Results 71 to 80 of about 5,693 (231)

Assessing Major Adverse Liver Outcomes With Baclofen Compared to Acamprosate in Compensated Alcohol‐Associated Cirrhosis

Alimentary Pharmacology &Therapeutics, EarlyView.
We conducted a nationwide, multicenter cohort study using a target trial emulation framework to compare baclofen and acamprosate in patients with compensated alcohol‐associated cirrhosis. After matching, baclofen initiation was associated with a higher 1‐year risk of major adverse liver outcomes, driven primarily by hepatic encephalopathy, particularly
Yee Hui Yeo, Sepideh Mehravar, Ellen Choi, Ju Dong Yang, Hyun‐Seok Kim, Yun Wang, Aarshi Vipani, Hirsh D. Trivedi, Walid Ayoub, Parnian Naji, Alexander Kuo, Chun‐Ying Wu, Lorenzo Leggio, Juan Pablo Arab   +13 more
wiley   +1 more source

P1747: A REAL-WORLD ANALYSIS OF HEALTHCARE RESOURCE UTILIZATION AMONG PATIENTS WITH PAROXYSMAL NOCTURNAL HEMOGLOBINURIA WHO RECEIVED TREATMENT WITH RAVULIZUMAB

HemaSphere, 2022
J. Fishman, S. Kuranz, M. Yeh, K. Brzozowski, H. Chen   +4 more
doaj   +1 more source

Prevalence of Hepatitis C Virus Among Hospitalized Patients in a Tertiary Hospital in Italy: The Basis for a National Screening Assessment Model?

Microorganisms
Free-of-charge hepatitis C virus antibody (HCV Ab) screening in some key populations and in 1969–1989 birth cohorts have been funded in Italy as the first step in confirming diagnosis in individuals who may be unaware of their infection.
Giulia Morsica, Massimo Locatelli, Gema Hernandez-Ibarburu, Francesca Rusconi, Alba Segovia-Hilara, Davide Di Napoli, Matteo Moro, Salvatore Mazzitelli, Hamid Hasson, Federico Esposti, Roberts Mazzuconi, Antonella Castagna   +11 more
doaj   +1 more source

The rapidly increasing incidence of type 2 diabetes and macrovascular and microvascular complications disproportionately affects younger age groups: A decade of evidence from an international federated database [PDF]

Aims: To characterise recent trends in incidence and prevalence of type 2 diabetes (T2D) associated complications, and their relative impact across the lifespan.
Alam, Uazman, Anson, Matthew, Cuthbertson, Daniel J, Edwards, Harry, Garrib, Anupam, Henney, Alex E, Ibarburu, Gema H, Jaffar, Shabbar, Lip, Gregory YH, Mordi, Ify, Nabrdalik, Katarzyna, Perkins, Bruce A, Wang, Duolao   +12 more
core  

Sodium‐glucose co‐transporter 2 inhibitors and obesity‐associated cancers in people with type 2 diabetes: A real‐world observational study

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Aims To investigate the association between sodium‐glucose co‐transporter 2 inhibitors (SGLT‐2i) and obesity‐associated cancers (OAC) in individuals with type 2 diabetes (T2D). Materials and Methods This retrospective cohort study used data from the TriNetX US Collaborative Network.
Testimony Ipaye, Jonathan Goldney, Thomas Yates, Francesco Zaccardi, Kamlesh Khunti, Elina Akalestou, Melanie J. Davies, Karen Brown, Dimitris Papamargaritis   +8 more
wiley   +1 more source

Dementia Incidence in Patients With Prurigo Nodularis: An Observational Retrospective Cohort Study

JEADV Clinical Practice, EarlyView.
Madison P. Olexson, Ana Ormaza Vera, Chunghwan Ro, Clinton W. Enos   +3 more
wiley   +1 more source

Downstream Treatment Burden and Health‐Care Utilization Following Initiation of GLP‐1 Receptor Agonists or SGLT2 Inhibitors in Type 2 Diabetes

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims Glucagon‐like peptide‐1 (GLP‐1) receptor agonists and sodium–glucose cotransporter 2 (SGLT2) inhibitors are widely used for the treatment of type 2 diabetes, yet their downstream consequences in routine clinical practice remain incompletely characterized.
Yazan Alhamdan, Jason C. Hsu, Christine Y. Lu   +2 more
wiley   +1 more source

The trends and outcomes of inflammatory bowel disease surgery during the COVID‐19 pandemic: A retrospective propensity score‐matched analysis from a multi‐institutional research network

Health Science Reports
Background and Aims The coronavirus disease 2019 (COVID‐19) pandemic has affected the management of inflammatory bowel disease (IBD) patients. Elective operations and surveillance endoscopies were postponed for IBD patients to preserve healthcare ...
Fiona Wu, Gema H. Ibarburu, Caris Grimes
doaj   +1 more source

Raynaud’s phenomenon is associated with an increased risk of cardiovascular disease and venous thromboembolism [PDF]

Objectives: Raynaud's phenomenon (RP) is common affecting 3–5 % of the population; however, there are little data concerning vascular outcomes. We aimed to estimate risk of cardiovascular disease (CVD) and venous thromboembolism (VTE) in individuals with
Alam, Uazman, Hughes, Michael, Jude, Edward, McMahan, Zsuzsanna H., Ruaro, Barbara, Zhao, Sizheng Steven   +5 more
core   +1 more source

Association between red blood cell distribution width and 30-day mortality in critically ill septic patients: a propensity score-matched study

Journal of Intensive Care
Background Sepsis is the leading cause of death worldwide, and a number of biomarkers have been developed for early mortality risk stratification. Red blood cell distribution width (RDW) is a routinely available hematological data and has been found to ...
Yu-Cheng Wu, Hsin-Hua Chen, Wen-Cheng Chao   +2 more
doaj   +1 more source