Results 81 to 90 of about 5,693 (231)

The National COVID Cohort Collaborative (N3C): Rationale, design, infrastructure, and deployment [PDF]

, 2021
OBJECTIVE: Coronavirus disease 2019 (COVID-19) poses societal challenges that require expeditious data and knowledge sharing. Though organizational clinical data are abundant, these are largely inaccessible to outside researchers.
et al.,, Haendel, Melissa A, Payne, Philip R O   +2 more
core   +1 more source

Prognostic Impact of New‐Onset Atrial Fibrillation After Cardiac Arrest: Observations From a Federated Research Network

Journal of Cardiovascular Electrophysiology, EarlyView.
ABSTRACT Background Data on adverse events in patients developing atrial fibrillation (AF) after cardiac arrest (CA) are limited. Methods Retrospective analysis using the TriNetX network. Adults (≥ 18 years) with CA (ICD‐10‐CM I46) from 2014 to 2024 were divided into two cohorts: those with new‐onset AF (I48) within 2 days after CA and those without ...
Enrico Tartaglia, Tommaso Bucci, Amir Askarinejad, Michele Rossi, Muath Alobaida, Steven Ho Man Lam, Mert Kaskal, Andrea Galeazzo Rigutini, Shir Lynn Lim, Giuseppe Boriani, Gregory Y. H. Lip   +10 more
wiley   +1 more source

Association of glucagon‐like peptide‐1 receptor agonist use with clinical outcomes in patients with rheumatoid arthritis and type 2 diabetes

Journal of Diabetes Investigation, EarlyView.
This TriNetX (US, 2016–2023) study compared clinical outcomes in patients with rheumatoid arthritis and type 2 diabetes treated with GLP‐1 receptor agonists vs DPP4 inhibitors. ABSTRACT Objectives To evaluate whether glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) are associated with improved survival and renal outcomes in patients with ...
Yu‐Ting Yu, Ying Chun Lee, Yu‐Wei Fang, Wen‐Hui Hsieh, Ming‐Hsien Tsai   +4 more
wiley   +1 more source

Epidemiology of globe injury repair mechanisms in the TriNetX US collaborative network database: retrospective cohort study

BMC Ophthalmology
Background To analyze demographics, incidence, and prevalence of globe injury repair mechanisms in the TriNetX United States population from 2013 to 2023.
Matthew D. Spangler, Nila Kirupaharan, Camellia Edalat, Meghan K. Berkenstock   +3 more
doaj   +1 more source

Racial Disparities in Mood Stabilizer Prescribing in Mania in Nonpsychotic, Hospitalized Patients With Bipolar I Disorder. [PDF]

Objective: To investigate racial disparities in the first-time prescription of mood stabilizers for first-episode mania in nonpsychotic, hospitalized patients with bipolar I disorder, specifically comparing the rates of lithium and valproic acid ...
Entsuah-Boateng, Nana, Khorassani, Farah, Ozaki, Aya, Sayer, Michael   +3 more
core   +1 more source

Long-Term Survival of LVAD Patients – A TriNetX Database Analysis

Background: Donor shortage limits the utilization of heart transplantation making it available for only a fraction of the patients on the transplant wait list. Continuous flow left ventricular assist devices have therefore risen in importance as a standard of care for end-stage heart failure.
Nandini Nair, Balakrishnan Mahesh, Dongping Du   +2 more
openaire   +1 more source

Analyzing clinical laboratory data outcomes in retrospective cohort studies using TriNetX

Biochemia medica
TriNetX, a rapidly growing global network of anonymized patient data, enables clinical researchers to perform large-scale retrospective cohort studies. However, its functionality for querying laboratory data outcomes is significantly constrained, as it only provides the results of the most recent test within a specified observation period. Consequently,
Wang, Joshua, Tsai, Kuo-Wang, Lu, Chien-Lin, Lu, Kuo-Cheng   +3 more
openaire   +2 more sources

Calculus-induced obstructive hydronephrosis and herpes zoster risk: a retrospective analysis of the TriNetX global database

European Journal of Medical Research
Background This study investigates the association between urolithiasis-induced hydronephrosis and the reactivation of herpes zoster (HZ). Methods This retrospective cohort study utilized data from the TriNetX database.
Wen-Che Hsieh, Sheng-You Su, Chun Lee, Chao-Yu Hsu   +3 more
doaj   +1 more source

Large-scale analysis highlights obesity as a risk factor for chronic, non-communicable inflammatory diseases [PDF]

Background Overweight and obesity are a global pandemic, contributing to death and disability-adjusted life-years. Obesity is a major factor in the onset of chronic inflammatory diseases (CIDs).
Bieber, Katja, De Luca, David A, Kridin, Khalaf, Lamprecht, Peter, Laudes, Matthias, Ludwig, Ralf J, Mousavi, Sadegh, Olbrich, Henning, Papara, Cristian, Riemekasten, Gabriele, Schmidt, Enno, Thaci, Diamant, Vorobyev, Artem, Zirpel, Henner   +13 more
core   +1 more source

Cutaneous T‐cell lymphomas and dupilumab for atopic dermatitis: A systematic review and expert consensus

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Systematic review (51 studies; 547 patients) indicates dupilumab may unmask/worsen CTCL (mainly MF/SS). A French Delphi consensus recommends rigorous diagnostic workup, avoiding dupilumab in confirmed CTCL, discontinuing upon diagnosis, and favouring methotrexate or phototherapy.
Florent Amatore, Madeleine Neildez, Adèle de Masson, Maxime Battistella, Marie Tauber, Saskia Ingen‐Housz‐Oro, Catherine Droitcourt, Delphine Staumont‐Sallé, Marie Beylot‐Barry   +8 more
wiley   +1 more source