Results 101 to 110 of about 9,480,720 (296)
Molecular and Electronic Structures of Macrocyclic Compounds Formed at Template Synthesis in the M(II)-Thiocarbohydrazide-Diacetyl Triple Systems: A Quantum-Chemical Analysis by DFT Methods. [PDF]
Molecules, 2023 Mikhailov OV, Chachkov DV.
europepmc +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
THE TRIPLE SYSTEM ZETA AQUARII* [PDF]
The Astrophysical Journal, 2016 ABSTRACT Zeta Aquarii is a bright and nearby (28 pc) triple star with a 26-year astrometric subsystem. Almost one-half of the outer 540-year visual orbit has been covered in 238 years of its observations. Both inner and outer orbits are revised here taking into account recent direct resolution of the inner pair Aa,Ab. The inner orbit has
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Approximate Homomorphisms and Derivations on Normed Lie Triple Systems
Journal of Function Spaces, 2014 We investigate the generalized Hyers-Ulam stability of homomorphisms and derivations on normed Lie triple systems for the following generalized Cauchy-Jensen additive equation r0f((s∑j=1pxj+t∑j=1dyj)/r0)=s∑j=1pf(xj)+t∑j=1df(yj), where r0,s, and t are ...
Hark-Mahn Kim, Juri Lee
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Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Embeddings of Steiner triple systems
Discrete Mathematics, 1973 info:eu-repo/semantics ...
Doyen, Jean, Wilson, Richard R.M.
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Measuring the Knowledge Base of Regional Innovation Systems in Germany in terms of a Triple Helix Dynamics [PDF]
While a market economy seeks equilibrium, a knowledge-based economy may upset this tendency towards stabilization by adding the feedback of globalization.
Leydesdorff, Loet, Fritsch, Michael
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Triple flame structure and diffusion flame stabilization [PDF]
, 1994 The stabilization of diffusion ñames is studied using asymptotic techniques and numerical tools. The configuration studied corresponda to parallel streams of cold oxidizer and fuel initially separated by a splitter píate.
Poinsot, T. +5 more
core
Triple Fused Supernumerary Kidneys with Five Pelvicalyceal Systems
Société Internationale d’Urologie JournalWe present a case of supernumerary kidney with fusion of all three kidney units with five pelvicalyceal system (bilateral bifid PCS and PCS of supernumerary kidney). This is probably the first such case reported in literature.
Naveen Kumar +2 more
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