Results 81 to 90 of about 45,786 (250)

Serum Biomarkers in Atlantic Salmon for Differential Diagnosis of Cardiomyopathy Syndrome and Pancreas Disease: Proteomic Identification of Serum Fibrinogen to Enhance Troponin Immunoassay as Optimal Diagnostic Approach

Journal of Fish Diseases, EarlyView.
ABSTRACT Cardiac viral diseases are among the major causes of economic losses in Atlantic salmon (Salmo salar L.) aquaculture. These include cardiomyopathy syndrome (CMS) caused by piscine myocarditis virus (PMCV) and pancreas disease (PD) caused by Atlantic salmonid alphavirus (SAV).
Francesca Riva, Lauren Elaine Black, Kim D. Thompson, Philippe Sourd, Andrei Bordeianu, Christopher C. Chadwick, Hooman Moghadam, Jorge Del‐Pozo, Janina Costa, Richard Burchmore, Nicola Brady, Lewis Moore, Suzanne McGill, Mark McLaughlin, Peter David Eckersall   +14 more
wiley   +1 more source

Investigation on the Metabolic Regulation of pgi gene knockout Escherichia coli by Enzyme Activities and Intracellular Metabolite Concentrations [PDF]

, 2006
An integrated analysis of the cell growth characteristics, enzyme activities, intracellular metabolite concentrations was made to investigate the metabolic regulation of pgi gene knockout Escherichia coli based on batch culture and continuous culture ...
Hassan, M. A., Nor ‘Aini, A. R., Shimizu, K., Shirai, Y.   +3 more
core   +1 more source

Coupling between Catalytic Loop Motions and Enzyme Global Dynamics [PDF]

, 2012
Catalytic loop motions facilitate substrate recognition and binding in many enzymes. While these motions appear to be highly flexible, their functional significance suggests that structure-encoded preferences may play a role in selecting particular ...
Ahmet Bakan, Dennis R. Livesay, Duygu Kocaman, Ivet Bahar, Pemra Doruker, Zeynep Kurkcuoglu   +5 more
core   +4 more sources

Triosephosphate Isomerase Gene Characterization and Potential Zoonotic Transmission of Giardia duodenalis

Emerging Infectious Diseases, 2003
To address the source of infection in humans and public health importance of Giardia duodenalis parasites from animals, nucleotide sequences of the triosephosphate isomerase (TPI) gene were generated for 37 human isolates, 15 dog isolates, 8 muskrat ...
Irshad M. Sulaiman, Ronald Fayer, Caryn Bern, Robert H. Gilman, James M. Trout, Peter M. Schantz, Pradeep Das, Altaf A. Lal, Lihua Xiao   +8 more
doaj   +1 more source

Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression

Molecular Oncology, Volume 19, Issue 8, Page 2233-2248, August 2025.
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park, Jae Won Oh, Hyewon Chung, Jung Won Kwon, Yi Rang Na, Kwang Pyo Kim, Seung Hyeok Seok   +6 more
wiley   +1 more source

Molecular epidemiology of Giardia duodenalis infection in humans in Southern Ethiopia: a triosephosphate isomerase gene-targeted analysis

Infectious Diseases of Poverty, 2018
BackgroundGiardia duodenalis is a species complex consisting of multiple genetically distinct assemblages. The species imposes a major public health crisis on developing countries.
Mengistu Damitie, Z. Mekonnen, Tadesse Getahun, D. Santiago, L. Leyns   +4 more
semanticscholar   +1 more source

An INS‐1 832/13 𝛽‐Cell Proteome Highlights the Rapid Regulation of Fatty Acid Biosynthesis in Glucose‐Stimulated Insulin Secretion

PROTEOMICS, Volume 25, Issue 15, Page 13-26, August 2025.
ABSTRACT Pancreatic beta cells secrete insulin in response to rising glucose levels, a process known as glucose‐stimulated insulin secretion (GSIS). Here, we acquire proteomes of rat pancreatic INS‐1 832/13 beta cells that were short‐term stimulated with 11 different glucose concentrations from 0 to 20 mM, quantifying the response of 3703 proteins ...
Nina Stremmel, Oliver Lemke, Kathrin Textoris‐Taube, Daniela Ludwig, Michael Mülleder, Julia Muenzner, Markus Ralser   +6 more
wiley   +1 more source

Tetrameric triosephosphate isomerase from hyperthermophilic Archaea [PDF]

FEBS Letters, 1996
Triosephosphate isomerase (TIM) of the hyperthermophilic Archaea Pyrococcus woesei and Methanothermus fervidus have been purified to homogeneity. The enzymes from the two hyperthermophiles represent homo‐tetramers of 100 kDa, contrary to all known bacterial and eukaryotic TIMs, which are dimers of 48–60 kDa. Molecular size determination of the TIM from
Reinhard Hensel, Michael Kohlhoff, Anke Dahm   +2 more
openaire   +3 more sources

Genetic adaptation despite high gene flow in a range‐expanding population

Molecular Ecology, Volume 34, Issue 15, August 2025.
Abstract Signals of natural selection can be quickly eroded in high gene flow systems, curtailing efforts to understand how and when genetic adaptation occurs in the ocean. This long‐standing, unresolved topic in ecology and evolution has renewed importance because changing environmental conditions are driving range expansions that may necessitate ...
Andy Lee, Benjamin N. Daniels, William Hemstrom, Cataixa López, Yuki Kagaya, Daisuke Kihara, Jean M. Davidson, Robert J. Toonen, Crow White, Mark R. Christie   +9 more
wiley   +1 more source

Principal basis for enzyme power [PDF]

, 2008
The reaction rate enhancement that enzymes produce had not been fully appreciated. The object of the article is to present the mechanism of the enormous catalytic power of the enzymes.
Alexander G. Foigel
core   +1 more source