Results 61 to 70 of about 58,367 (308)

Triple Helix, Fall 2019 [PDF]

open access: yes, 2019
Table of Contents: From the Expert / by Nathaniel Woodward (p. 2) -- Lab-Cultured Meat / by Victor Liaw (p. 4) -- Tooth Regenerative Therapy / by Omkar Patel (p. 6) -- Voluntourism / by Sofia Ferguson (p.
Thomas, Emmilyne   +11 more
core   +1 more source

The design of a crown ether receptor for selective collagen binding

open access: yesAdvanced Industrial and Engineering Polymer Research, 2022
Collagen, crucial insoluble fibrous protein in connective tissue and extracellular matrix, plays an important role in the body structures of animals. It is most distinct for its triple helix structure.
Yihuan He
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Knowledge exchange and the third mission of universities : Introduction: the triple helix and the third mission – Schumpeter revisited

open access: yes, 2010
Joseph Schumpeter (1883–1950) is well known as an economist, among other things, for his seminal contribution explaining long-term economic growth in terms of innovation and technological progress. He identified innovation at the heart of upswings in the
Girma Zawdie, Zawdie, Girma
core   +1 more source

Design Rules for ‘Triple Helix’ Organizations

open access: yesTechnology Innovation Management Review, 2019
The image of the triple helix with three forces spiraling around each other has proven to be a powerful and inspiring image of the collaboration between government, business, and academia. The partners in such collaborative arrangements no doubt share an
Ben Dankbaar
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Triple Helix, September 21, 2007 [PDF]

open access: yes, 2007
This is the concert program of the Triple Helix performance on Friday, September 21, 2007 at 12:00 p.m., at the Concert Hall, 855 Commonwealth Avenue. Works performed were Trio on Irish Folk Tunes by Frank Martin and Trio by Maurice Ravel.
School of Music, Boston University
core  

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

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