Results 91 to 100 of about 5,693 (231)

Anxiety, Depression, Schizophrenia, and Bipolar Disorder in Eosinophilic Esophagitis Patients: A Global Federated Cohort Analysis of Bidirectional Risks

Allergy, EarlyView.
Hui‐Chin Chang, Meng‐Che Wu, Torsten Zuberbier, Shuo‐Yan Gau   +3 more
wiley   +1 more source

A Systematic Review and Meta‐Analysis of Semaglutide Effects on Adipose Tissue and Emerging Effects on Brain and Cognition

Obesity Reviews, EarlyView.
ABSTRACT Background In 2023 and 2024, research into semaglutide (SEMA), an antiobesity and antidiabetic medication, indicated potential benefits beyond its approved uses, particularly in preventing Alzheimer's disease (AD). This highlights the link between obesity and AD development.
Amene Saghazadeh, Mahsa Dolatshahi, Soheil Mohammadi, Sara Hosseinzadeh Kassani, Mahshid Naghashzadeh, Joseph E. Ippolito, Claude B. Sirlin, Bettina Mittendorfer, Matthew R. Brier, Suzanne E. Schindler, John C. Morris, Danny Mou, Hani Charles Soudah, Tammie L. S. Benzinger, Cyrus A. Raji   +14 more
wiley   +1 more source

Methodology for creating a novel cardiac arrest registry using the Trinetx electronic health record database

Resuscitation Plus
Background: Care in the hospital, post-arrest care, is a crucial component of out-of-hospital cardiac arrest (OHCA) management, but current OHCA databases contain limited post-arrest care data. To address this, we present the methodology for assembling a
Ryan Huebinger, Ryan A. Coute, Larissa Myaskovsky, Cameron Crandall, Ethan Abbott, Keith E. Kocher, Aditya C Shekhar, Benjamin S. Abella   +7 more
doaj   +1 more source

Prevalence of Metabolic-Associated Steatotic Liver Disease in Patients with Type 2 Diabetes with and without HIV: Retrospective Multicenter Study [PDF]

Introduction: Metabolic dysfunction-associated steatotic liver disease (MASLD) is a frequent complication in patients with Type 2 Diabetes (T2D). This study aims to evaluate the impact of HIV status on the prevalence of MASLD in patients with T2D ...
Abosheaishaa, Hazem, Alfishawy, Mostafa, Martinez , Anthony, Nassar, Omar   +3 more
core   +2 more sources

Initial Site of Metastasis Influences Prognosis in Pancreatic Ductal Adenocarcinoma

Cancer Medicine, Volume 15, Issue 4, April 2026.
ABSTRACT Introduction Metastatic pancreatic ductal adenocarcinoma (mPDAC) is a highly aggressive malignancy. Prior studies suggest that the initial site of metastasis may impact prognosis. This study investigates whether overall survival in mPDAC patients differs between patients first presenting with lung metastases versus those presenting with liver ...
Eleanor Mancheski, David Baek, Wilbur Bowne, Harish Lavu, Charles J. Yeo, Avinoam Nevler   +5 more
wiley   +1 more source

GLP‐1 at the Metabolic–Cognitive Interface: Reward, Affect, and Memory

Comprehensive Physiology, Volume 16, Issue 2, April 2026.
GLP‐1R signaling integrates metabolic state with neural circuits controlling reward, mood, and memory, acting as a metabolic‐cognitive interface. In reward pathways, it suppresses hedonic feeding and drug seeking; in affective circuits, sustained signaling promotes anxiolytic and antidepressant effects; and in the hippocampus, it enhances synaptic ...
Serena X. Gao, Léa Décarie‐Spain, Cindy Gu, Giulia Mazzini, Scott E. Kanoski, Tito Borner   +5 more
wiley   +1 more source

Evaluating the Efficacy, Safety, and Practical Considerations of Semaglutide for Weight Loss in Non‐Diabetic Adults: A Narrative Review

Health Science Reports, Volume 9, Issue 4, April 2026.
ABSTRACT Background and Aims The rising global prevalence of obesity has catalyzed the development of potent glucagon‐like peptide‐1 (GLP‐1) receptor agonists. This narrative review evaluates the efficacy, safety, and practical considerations of injectable semaglutide for weight management, specifically in non‐diabetic adults, a population where weight
Ayesha Laraib, Uswa Ahmad, Syeda Iman Laraib, Syeda Wardah Laraib, Masab Ali, Muhammad Husnain Ahmad, Muhammad Hassan   +6 more
wiley   +1 more source

Risk of uveitis in patients with human immunodeficiency virus: a cohort study through TriNetX database

AIDS Research and Therapy
Background This multi-institutional, retrospective cohort study using TriNetX database aims to explore the relationship between HIV infection and uveitis.
Bing-Qi Wu, Hou-Ting Kuo, Alan Y. Hsu, Yi-Ching Shao, Chun-Ting Lai, Hsin Tseng, Chun-Chi Chiang, Chun-Ju Lin, Ning-Yi Hsia, Huan-Sheng Chen, Yu-Hsun Wang, Yi-Yu Tsai, Min-Yen Hsu, James Cheng-Chung Wei   +13 more
doaj   +1 more source

15 Discrepancies in Medication Usage and Lifestyle Modification Referrals in Metabolic Syndrome is Dependent on how the Syndrome is Coded: A TriNetX Study

Journal of Clinical and Translational Science
OBJECTIVES/GOALS: ICD-10 coding inconsistencies hinder timely recognition and treatment of metabolic syndrome (MetS), posing a significant risk for cardiometabolic disease progression.
Annabelle N. Brinkerhoff, Jigar Gosalia, Juan J. Qiu, James A. Pawelczyk, David N. Proctor   +4 more
doaj   +1 more source

Equity in Cystic Fibrosis Care: Addressing Racial Disparities in Cystic Fibrosis Treatment [PDF]

Introduction: Cystic fibrosis (CF) is historically underdiagnosed in Black populations, in part due to symptom misattribution and diagnostic frameworks centered around White patient presentations.
Khan, Manahil
core