Results 131 to 140 of about 192,885 (309)

Effects of circular RNA hsa_circ_0058514 on the development and progression of triple-negative breast cancer

Zhongguo aizheng zazhi, 2019
Background and purpose: Circular RNA (circRNA) is a class of non-coding RNAs with important regulatory potential. It is involved in the development and progression of various cancers, but has not been reported in triple-negative breast cancer. The aim of
杨　睿, 陈俊霞
doaj  

Progress of Traditional Chinese Medicine in Regulating Immune Cell in the Tumor Microenvironment of Triple-Negative Breast Cancer

Integrative Cancer Therapies
Limitations in the therapies of triple-negative breast cancer, the strongest invasive subtype of breast cancer, have led to unsatisfactory clinical outcomes for patients.
Tao He MS, Silin Yu, Chaoyan Wu MD, PhD
doaj   +1 more source

Targeting Post‐Irradiation Thyroid Dysfunction: Electrospun Scaffolds As A Dual‐Action Approach for Antioxidant and Immune Modulation

Advanced Healthcare Materials, EarlyView.
Radiation‐induced hypothyroidism follows head and neck radiotherapy due to oxidative stress and inflammation. Electrospun polycaprolactone scaffolds containing adenosine have potential to modulate thyroid repair. Scaffolds enhance thyrocyte proliferation, antioxidant enzymes glutathione peroxidase and catalase, reduce senescence and apoptosis markers ...
Maria Heim, Ella‐Louise Handley, Daniel Grant, Lizi M. Hegarty, Elaine Emmerson, Anthony Callanan   +5 more
wiley   +1 more source

Immunotherapy in Triple-Negative Breast Cancer

Oncology and Therapy
Currently, immunotherapy has led to a paradigmatic shift in the treatment of many cancer types, including triple-negative breast cancer. Immunotherapy increases the efficacy of the immune system in treating cancer, with a durable effect due to immunologic memory.
Tiberi, Elisa, Parisi, Alessandro, Pistelli, Mirco, Savini, Agnese, Galassi, Federica, Reschini, Chiara, Quintavalle, Debora, Napoleoni, Riccardo, Ferrari, Carlo, Berardi, Rossana   +9 more
openaire   +2 more sources

Multi-omics Approaches to Study Triple-Negative Breast Cancer Metastasis

Triple-negative breast cancer (TNBC) is a highly aggressive subtype of breast cancer that lacks the expression of estrogen receptor, progesterone receptor, and human epidermal growth factor receptor 2.
Kaur, Jaspreet
core   +1 more source

Multidimensional Cellular Micro‐Compartments to Model Invasive Lobular Carcinoma Dormancy

Advanced Healthcare Materials, EarlyView.
Invasive lobular carcinoma (ILC) is an understudied subtype of breast cancer that is susceptible to late recurrences. In this study, micro‐compartmentalization techniques spanning multiple dimensions, including 2D, pseudo‐3D, and 3D, are integrated to uncover the mechanisms underlying ILC dormancy, revealing the central role of p27Kip1.
Xilal Y. Rima, Sarmila Majumder, Divya S. Patel, Chunyu Hu, Hong Li, Xin Huang, Kim Truc Nguyen, Jacob Doon‐Ralls, Chiranth K. Nagaraj, Mangesh D. Hade, Setty M. Magaña, Eswar Shankar, Xiaoli Zhang, Daniel G. Stover, Bhuvaneswari Ramaswamy, Eduardo Reátegui   +15 more
wiley   +1 more source

Tumor LDH-A expression and serum LDH status are two metabolic predictors for triple negative breast cancer brain metastasis

Scientific Reports, 2017
There are limited therapeutic methods for triple negative breast cancer in the clinic, which is easy to progress into the brain to form metastatic lesions and evolve into the terminal stage.
Tieying Dong, Zhaoliang Liu, Qijia Xuan, Zhuozhong Wang, Wenjie Ma, Qingyuan Zhang   +5 more
doaj   +1 more source

Triple-negative (ER, PgR, HER-2/neu) breast cancer in Indian women

, 2011
Vinayak W Patil1, Rajeev Singhai1, Amit V Patil2, Prakash D Gurav21Department of Biochemistry, Grant Medical College and Sir JJ Group of Hospitals, Mumbai, India; 2Department of Surgery, Government Medical College, Miraj, IndiaAbstract: The aim of our ...
Rajeev Singhai, et al, Amit V Patil, Vinayak W Patil   +3 more
core  

Matrix Stiffness Directs Stemness Signatures in Breast Cancer

Advanced Healthcare Materials, EarlyView.
We built lab‐grown breast cancer models to study how the stiffness of the tumor's surroundings influences cancer behavior. Softer environments encouraged more stem‐like, drug‐resistant cells, while stiffer ones kept cells more differentiated. These findings show that tissue mechanics drive cancer diversity and drug resistance, offering new insights for
Chantal Kopecky, Elvis Pandzic, Sean Porazinski, J Justin Gooding, Kristopher A Kilian   +4 more
wiley   +1 more source

Polycomb proteins and breast cancer

, 2013
In the Western world, breast cancer is the most frequent malignancy in women and still the leading cause of cancer related deaths, therefore, a better understanding of the disease is needed.
Fedele, Vita
core