Results 121 to 130 of about 45,786 (250)
Summary Photorespiration is a mandatory metabolic repair shunt of carbon fixation by the Calvin–Benson cycle in oxygenic phototrophs. Its extent depends mainly on the CO2 : O2 ratio in chloroplasts, which is regulated via stomatal movements. Despite a comprehensive understanding of the role of photorespiration in mesophyll cells, its role in guard ...
Hu Sun+4 more
wiley +1 more source
The study focused on a mouse model of depression induced by lipopolysaccharides (LPS) and employed innovative multi‐omics approaches, including two‐dimensional gel electrophoresis (2‐DE) for proteomics, liquid chromatography–mass spectrometry (LC–MS) for metabolomics, and real‐time polymerase chain reaction (PCR) microarray technology to analyze the ...
Wen‐Wen Li+10 more
wiley +1 more source
Background To identify the pattern of protein expression in the retina from a patient with Leber's Congenital Amaurosis (LCA) secondary to a mutation in the AIPL1 gene. The retina from one eye of a patient with LCA and 7 control eyes were studied.
Honoré Bent+4 more
doaj +1 more source
Abstract Studies of cold‐active enzymes may elucidate the basis for low‐temperature activity and contribute to their wider application in energy‐efficient processes. Here we investigate the cold‐active GH2 β‐galactosidase from the psychrophilic bacterium Alkalilactibacillus ikkensis (AiLac).
Jan S. Nowak+9 more
wiley +1 more source
A contribution to breast cancer cell proteomics: detection of new sequences [PDF]
Ductal infiltrating carcinoma (DIC) of the breast is the most common and potentially aggressive form of cancer. Knowledge of proteomic profiles, attained both in vivo and in vitro, is fundamental to acquire as much information as possible on the proteins
Basiric\uf2, L.+5 more
core +1 more source
Kinetic parameters are reported for the reactions of whole substrates (kcat/Km, M–1 s–1) (R)-glyceraldehyde 3-phosphate (GAP) and dihydroxyacetone phosphate (DHAP) and for the substrate pieces [(kcat/Km)E·HPi/Kd, M–2 s–1] glycolaldehyde (GA) and ...
J. Richard+8 more
semanticscholar +1 more source
Impact of limited solvent capacity on metabolic rate, enzyme activities, and metabolite concentrations of S. cerevisiae glycolysis [PDF]
The cell's cytoplasm is crowded by its various molecular components, resulting in a limited solvent capacity for the allocation of new proteins, thus constraining various cellular processes such as metabolism.
Barabási, AL+3 more
core +1 more source
Statistical analysis to stabilize proteins [PDF]
Consensus design uses statistical information to introduce stabilizing mutations by replacing a wild-type residue with the most common amino acid in a multiple sequence alignment.
Nguyen, Tran
core
Role of Proteome Physical Chemistry in Cell Behavior. [PDF]
We review how major cell behaviors, such as bacterial growth laws, are derived from the physical chemistry of the cell's proteins. On one hand, cell actions depend on the individual biological functionalities of their many genes and proteins.
de Graff, Adam MR+3 more
core +3 more sources
Transitions between enzyme functional states are often connected to conformational changes involving electron or proton transport and directional movements of a group of atoms.
Davor Juretić+2 more
doaj +1 more source