Evaluation of carbonic anhydrase IX as a therapeutic target for inhibition of breast cancer invasion and metastasis using a series of in vitro breast cancer models [PDF]
, 2015 This research was financed in part by a Grant of the 7th Framework Program of the European Union (METOXIA project; HEALTH‐F2‐2009‐222741) and the NGI Pre- Seed grant (NWO n° 93613002).Triple negative, resistant or metastatic disease are major factors in ...
Kunkler, Ian H. +30 more
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Phospho-Akt expression is high in a subset of triple negative breast cancer patients [PDF]
, 2014 The most commonly used biomarkers to predict the response of breast cancer patients to therapy are oestrogen receptor (ER), progesterone receptor (PgR), and human epidermal growth factor receptor 2 (HER2).
Baldacchino, Shawn +6 more
core +1 more source
World Journal of Surgical Oncology, 2020 Background Metaplastic breast cancer remains poorly characterized given its rarity and heterogeneity. The majority of metaplastic breast cancers demonstrate a phenotype of triple-negative breast cancer; however, differences in clinical outcomes between ...
Evan Morgan +18 more
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miR-331-3p Suppresses Cell Proliferation in TNBC Cells by Downregulating NRP2
Technology in Cancer Research & Treatment, 2020 Purpose: Triple-negative breast cancer is characterized by fast progression with high possible for metastasis and poor survival. Dysfunction of microRNAs plays an important role in the initiation and progression of cancer.
Mingchuan Zhao PhD +5 more
doaj +1 more source
Technology in Cancer Research & Treatment, 2020 Background: Triple-negative breast cancer encompasses heterogeneous subtypes. Neoadjuvant chemotherapy is ineffective against some triple-negative breast cancers, while others show a favorable prognosis despite chemoresistance.
Koichi Kubouchi MD +3 more
doaj +1 more source
Breast cancer receptor status assessment and clinicopathological association in Nigerian women: A retrospective analysis [PDF]
, 2014 Background: Breast cancer markers are becoming increasingly important in breast cancer research due to their impact on prognosis, treatment and survival.
Ayodele, Sanni D. +5 more
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MicroRNAs expression in triple negative vs non triple negative breast cancer in Tunisia: interaction with clinical outcome. [PDF]
PLoS ONE, 2014 MicroRNAs are small, non coding regulatory molecules containing approximately 21 to 25 nucleotides. They function as controllers of expression at post transcriptional levels of most human protein-coding genes and play an essential role in cell signaling ...
Imen Medimegh +10 more
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Homogeneous datasets of triple negative breast cancers enable the identification of novel prognostic and predictive signatures [PDF]
, 2011 Background: Current prognostic gene signatures for breast cancer mainly reflect proliferation status and have limited value in triple-negative (TNBC) cancers.
Pusztai, Lajos +44 more
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Treatment of thrice-negative breast cancer in a patient with metabolic syndrome
Исследования и практика в медицине, 2021 Breast cancer (BC) remains one of the most common diseases of the female population. According to statistics, breast cancer is detected in every eighth woman. Approximately 20‑24% of breast cancer patients are diagnosed with triple negative breast cancer.
G. E. Roitberg +2 more
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Research progress of single-cell sequencing in neoadjuvant chemotherapy for triple-negative breast cancer [PDF]
Zhongguo aizheng zazhi, 2021 Triple-negative breast cancer is the most invasive and malignant type of breast cancer. At present, therapy for triple-negative breast cancer is the comprehensive treatment regimens based on chemotherapy, in which neoadjuvant chemotherapy plays an ...
HU Xi’e , YANG Zhenyu , XUE Jingyi , YANG Ping , PENG Shujia , YUAN Lijuan , BAO Guoqiang
doaj +1 more source