and psychosocial morbidity, yet potential racial and ethnic disparities in its diagnosis, associated comorbidities, and treatment patterns remain poorly characterized.
Amy Wang, Alexander J. Barna, Eric X. Wei, Scott J. Stephan, Priyesh N. Patel, Shiayin F. Yang   +5 more
wiley   +1 more source

134 Value of TriNetX national database to inform characteristics of observation patients assessed for acute syncope

Journal of Clinical and Translational Science
Objectives/Goals: Syncope is a common diagnosis in observation medicine, and characterization of observation patients is often limited to single unit, single center, or single payer systems.
Megan Donohue, Lisa H. Merck, Sreedhatri Kandlakunta   +2 more
doaj   +1 more source

Trends in Management of Ménière Disease: A TriNetX Network Database Analysis

OTO Open
AbstractThis study investigated management practices for Meniere's disease (MD) and their temporal trends from 2008 to 2022 within the TriNetX network database. Study cohort included adult patients (≥18 years) with the diagnosis of MD from TriNetX's multi‐institutional medical records (n = 77,493).
Tyler J. Gallagher, Meredith E. Adams, Janet S. Choi   +2 more
openaire   +3 more sources

Association of Depression and Anxiety With Postoperative Complications After Septoplasty With Turbinoplasty

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objectives Evaluate the association between comorbid depression and anxiety and postoperative complications following septoplasty with turbinoplasty, and assess whether treatment of these conditions influences surgical outcomes. Study Design Retrospective cohort study with propensity‐score matched analysis. Setting Multi‐institutional database
Amala Nayak, Iman Adibi, Suhas Rao Velichala, Michael F. Armstrong, Theodore Schuman   +4 more
wiley   +1 more source

Real-world outcomes of above-knee amputation: Investigating the impact of peripheral arterial disease

JVS-Vascular Insights
Objective: Above-knee amputation (AKA), or transfemoral amputation, represents a highly morbid surgical procedure, typically performed in patients with irreversible limb compromise due to peripheral arterial disease, diabetes, trauma, or malignancy ...
Micah Thomas, BS, Aaron Ebeweber, MS, Maham Rahimi, MD, PhD   +2 more
doaj   +1 more source