Results 81 to 90 of about 228,875 (264)

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Some Problems and Conjectures About Voloshin Triple Systems

open access: yesMathematics
In this paper we give a short survey of Voloshin Triple Systems, which are Steiner Triple Systems with a vertex colouring which colour the blocks using exactly two colours.
Mario Gionfriddo
doaj   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

Identifying Hierarchically Triple Star Systems with Gaia DR3 and LAMOST

open access: yesThe Astronomical Journal
Triple star systems are critical for understanding stellar dynamics and compact objects in astrophysics, yet confirmed hierarchical triples identified via spectroscopy remain limited.
Tongyu He   +10 more
doaj   +1 more source

Latin directed triple systems

open access: yesDiscrete Mathematics, 2012
A Steiner triple system, a \(STS\), (a Mendelsohn triple system, a \(MTS\), a directed triple system, a \(DTS\)) is a pair \((V,\mathcal{B})\) where \(B\) is a set of points and \(\mathcal{B}\) is a collection of triples (cyclically oriented triples, transitively oriented triples) of distinct points from \(V\) so that each pair (ordered pair) of points
Ales Drápal   +2 more
openaire   +2 more sources

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Configurations in triple systems: avoidance and decomposition

open access: yesLe Matematiche, 1992
See directly the article.
Alex Rosa
doaj  

Approximate Homomorphisms and Derivations on Normed Lie Triple Systems

open access: yesJournal of Function Spaces, 2014
We investigate the generalized Hyers-Ulam stability of homomorphisms and derivations on normed Lie triple systems for the following generalized Cauchy-Jensen additive equation r0f((s∑j=1pxj+t∑j=1dyj)/r0)=s∑j=1p‍f(xj)+t∑j=1d‍f(yj), where r0,s, and  t are ...
Hark-Mahn Kim, Juri Lee
doaj   +1 more source

Periodic Motion and Stability of Gravitational Planar Triple Systems

open access: yesFrontiers in Astronomy and Space Sciences, 2019
The stability of gravitational triple systems is a well-known problem in celestial mechanics. The basic model used is the general three body problem (GTBP).
George Voyatzis   +1 more
doaj   +1 more source

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