Results 131 to 140 of about 6,160 (172)

Pea seed triose phosphate isomerase

Phytochemistry, 1979
Abstract Triose phosphate isomerase was purified ca 250-fold from pea seed extracts. The k m for D -glyceraldehyde-3-P was 0.44 mM and for dihydroxyacetone-P, 0.88 mM. P-enolpyruvate, 2-P-glycerate, 3-P-glycerate and 2-P-glycolate were strongly inhibitory. Pi and arsenate also inhibited pea seed triose phosphate isomerase.
John F Turner
exaly   +2 more sources

New inhibitors of rabbit muscle triose-phosphate isomerase

Bioorganic and Medicinal Chemistry Letters, 2005
We describe the synthesis and evaluation of three new competitive inhibitors of triose-phosphate isomerase. One of them (phosphoglycoloamidoxime: K(i) = 4.5 microM) is among the best reversible inhibitors so far reported for this enzyme.
Matthieu Fonvielle
exaly   +3 more sources

Triose phosphate isomerase deficiency: Report of a family

Journal of Paediatrics and Child Health, 1986
AbstractTriose phosphate isomerase (TPI) deficiency is associated with a syndrome of congenital non‐spherocytic haemolytic anaemia, mental subnormality, motor impairment, growth failure and cardiac failure. The deficiency state is characterized by moderately reduced red cell TPI activity, and marked instability of the abnormal enzyme to heat.
A C, Clark, M A, Szobolotzky
exaly   +3 more sources

Triose phosphate isomerase deficiency

Biochemical Medicine, 1977
Abstract Three patients with triose phosphate isomerase deficiency have been studied. 1. (a) A profound deficiency was found in red blood cells, white blood cells, and fibroblasts of the patients. 2. (b) Extracts from leukocytes and fibroblasts showed a marked decrease in thermal stability. 3. (c) The electrophoretic mobility of the major
H, Skala, J C, Dreyfus, J L, Vives-Corrons, F, Matsumoto, E, Beutler   +4 more
openaire   +2 more sources

Prenatal diagnosis of triose phosphate isomerase deficiency

Lancet, The, 1990
A N Lestas
exaly   +2 more sources

PRENATAL DIAGNOSIS OF TRIOSE PHOSPHATE ISOMERASE DEFICIENCY

Lancet, The, 1989
Bruno Dallapiccola, Giuseppe Novelli
exaly   +2 more sources

Isolation of triose phosphate isomerase from the lens

Experimental Eye Research, 1968
The glycolytic enzyme, triose phosphate isomerase, has been purified and crystallized from bovine lens. The lens enzyme resembles the enzyme from rabbit muscle in its catalytic activity, and in its crystalline form. The electrophoretic mobility of the enzyme from bovine lens differs from that of the enzyme from rabbit muscle.
P M, Burton, S G, Waley
openaire   +2 more sources

Triose phosphate isomerase deficiency: Prenatal diagnosis

The Journal of Pediatrics, 1985
A child with triose phosphate isomerase deficiency has congenital nonspherocytic hemolytic anemia, mental subnormality, motor impairment, growth failure, and cardiac failure. The deficiency state is characterized by moderately reduced red cell triose phosphate isomerase activity and marked instability of the abnormal enzyme to heat.
A C, Clark, M A, Szobolotzky
openaire   +2 more sources

Purification and properties of liver triose phosphate isomerase

Biochimica et Biophysica Acta (BBA) - Enzymology, 1971
Abstract Triose phosphate isomerase ( d -glyceraldehyde-3-phosphate ketol-isomerase, EC 5.3.1.1) was prepared from horse and human livers with specific activities of 3 183 and 2 397 I.U./mg, respectively. The molecular weights of the human liver isomerase and the corresponding rabbit muscle enzyme were not significantly different.
E W, Lee, J A, Barriso, M, Pepe, R, Snyder   +3 more
openaire   +2 more sources

Evidence for the activity of immobilised monomers of triose phosphate isomerase

Biochemical and Biophysical Research Communications, 1975
Abstract Chicken muscle triose phosphate isomerase was immobilised by attachment to Sepharose 4B. The immobilised dimeric enzyme was dissociated with guanidinium chloride to yield bound monomeric triose phosphate isomerase. This regained activity on removal of the denaturant, showing that isolated monomers possess activity; the apparent K m of the ...
D A, Fell, C J, White
openaire   +2 more sources