Production of peptide molecules from hazelnut cake using proteolytic enzymes and ultrafiltration methods. Exploration of antioxidant activities, DPP‐IV and ACE inhibitory properties of these molecules and their evaluation in food supplement applications.
Sebahat Şişman +3 more
wiley +1 more source
Some kinetic, equilibrium, and structural studies of the reactions of aromatic nitro-compounds with nucleophiles [PDF]
Not ...
Gibson, Brenda
core
CAR‐T cell therapy in systemic rheumatic diseases and autoimmune disorders. (This figure was created using BioRender.com.) ABSTRACT Chimeric antigen receptor T (CAR‐T) cell therapy, originally developed for hematologic malignancies, has emerged as a transformative candidate for systemic rheumatic diseases and autoimmune disorders (AIDs).
Zhidan Fan, Li Zhang, Haiguo Yu
wiley +1 more source
Predictive Modeling of Organic Pollutant Leaching and Transport Behavior at the Lysimeter and Field Scales [PDF]
Soil and groundwater pollution has become a global issue since the advent of industrialization and mechanized agriculture. Some contaminants such as PAHs may persist in the subsurface for decades and centuries.
Amankwah, Edward Akwasi
core +2 more sources
Flow Hydrogenation of 1,3,5-Trinitrobenzenes over Cu-Based Catalysts as an Efficient Approach for the Preparation of Phloroglucinol Derivatives [PDF]
An environmentally friendly and safe synthesis of phloroglucinol and its derivatives through the flow hydrogenation of 1,3,5-trinitrobenzenes on heterogeneous copper catalysts is reported.
Alexey L. Nuzhdin +6 more
core +1 more source
The crystal structure of ammelide, also known as melanuric acid, was solved almost 200 years after its discovery by Liebig. Moreover, three modifications of its 1:1 adduct with ammeline were structurally elucidated, consisting of layers with a honeycomb motif analogous to melamine cyanurate.
Thaddäus J. Koller +8 more
wiley +1 more source
Neddylation Targets and Stabilizes NLRP3 to Augment Inflammasome‐Mediated Colitis and Mood Disorder
NLRP3 inflammasome contributes to colitis and mood disorder. This study demonstrates that neddylation targets NLRP3 at K287, which hinders its interaction with K48‐linked ubiquitination E3 Trim31 and thereby stabilizes it. Neddylation blockade in myeloid cells and microglia mitigates DSS‐induced colitis and psychological stress‐induced anxiety‐like ...
Wenbin Gai +13 more
wiley +1 more source
Extracellular Vesicles in Autoimmune Diseases: From Diagnostic Biomarkers to Engineered Therapeutics
This review provides a systematic comparison of extracellular vesicles (EVs) from both mammalian and plant sources in the context of autoimmune diseases. It highlights their emerging roles as precision biomarkers and engineered therapeutic platforms.
Yufei Wu +6 more
wiley +1 more source
Some kinetic and equilibrium studies of σ-adduct formation and proton transfer in the reactions of aromatic nitro-compounds with bases [PDF]
Comparison of kinetic and equilibrium data for the cyclisation of 1-(2,2-dimethyl-3-hydroxypropoxy)-2,4-dinitro- naphthalene in alkaline media with those for the cyclisation of 1-(3-hydroxypropoxy)-2,4-dinitronaphthalene indicates the absence of a marked
Routledge, Paul James
core
From Pharmaceutical to Biophysical Therapies: New Horizons in Inflammatory Bowel Disease Management
Important limitations exist in the current pharmacological landscape of Inflammatory Bowel Disease (IBD), such as variable response rates and treatment‐limiting adverse effects. In this review, we perform a critical assessment of the current literature on novel multimodal biophysical approaches showing alternative mechanisms of action to, and potential
Benedetta Ricchi +7 more
wiley +1 more source

