Results 111 to 120 of about 10,090 (236)

AI‐Physics‐Experiment Trinity for Integrated Protein Dynamics Modeling

Advanced Science, EarlyView.
This review unites experiments, physics‐based simulations, and AI as a synergistic triad for protein dynamics modeling. It highlights integrative strategies, resolves sampling and forcefield bottlenecks, and outlines challenges and future directions for accurate, interpretable conformational ensemble prediction.
Chen Shi, Minying Low, Peng Xiu, Kresten Lindorff‐Larsen, Yong Wang   +4 more
wiley   +1 more source

Semi-supervised medical image captioning via anatomical collaborative evidence network. [PDF]

Front Med (Lausanne)
Zhou S, Liu Q, Cai L, Lu K, Qiao L, Xu N, Wu Y, Xu Y, Li J.   +8 more
europepmc   +1 more source

Pharmacological Inhibition of FKBP51 Mitigates Early Life Adversity‐Induced Social Deficits in Male Mice

Advanced Science, EarlyView.
Early life adversity triggers persistent social subordination and brain‐wide molecular dysregulation. Pharmacological inhibition of the stress‐mediator FKBP51 during the adversity period prevents these long‐term deficits and restores normative social hierarchy.
Joeri Bordes, Xiuqi Ji, Serena Gasperoni, Choham Sudre‐Chinsky, Amirali Kalbasi, Daniela Harbich, Cornelia Flachskamm, Paula Fontanet, Sowmya Narayan, Manfred Uhr, Christian Namendorf, Camilla Bellone, Alon Chen, Felix Hausch, Juan Pablo Lopez, Mathias V. Schmidt   +15 more
wiley   +1 more source

Deep learning-enabled scaffolding of spatial arrays of PfCSP epitopes. [PDF]

Proc Natl Acad Sci U S A
Wu NR, Castro KM, Beutler N, Lee WH, Raghavan SSR, Martin GM, Jain M, Agrawal S, Liguori A, Kalyuzhniy O, Skog PD, Terada S, Lai YC, Ndihokubwayo J, Lu D, Eskandarzadeh S, Alavi N, Phelps N, Tingle R, Youhanna JE, Amirzehni S, Rogers TF, Burton DR, Wilson IA, Ward AB, Correia BE, Schief WR.   +26 more
europepmc   +1 more source

Biodegradable Zn‐Based Implants: Progress, Challenges, and Pathways toward Clinical Translation

Advanced Science, EarlyView.
Exploring biodegradable Zn‐based implants offers a promising pathway to next‐generation biomedical devices with balanced degradation and biocompatibility. A comprehensive overview of biodegradable Zn‐based implants, covering their biological significance, material design principles, and advanced engineering strategies is provided.
Panfeng Zhao, Zhengquan Wang, Hui Yang, Xiyuan Zhang, Hanyuan Liu, Xiaotong Lu, Xiaocheng Li, Yanyan Liu, Xi Zhao, Wenhao Zhou, Yufeng Zheng   +10 more
wiley   +1 more source

Navigating Ternary Doping in Li-ion Cathodes With Closed-Loop Multi-Objective Bayesian Optimization. [PDF]

Adv Mater
Zeinali Galabi N, Liu CH, Jain M, Kamel M, Jia S, Bengio Y, McCalla E.   +6 more
europepmc   +1 more source

Uncertainty‐Aware Deep Ensembles for Robust and Reliable Chemical Sensor Arrays

Advanced Science, EarlyView.
A reliability‐aware electronic nose is developed using photothermally anchored metal‐catalyst decorated metal oxide nanofiber sensor arrays combined with deep ensemble learning. Diverse catalytic nanofiber channels generate gas‐specific response patterns, enabling selective identification and quantification of sulfur‐containing gases.
Sungwoo Eo, Ji‐Hwan Eum, Suk‐Jeong Kwon, Minji Sagong, Dongchan Kim, Dong‐Ha Kim   +5 more
wiley   +1 more source

Exosomal MicroRNAs as Drivers of Desmoplasia and Treatment Resistance in Breast Cancer: Mechanisms, Biomarker Potential, and Therapeutic Opportunities. [PDF]

Biomolecules
Chung J, Soung YH.
europepmc   +1 more source

Synergistic Effect of Gradient Conductivity and Gradient Microstructures Enabled Ultrasensitive and Ultrabroad Linear Flexible Tactile Sensors

Advanced Science, EarlyView.
A design of double gradient effect is proposed to resolve the contradictory optimization on sensitivity and linearity of piezoresistive tactile sensors. The ultrawide linearity is realized by the sequential trigger of pressure‐induced gradient conductivity‐enabled linear current owing to the gradient microstructures.
Yao Fang, Yiwei Wang, Bing Zheng, Liu Yang, Jingyi Yue, Qian Zhou, Jinrong Huang, Yongyun Mao, Qian Li, Jifei Wang, Dongsheng Tang, Yuxin Tang, Bingpu Zhou, Bing Ji   +13 more
wiley   +1 more source

Multiobjective Design of Growth Media with Genome-Scale Metabolic Models and Bayesian Optimization. [PDF]

Comput Struct Biotechnol J
Hallmann N, Guerra-Cornejo C, Burgess K, Merzbacher C, Oyarzún DA.   +4 more
europepmc   +1 more source