Results 221 to 230 of about 164,343 (265)

Nanoparticle‐Mediated TIPE1 mRNA Delivery Enhances Paclitaxel Sensitivity in Triple‐Negative Breast Cancer by Modulating RAB7A Ubiquitination‐Associated Stability and Autophagy

open access: yesAdvanced Science, EarlyView.
TIPE1m NPs nanoparticles restore TIPE1 expression, promote RAB7A ubiquitination and degradation, suppress autophagic flux, and resensitize paclitaxel‐resistant triple‐negative breast cancer to therapy. ABSTRACT Acquired paclitaxel (PTX) resistance remains a major obstacle in triple‐negative breast cancer (TNBC) treatment.
Wei Hu   +9 more
wiley   +1 more source

Polygenic Risk Scores for Breast Cancer Among African American Women With High Risk.

open access: yesJAMA Netw Open
Sun Y   +10 more
europepmc   +1 more source

Investigation of the synergic effect of mocetinostat and capecitabine in a triple-negative breast neoplasms mouse model

Journal of Investigative Medicine
Combined administration of two or more drugs is emerging as a new strategy in triple-negative breast neoplasms. This is the first study to investigate the combination of the histone deacetylase inhibitor mocetinostat and the antimetabolite drug capecitabine in triple-negative mammary neoplasms in a preclinical mouse model.
Onur Eroglu, Hacer Kaya Cakir
exaly   +5 more sources

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