Results 91 to 100 of about 18,060 (230)

Top‐Down Proteomics Study of Aging and Sexual Dimorphism of Zebrafish Brains

Journal of Mass Spectrometry, Volume 61, Issue 1, January 2026.
ABSTRACT Aging significantly impacts brain function and increases susceptibility to neurodegenerative diseases, with notable sex dimorphism observed in aging‐related dementia, such as Alzheimer's disease. To better understand the molecular mechanisms of aging and dementia, it is essential to globally and accurately characterize biomolecules (e.g ...
Mehrdad Falamarzi Askarani, William Poulos, Maryam Rahimzadeh Dashtaki, Seyed Amirhossein Sadeghi, Jose B. Cibelli, Fei Fang, Liangliang Sun   +6 more
wiley   +1 more source

Structure of triosephosphate isomerase fromCryptosporidium parvum [PDF]

Acta Crystallographica Section F Structural Biology and Crystallization Communications, 2011
Cryptosporidium parvum is one of several Cryptosporidium spp. that cause the parasitic infection cryptosporidiosis. Cryptosporidiosis is a diarrheal infection that is spread via the fecal-oral route and is commonly caused by contaminated drinking water.
Nguyen, Trang N., Abendroth, Jan, Leibly, David J., Le, Kristen P., Guo, Wenjin, Kelley, Angela, Stewart, Lance, Myler, Peter J., Van Voorhis, Wesley C.   +8 more
openaire   +2 more sources

Detection of Cryptosporidium and Giardia duodenalis in Reptiles in Thailand

Veterinary Medicine and Science, Volume 12, Issue 1, January 2026.
ABSTRACT Cryptosporidium spp. and Giardia duodenalis are significant intestinal protozoan parasites affecting humans and animals worldwide. These infections are transmitted through the faecal–oral route, by contaminated water, food or close contact with infected hosts.
Chantira Sutthikornchai, Ai‐Rada Pintong, Ruenruetai Udonsom, Tachin Khulmanee, Rachatawan Chiabchalard, Aongart Mahittikorn, Weerapun Nokkaew, Jitbanjong Toompong, Supaluk Popruk, Christen Rune Stensvold   +9 more
wiley   +1 more source

Purification and Partial Characterization of Trypanosoma cruzi Triosephosphate Isomerase

Memorias do Instituto Oswaldo Cruz, 1998
The enzyme triosephosphate isomerase (TPI, EC 5.3.1.1) was purified from extracts of epimastigote forms of Trypanosoma cruzi. The purification steps included: hydrophobic interaction chromatography on phenyl-Sepharose, CM-Sepharose, and high performance ...
Bourguignon SC, Meirelles MN, Pacheco RS, De Simone S Giovanni   +3 more
doaj  

Analysis of the proteome and the secretome of animal trypanosomes : a standardized analytical method to look for new molecular targets [PDF]

, 2007
The causative agents of animal trypanosomosis are various species of protozoan parasites belonging to the genus Trypanosoma, among which T. congolense and T. evansi are the major pathogenic species. The extra cellular position of the trypanosomes implies
Bengaly, Zakaria, Boulangé, Alain, Brizard, Jean-Paul, Courtois, Pierrette, Cuny, Gérard, Daulouède, Sylvie, Frutos, Roger, Grébaut, Pascal, Holzmuller, Philippe, Peltier, Jean-Benoît, Vincendeau, Philippe   +10 more
core  

Animals and Fungi are Each Other's Closest Relatives: Congruent Evidence from Multiple Proteins [PDF]

, 1993
Phylogenetic relationships among plants, animals, and fungi were examined by using sequences from 25 proteins. Four insertions/deletions were found that are shared by two of the three taxonomic groups in question, and all four are uniquely shared by ...
Baldauf, S.L., Palmer, J.D.
core   +2 more sources

Experimental Evidence That Prenatal and Postnatal Developmental Stress Affects the Adult Seminal Fluid Proteome in a Precocial Bird

Molecular Ecology, Volume 35, Issue 2, January 2026.
ABSTRACT Seminal fluid proteins are important modulators of male fertility and reproductive success, yet little is known about how their abundance responds to early‐life developmental stress. Japanese quail Coturnix japonica) males produce a unique seminal foam that enhances fertilisation success.
Chloe Mason, Martin Garlovsky, Oscar Vedder, Trong Khoa Pham, Rachel George, Barbara Tschirren, Nicola Hemmings   +6 more
wiley   +1 more source

Multi‐Omic Analysis of Scylla serrata Reveals the Allergen Landscape of Mud Crabs and Decapoda Species

Allergy, EarlyView.
Kelvin Fu‐Kiu Ao, Judy Kin Wing Ng, Cherie Tsz‐Yiu Law, Weixue Mu, Shanshan Li, Christine Yee Yan Wai, Man Fung Tang, Shannon Wing Ngor Au, Xiaoyu Liu, Ting Fan Leung, Qing Xiong, Stephen Kwok‐Wing Tsui   +11 more
wiley   +1 more source

Rational Design of Novel Inhibitors: Integrating 3D‐QSAR and Molecular Dynamics

BioMed Research International, Volume 2026, Issue 1, 2026.
This study presents an integrated computational framework that combines three‐dimensional quantitative structure–activity relationship (3D‐QSAR) modeling with molecular dynamics (MD) simulations to advance the rational design of triazole‐based urease inhibitors.
Neda Shakour, Aida Fayyaz, Farzin Hadizadeh, Saghi Sepehri, Baisakhi Banerjee   +4 more
wiley   +1 more source

Disruption of Mitochondrial Dynamics and Integrity Drives Divergent Metabolic Flexibility and Resilience in Podocytes

The FASEB Journal, Volume 39, Issue 24, 31 December 2025.
We investigated two models of mitochondrial dysfunction in podocytes, using two cell culture models: podocytes isolated from mice with Oma1 deletion (Oma1del) and mouse podocytes modified with an inducible knockdown of PHB2 (Phb2kd). OMA1 deficiency induced a glycolytic shift, enhanced glutamine anaplerosis, and sustained energy homeostasis after ...
Cem Özel, Katrin M. Reitmeier, Emilia Kieckhöfer, Khawla Abualia, Duc Nguyen‐Minh, Mahsa Matin, Henning Hagmann, Richard J. M. Coward, Sebastian Brähler, Philipp Antczak, Bernhard Schermer, Thomas Benzing, Patrick Giavalisco, Paul T. Brinkkoetter   +13 more
wiley   +1 more source