Results 141 to 150 of about 192,885 (309)

Thermally Modulated Metasurface Sensor for Dynamic and Time‐Resolved Isolation of Extracellular Vesicles

open access: yesAdvanced Materials, EarlyView.
A thermally adaptive plasmonic metasurface, functionalized with poly(N‐isopropylacrylamide) (PNIPAM) and anti‐CD63 antibodies, enables precise, on‐demand capture and release of extracellular vesicles (EVs). Delivering high recovery, improved purity, and intact vesicle structure, the platform offers a versatile, label‐free solution for real‐time EV ...
Beyza Nur Kucuk   +7 more
wiley   +1 more source

Turning Unpredictable Biomolecule Adsorption to Controlled Corona Formation: Focus on Carbon Nanomaterials

open access: yesAdvanced Materials, EarlyView.
Controlling the protein corona formation onto carbon nanomaterials (CNMs) enhances their functionalities as platforms for cancer theranostics. Here, we reviewed the effects of the intrinsic and acquired properties of CNMs on protein corona formation, the consequent biological and toxicological outcomes, and the strategies to reshape corona formation ...
Yajuan Zou   +5 more
wiley   +1 more source

Selenium and Triple Negative Breast Cancer

open access: yesActa Medica Academica
Background. The deadliest, most dangerous subtype of breast cancer is triple-negative, which lacks treatment targets and accounts for 30% of all breast cancer-related deaths worldwide. TNBC is characterized by the expression of no estrogen, proges- terone, or human epidermal growth factor 2 receptors.
Sidira, Despoina   +5 more
openaire   +3 more sources

Distant metastasis in triple-negative breast cancer

open access: yes, 2014
Triple-negative breast cancer (TNBC) relapses more frequently than hormone receptor-positive subtypes and is often associated with poor outcomes. This retrospective study reviewed the pattern of distant metastasis with regard to survival in patients with
Tseng, L. M.;Hsu, N. C.;Chen, S. C.;Lu, Y. S.;Lin, C. H.;Chang, D. Y.;Li, H.;Lin, Y. C.;Chang, H. K.;Chao, T. C.;Ouyang, F.;Hou, M. F.   +1 more
core  

Super‐Resolution Ultrasound Based Cell Tracking With Polymeric Nanobubbles

open access: yesAdvanced Materials, EarlyView.
This study presents a super‐resolution ultrasound platform for tracking cells in vivo. Biocompatible polymeric nanobubbles are used as highly echogenic intracellular labels. Following the injection of cells and microbubbles, ultrasound localization microscopy (ULM) can dynamically match the microvascular architecture and individual cell trajectories ...
Junlin Chen   +19 more
wiley   +1 more source

Dual Target of EGFR and mTOR Suppresses Triple-Negative Breast Cancer Cell Growth by Regulating the Phosphorylation of mTOR Downstream Proteins

open access: yes, 2023
Jing Ma,1 Chao Dong,1 Yan-Zhen Cao,2 Bin-Lin Ma1 1Department of Breast and Thyroid Surgery, Affiliated Cancer Hospital of Xinjiang Medical University, Urumqi, 830000, People’s Republic of China; 2Pathology Center, Affiliated Cancer Hospital of Xinjiang ...
Ma J, Dong C, Cao YZ, Ma BL
core  

Cell Adhesion by Design: Engineering Tissue Culture Scaffolds With Adhesion Cues

open access: yesAdvanced Materials Interfaces, EarlyView.
ABSTRACT In scaffold‐based tissue engineering, the matrix should provide adequate adhesion cues for cell attachment, spreading, and function. Given the multitude of adhesion receptors and the diversity of scaffolds, there are many approaches to render scaffolds adhesive, even though they are not all equivalent.
Dalia Dranseike   +3 more
wiley   +1 more source

Advances in the treatment of triple-negative breast cancer with CDK4/6 inhibitors

open access: yesZhongguo aizheng zazhi, 2019
The regulatory mechanism of cell cycle plays an important role in the occurrence and development of tumors. In recent years, a number of studies have shown that cyclin-dependent kinase 4/6 (CDK4/6) inhibitors have good efficacy in patients with estrogen ...
ZHU Xiuzhi   +4 more
doaj  

Common breast cancer susceptibility alleles are associated with tumour subtypes in BRCA1 and BRCA2 mutation carriers: results from the Consortium of Investigators of Modifiers of BRCA1/2

open access: yes, 2011
The associations of the 12 SNPs with risk for BRCA1 and BRCA2 carriers differ by ER-positive or ER-negative breast cancer status. The apparent differences in SNP associations between BRCA1 and BRCA2 carriers, and non-carriers, may be explicable by ...
Donaldson, A.   +999 more
core   +1 more source

Modulus‐Switchable Miniature Robots for Biomedical Applications: A Review

open access: yesAdvanced Robotics Research, EarlyView.
Materials, robot designs, proof‐of‐concept functions, and biomedical applications of modulus‐switchable miniature robots. Miniature soft robots have shown great potential in biomedical applications due to their excellent controllability and suitable mechanical properties in biological environments.
Chunyun Wei, Yibin Wang, Jiangfan Yu
wiley   +1 more source

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