Comparative Transcriptome Analysis of Litopenaeus vannamei Reveals That Triosephosphate Isomerase-Like Genes Play an Important Role During Decapod Iridescent Virus 1 Infection [PDF]
Frontiers in Immunology, 2020 Decapod iridescent virus 1 (DIV1) results in severe economic losses in shrimp aquaculture. However, little is known about the physiological effect of DIV1 infection on the host. In this study, we found that the lethal dose 50 of DIV1-infected Litopenaeus
Xuzheng Liao +10 more
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Methylglyoxal-Induced Modifications in Human Triosephosphate Isomerase: Structural and Functional Repercussions of Specific Mutations [PDF]
MoleculesTriosephosphate isomerase (TPI) dysfunction is a critical factor in diverse pathological conditions. Deficiencies in TPI lead to the accumulation of toxic methylglyoxal (MGO), which induces non-enzymatic post-translational modifications, thus ...
Ignacio de la Mora-de la Mora +6 more
doaj +2 more sources
Structural Analysis of an Epitope Candidate of Triosephosphate Isomerase in Opisthorchis viverrini [PDF]
Scientific Reports, 2018 Opisthorchis viverrini, a parasitic trematode, was recategorized as a group 1 biological carcinogen because it causes opisthorchiasis, which may result in cholangiocarcinoma. A new strategy for controlling opisthorchiasis is needed because of issues such
Jonghyeon Son +5 more
doaj +2 more sources
Disulfiram as a novel inactivator of Giardia lamblia triosephosphate isomerase with antigiardial potential [PDF]
International Journal for Parasitology: Drugs and Drug Resistance, 2017 Giardiasis, the infestation of the intestinal tract by Giardia lamblia, is one of the most prevalent parasitosis worldwide. Even though effective therapies exist for it, the problems associated with its use indicate that new therapeutic options are ...
Adriana Castillo-Villanueva +7 more
doaj +2 more sources
Glycolysis- and immune-related novel prognostic biomarkers of Ewing's sarcoma: glucuronic acid epimerase and triosephosphate isomerase 1. [PDF]
Aging (Albany NY), 2021 Jiang J +12 more
europepmc +3 more sources
First characterization of a microsporidial triosephosphate isomerase and the biochemical mechanisms of its inactivation to propose a new druggable target. [PDF]
Sci Rep, 2018 García-Torres I +8 more
europepmc +3 more sources
Triosephosphate isomerase from Fasciola hepatica: high-resolution crystal structure as a drug target. [PDF]
Acta Crystallogr F Struct Biol CommunKontellas G +5 more
europepmc +2 more sources
Differential Proteomic Analysis of Human Saliva using Tandem Mass Tags Quantification for Gastric Cancer Detection. [PDF]
, 2016 Novel biomarkers and non-invasive diagnostic methods are urgently needed for the screening of gastric cancer to reduce its high mortality. We employed quantitative proteomics approach to develop discriminatory biomarker signatures from human saliva for ...
Cao, Cheng-Xi +9 more
core +15 more sources
Phenylpyrrole fungicides act on triosephosphate isomerase to induce methylglyoxal stress and alter hybrid histidine kinase activity. [PDF]
Sci Rep, 2019 Brandhorst TT +4 more
europepmc +3 more sources
The Mechanism of the Triosephosphate Isomerase Reaction
Journal of Biological Chemistry, 1959 Sidney V. Rieder, Irwin A. Rose
openalex +3 more sources