Results 61 to 70 of about 6,155 (206)

The trends and outcomes of inflammatory bowel disease surgery during the COVID‐19 pandemic: A retrospective propensity score‐matched analysis from a multi‐institutional research network

Health Science Reports
Background and Aims The coronavirus disease 2019 (COVID‐19) pandemic has affected the management of inflammatory bowel disease (IBD) patients. Elective operations and surveillance endoscopies were postponed for IBD patients to preserve healthcare ...
Fiona Wu, Gema H. Ibarburu, Caris Grimes
doaj   +1 more source

Elevated lymphoma risk in patients with chronic pruritus and chronic prurigo

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background and objectives Chronic pruritus (CP) and chronic prurigo (CPG, including prurigo nodularis) are prevalent, debilitating diseases with diverse comorbidities, including malignancies. This retrospective cohort study evaluated the prevalence and risk of lymphoma in CP and CPG patients, including key risk factors, and sex‐ and ancestry ...
Svenja Royeck, Henning Olbrich, Steffen Koschmieder, Claudia Zeidler, Felix Witte, Konstantin Agelopoulos, Henning Wiegmann, Michael Storck, Johannes Benedict Oehm, Ralf J. Ludwig, Sonja Ständer   +10 more
wiley   +1 more source

Progression to type 1 diabetes across the autoimmunity and glycaemia continuum: Insights from real‐world paediatric and adult cohorts

Diabetic Medicine, EarlyView.
Abstract Background Type 1 diabetes (T1D) follows a staged autoimmune natural history, yet most evidence describing progression derives from highly selected, genetically at‐risk cohorts. Methods Using the TriNetX Network, we identified eight cohorts of autoantibody‐positive individuals without prior T1D. Four cohorts had preserved glycaemia (HbA1c ≤5.6%
Matthew Anson, Sizheng S. Zhao, Ying Gao, Yang Zhang, Shazli Azmi, Daniel J. Cuthbertson, Ahmed Iqbal, Uazman Alam   +7 more
wiley   +1 more source

SGLT2 Inhibitors and Cardiovascular Outcomes in Patients With Fabry Disease: Observations From a Federated Research Network

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Background and Aim Fabry disease (FD) is frequently complicated by renal impairment and cardiovascular events; however, evidence on sodium–glucose cotransporter‐2 inhibitors (SGLT2i) in this population is scarce. Accordingly, we assessed the association between SGLT2i exposure and cardiovascular outcomes in adults with FD. Methods We conducted
Leandra Serio, Michele Rossi, Amir Askarinejad, Enrico Tartaglia, Tommaso Bucci, Enrica Marrone, Dinesh K. Kalra, Claudio Ferri, Gregory Y. H. Lip   +8 more
wiley   +1 more source

Patient factors associated with tracheoesophageal prosthesis complications: A retrospective TriNetX study

American Journal of Otolaryngology
Tracheoesophageal puncture (TEP) with voice prothesis placement is a common method for voice restoration following total laryngectomy (TL). This study aims to determine patient factors associated with the need for more frequent TEP changes and maintenance in addition to TEP-associated complications.Patients who underwent TEP procedure were identified ...
Sandhya, Ganesan, Sofia A, Finestone, Sana, Smaoui, Timothy Brandon, Shaver, Jennifer, Schottler, Punam, Thakkar, Arjun, Joshi   +6 more
openaire   +2 more sources

Effectiveness of Adding GLP‐1 Receptor Agonists to SGLT2 Inhibitor Therapy in Chronic Kidney Disease: A Population Based Study

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Background Individually, sodium–glucose co‐transporter‐2 inhibitors (SGLT2i) and glucagon‐like peptide‐1 receptor agonists (GLP‐1RAs) have been shown to reduce major kidney and cardiovascular events in patients with chronic kidney disease (CKD). However, evidence supporting combined GLP‐1RA and SGLT2i therapy in this population remains limited.
Hussain Salim, Shaheer Qureshi, Gaurav S. Gulsin, Habib R. Khan, Saad Ahmed Waqas, Gerry P. McCann, Amit Garg, Mohammed Shurrab, Kamlesh Khunti, Muhammad Rashid   +9 more
wiley   +1 more source

Kidney Outcomes With GLP‐1 Receptor Agonists and Tirzepatide Versus Finerenone in Type 2 Diabetes and Chronic Kidney Disease: A Real‐World Cohort Study

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aim To compare kidney outcomes after GLP‐1 receptor agonists (RA) or tirzepatide (GLP‐1/GIP RAs) versus finerenone initiation in adults with Type 2 diabetes (T2D) and moderate chronic kidney disease (CKD). Methods In a retrospective TriNetX global network study (July 2021–November 2025), adults with T2D and CKD stages 3–4 initiating GLP‐1/GIP ...
Dvora R. Sehtman‐Shachar, Alisa Fishkin, Gil Leibowitz, Ofri Mosenzon, Meir Schechter, Genya Aharon‐Hananel   +5 more
wiley   +1 more source

GLP‐1 Receptor Agonist Therapy Is Associated With Lower Risk of Lower Extremity Amputation in Adults With Type 2 Diabetes and Foot Ulcer Without Coded Peripheral Arterial Disease: A Hypothesis‐Generating Real‐World Cohort Study

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims To compare lower extremity amputation (LEA) risk in adults with Type 2 diabetes and diabetic foot ulcer (DFU) treated with glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) versus other glucose‐lowering therapy, and to test whether coded peripheral arterial disease (PAD) modifies this association and replicates across comparator ...
Hani Robinson, Mustafa Yassin, Dror Robinson, Mohamad Eisa, Waseem Abu Rashed, Feras Qawasmi, Assil Mahamid, Hamza Murad, Muhammad Khatib   +8 more
wiley   +1 more source

Pulmonary Vein Isolation Alone Versus Adjunctive Ablation for Paroxysmal Atrial Fibrillation

Journal of Cardiovascular Electrophysiology, EarlyView.
Clinical Outcomes of Pulmonary Vein Isolation Alone Versus Additional Lesion Sets in Paroxysmal Atrial Fibrillation ABSTRACT Background Pulmonary vein isolation (PVI) is the standard ablation strategy for paroxysmal atrial fibrillation (PAF). Despite guideline recommendations favoring PVI alone in PAF, some operators routinely perform extra pulmonary ...
Michel Abou Khalil, Christian M. Massad, Eli Tsakiris, William Herbst, Maximilian Moersdorf, Mohammad Montaser Atasi, Yara Menassa, Alex El Darzi, Carlo El Khoury, Ghassan Bidaoui, Hadi Younes, Yishi Jia, Rodolfo Montiel, Amitabh Pandey, Han Feng, Qussay Marashly, Nassir F. Marrouche, Omar Kreidieh   +17 more
wiley   +1 more source

Type 1 diabetes in the era of obesity: Pathophysiology and therapeutic implications

Journal of Diabetes Investigation, EarlyView.
ABSTRACT Type 1 diabetes is defined by immune‐mediated beta‐cell failure and dependence on exogenous insulin. That definition is correct, but it may not fully describe many people seen in current clinical practice. Overweight and obesity are now common in type 1 diabetes, leading to variable combinations of high insulin requirement, hypertension ...
Zachary Bloomgarden
wiley   +1 more source