Results 91 to 100 of about 6,155 (206)

Glucagon‐Like Peptide‐1 Agonists and the Incidence of Atrial Fibrillation in Obese Patients With Heart Failure With Preserved Ejection Fraction and No Diabetes

Journal of Arrhythmia, Volume 42, Issue 5, October 2026.
Among obese, non‐diabetic patients with HFpEF, GLP‐1 RA therapy was not significantly associated with incident atrial fibrillation but was associated with lower all‐cause mortality. Prospective studies are needed to clarify the potential role of GLP‐1 RAs in AF prevention. ABSTRACT Background Glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) reduce
Farah Rassam, Esteban Kosak Lopez, Sarah Sass, Thitiphan Srikulmontri, Evan Isaacs, John Malin, Phuuwadith Wattanachayakul, Olayinka Afolabi‐Brown   +7 more
wiley   +1 more source

Rare But Risky: Clinical Impacts of Pneumothorax After Thyroidectomy and Parathyroidectomy

The Laryngoscope, Volume 136, Issue 10, Page 4589-4595, October 2026.
Postoperative pneumothorax (PPTX) is rare after thyroidectomy or parathyroidectomy, occurring in up to 0.10% of cases. However, it is associated with increased risks of all‐cause mortality, adverse respiratory events, and healthcare utilization rates in up to 1 year after surgery, deeming PPTX as a potential marker of increased postoperative ...
Jessan A. Jishu, Alexandra LaForteza, Dara Bruce, Isabel Riccio, Mina Liao, Yaser Y. Bashumeel, Emad Kandil, Mohamed A. Shama   +7 more
wiley   +1 more source

Risk of uveitis in patients with human immunodeficiency virus: a cohort study through TriNetX database

AIDS Research and Therapy
Background This multi-institutional, retrospective cohort study using TriNetX database aims to explore the relationship between HIV infection and uveitis.
Bing-Qi Wu, Hou-Ting Kuo, Alan Y. Hsu, Yi-Ching Shao, Chun-Ting Lai, Hsin Tseng, Chun-Chi Chiang, Chun-Ju Lin, Ning-Yi Hsia, Huan-Sheng Chen, Yu-Hsun Wang, Yi-Yu Tsai, Min-Yen Hsu, James Cheng-Chung Wei   +13 more
doaj   +1 more source

420 Computable Phenotyping with “Big Data” as a Foundation for Artificial Intelligence Algorithm Construction: Puberty as a Transdisciplinary Case Example

Journal of Clinical and Translational Science
OBJECTIVES/GOALS: Artificial intelligence (AI) depends on quality machine learning (ML) algorithms constructed with high-quality training data. This TL1 trainee project develops a disease-agnostic computable phenotype framework for ML algorithm ...
David (DJ) Schnabel, Lorah D. Dorn
doaj   +1 more source

Risk of systemic rheumatic diseases in people with irritable bowel syndrome: a global-federated cohort analysis

Frontiers in Immunology
BackgroundIrritable bowel syndrome (IBS) is a prevalent disorder of gut–brain interaction increasingly linked to immune and inflammatory dysregulation.
Shuo-Yan Gau, Shuo-Yan Gau, Shuo-Yan Gau, Yu-Jung Su, Shih-Chi Yang, Chien-Chin Chen, Chien-Chin Chen, Chien-Chin Chen, Chien-Chin Chen, Solomon Chih-Cheng Chen, Solomon Chih-Cheng Chen, Hui-Chin Chang, Hui-Chin Chang, Hui-Chin Chang, Meng-Che Wu, Meng-Che Wu, Meng-Che Wu   +16 more
doaj   +1 more source

Long-Term Survival of LVAD Patients – A TriNetX Database Analysis

Background: Donor shortage limits the utilization of heart transplantation making it available for only a fraction of the patients on the transplant wait list. Continuous flow left ventricular assist devices have therefore risen in importance as a standard of care for end-stage heart failure.
Nandini Nair, Balakrishnan Mahesh, Dongping Du   +2 more
openaire   +1 more source

Enhancing the management of acute and gangrenous cholecystitis: a systematic review supported by the TriNetX database

Translational Gastroenterology and Hepatology
Acute cholecystitis (AC) leads to emergency hospital admissions, and is categorized into mild, moderate, or severe grades, and affects hospital stay, surgery rates, costs, and prognosis. Gangrenous cholecystitis (GC) is the severe form and entails gallbladder wall necrosis and infection, possibly leading to emphysematous cholecystitis (EC), a life ...
Fabbri, Nicolò, Greco, Salvatore, Pesce, Antonio, Virgilio, Francesco, Bonazza, Luca, Bagnoli, Luca, Feo, Carlo V.   +6 more
openaire   +2 more sources

15 Discrepancies in Medication Usage and Lifestyle Modification Referrals in Metabolic Syndrome is Dependent on how the Syndrome is Coded: A TriNetX Study

Journal of Clinical and Translational Science
OBJECTIVES/GOALS: ICD-10 coding inconsistencies hinder timely recognition and treatment of metabolic syndrome (MetS), posing a significant risk for cardiometabolic disease progression.
Annabelle N. Brinkerhoff, Jigar Gosalia, Juan J. Qiu, James A. Pawelczyk, David N. Proctor   +4 more
doaj   +1 more source

Assessment of Major Adverse Cardiovascular Event Across Diverse Racial Groups of Psoriasis Patients on Biologic Therapy: A Retrospective Cohort Study

The Journal of Dermatology, Volume 53, Issue 10, Page 1439-1447, October 2026.
ABSTRACT Psoriasis is associated with an increased risk of major adverse cardiovascular events (MACE), and biologic therapy may reduce this risk by targeting systemic inflammation. However, limited data exist on whether long term MACE risk differs by biologic class or across racial groups. We conducted a retrospective cohort study to assess the risk of
Chunghwan Ro, Ana Ormaza Vera, Waleed Adawi, Clinton W. Enos   +3 more
wiley   +1 more source

GLP‐1‐Based Therapies in Type 1 Diabetes: Emerging Evidence on Cardiovascular, Renal, and Safety Outcomes

Diabetes, Obesity and Metabolism, Volume 28, Issue 10, Page 8757-8768, October 2026.
ABSTRACT Background Individuals living with type 1 diabetes (T1D) are at increased risk for cardiovascular (CV) and renal complications, yet therapeutic strategies specifically targeting cardiorenal risk reduction in this population remain limited. The role of glucagon‐like peptide‐1 (GLP‐1)‐based therapies in T1D remains unclear.
Anastasios Tentolouris, Djordje S. Popovic, Alexandros L. Liarakos, Alexandros Briasoulis, Nikolaos Papanas, Theocharis Koufakis   +5 more
wiley   +1 more source