Results 91 to 100 of about 45,786 (250)
Methylglyoxal Produced by Amyloid- Peptide-Induced Nitrotyrosination of Triosephosphate Isomerase Triggers Neuronal Death in Alzheimer’s Disease [PDF]
, 2014 Amyloid-β peptide (Aβ) aggregates induce nitro-oxidative stress, contributing to the characteristic neurodegeneration found in Alzheimer's disease (AD).
Boada, M. +15 more
core +2 more sources
Molecules, 2009 Antitrypanosomal natural products with different structural motifs previously shown to have growth inhibitory activity against Trypanosoma brucei were docked into validated drug targets of the parasite, which include trypanothione reductase, rhodesain ...
William N. Setzer, Ifedayo V. Ogungbe
doaj +1 more source
mBio, 2020 Carbon metabolism plays an essential role in bacterial pathogenesis and susceptibility to antibiotics. In Pseudomonas aeruginosa, Crc, Hfq, and a small RNA, CrcZ, are central regulators of carbon metabolism.
Yushan Xia +12 more
doaj +1 more source
Molecular Ecology, Volume 34, Issue 15, August 2025.ABSTRACT Social insects form complex societies with division of labour between different female castes. In most species, a single queen heads the colony; in others, several queens share the task of reproduction. These different social organisations are often associated with distinct queen morphologies and life‐history strategies and occur in different ...
Marah Stoldt +3 more
wiley +1 more source
Analysis of the proteome and the secretome of animal trypanosomes : a standardized analytical method to look for new molecular targets [PDF]
, 2007 The causative agents of animal trypanosomosis are various species of protozoan parasites belonging to the genus Trypanosoma, among which T. congolense and T. evansi are the major pathogenic species. The extra cellular position of the trypanosomes implies
Bengaly, Zakaria +10 more
core
Label-free shotgun proteomics and metabolite analysis reveal a significant metabolic shift during citrus fruit development. [PDF]
, 2011 Label-free LC-MS/MS-based shot-gun proteomics was used to quantify the differential protein synthesis and metabolite profiling in order to assess metabolic changes during the development of citrus fruits.
Blumwald, Eduardo +8 more
core +3 more sources
Biotechnology Reports, 2017 Rare arginine codons AGA and AGG affect the heterologous expression of proteins in Eschericha coli. The tRNAs necessary for protein synthesis are scarce in E. coli strain BL21(DE3) pLysS and plentiful in strain BL21(DE3) CodonPlus −RIL.
Beatriz Aguirre-López +4 more
doaj +1 more source
Ecology and Evolution, Volume 15, Issue 7, July 2025.The vast Lake Baikal in Siberia is located in a region with a continental climate, implying pronounced seasonal temperature differences. Remarkably, reproducing during the extremely cold winters when the lake is covered by a thick ice layer is a common trait in Baikal's endemic littoral amphipods.
Polina Lipaeva +6 more
wiley +1 more source
Journal of Orthopaedic Research, Volume 43, Issue 7, Page 1239-1249, July 2025.ABSTRACT Posttraumatic osteoarthritis (PTOA) is a common sequela to anterior cruciate ligament (ACL) injury in humans and dogs. Identification of conserved targets between species may hasten biomarker identification and therapeutic development. To identify differentially regulated synovial fluid (SF) proteins in ACL injury, SF samples were collected ...
Sydney J. Womack +4 more
wiley +1 more source
Plant Direct, Volume 9, Issue 7, July 2025.ABSTRACT The apoplastic space surrounding plant cells, encompassing the cell wall matrix, extracellular spaces, and xylem, is one of the least understood compartments within plant tissues due to its lack of limiting membranes and its unavoidable damage upon tissue homogenization. Using a streamlined vacuum‐infiltration/centrifugation protocol to enrich
Kuo‐En Chen +2 more
wiley +1 more source