Results 231 to 240 of about 171,342 (310)

Risk of CNS relapse following pathological complete response to neoadjuvant chemotherapy in early breast cancer. [PDF]

Breast Cancer Res Treat
de Moura Leite L, de Almeida GR, Tavares MC, Cesca MG, Campos FAB, de Oliveira FA, Dornellas DMS, Saldanha EF, Guimarães PT, de Arruda DDS, de Held MFSD, Viana RL, Moura FGR, Loose SK, Silva SF, Pirolli R, Fogassa CAZ, Mattos BRS, Sanches SM, de Lima VCC.   +19 more
europepmc   +1 more source

Tumor‐Induced Splenic Remodeling: Mechanisms of Systemic Immunosuppression and Emerging Therapeutic Opportunities

Advanced Science, EarlyView.
ABSTRACT Despite the transformative impact of cancer immunotherapies such as immune checkpoint blockade, durable clinical responses remain limited. Increasing evidence indicates that antitumor immunity is governed not only by the tumor microenvironment, but also by systemic immune regulation mediated by peripheral immune organs. Among these, the spleen
Yuehua Liu, Xiaoqian Nie, Xiaofei Gao
wiley   +1 more source

Association of T2-Weighted Imaging Features in Invasive Breast Cancer With Clinicopathologic Features and Neoadjuvant Treatment Outcomes. [PDF]

Korean J Radiol
Youn I, Roh YH, Kim MJ, Yoon JH, Kwon MR, Park VY.   +5 more
europepmc   +1 more source

Multimodal Multiorgan‐on‐a‐Chip Platform for Probing Liver‐Tumor Interactions and Advancing Prodrug Screening

Advanced Science, EarlyView.
This work introduces a multimodal multi‐OoC platform that overcomes current limitations in liver‐tumor interaction studies and prodrug screening. By integrating dynamic microfluidic circuits, electrochemical sensing, and mass analysis, this platform enables non‐invasive, longitudinal monitoring of drug metabolism and hepatotoxicity, offering a ...
Dan Wang, Yisong Huang, Weijian Zhao, Tian Chen, Siyu Bai, Denghui Guo, Mengying Wang, Yaoyao Zhao, Liang Zhao, Guangsheng Guo, Xiayan Wang   +10 more
wiley   +1 more source

Association between HbA1c and breast cancer risk in women with type 2 diabetes mellitus: A case-control study. [PDF]

Medicine (Baltimore)
Kandasamy G, Arumugam V, Orayj K, S Alanazi T, Asiri R, Alshahrani AM, Hmlan A, Sulaiman A Abumelha M, Turki IAM, Rani VI, Prakash GG, Mani V, Abu-Elfotuh K, Prabahar K.   +13 more
europepmc   +1 more source

PRMT5/Sohlh2/Sirt1 Signaling Pathway in Vascular Endothelial Cells Modulates Lung Metastasis of Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
The cover image shows that vascular endothelial cells play an important role in lung metastasis of TNBC. Endothelial Sohlh2 acts as a gatekeeper against TNBC lung metastasis by limiting endothelial activation and tumor cell passage. PRMT5 reduces Sohlh2 stability, weakening this protective barrier.
Ruihong Zhang, Fengqin Wang, Lanlan Liu, Qi Zhang, Xiaoning Huo, Yanhui Nan, Yanli Dong, Yunling Xiao, Jing Hao   +8 more
wiley   +1 more source

Adjuvant Chemotherapy Outcomes in Older Adults With Nonmetastatic Triple-Negative Breast Cancer.

JAMA Netw Open
Anampa JD, Avila J, Brodsky M, Hakim E, Obeng-Gyasi S, Alvarez A, Bernabe-Ramirez C, Xue X.   +7 more
europepmc   +1 more source

Magnetic resonance imaging as a non-invasive breast cancer tool - the relevance of breast edema score: A retrospective study. [PDF]

World J Radiol
Vasilska A, Tsvetkova S, Doykova K, Chervenkov L, Velikova T, Vasilska M, Sariyan S.   +6 more
europepmc   +1 more source

Enhanced Intracellular Stability and Translation Efficiency of mRNA Drugs by a 2‐arm mRNA Platform

Advanced Science, EarlyView.
We constructed a 2‐arm mRNA, characterized by a unique topology formed through the dimerization of two mRNA 3’ tails. The 2‐arm mRNA improves 3’ tail stability and resistance to nuclease degradation, resulting in an intracellular half‐life of up to 65 h. This method substantially enhances the translation capacity of mRNA drugs.
Xucong Teng, Jiahao Lin, Qiushuang Zhang, Xiangdong Zhang, Yicong Dai, Jinghong Li   +5 more
wiley   +1 more source

Publication proportions for registered breast cancer trials: before and following the introduction of the ClinicalTrials.gov results database [PDF]

core   +1 more source