Results 61 to 70 of about 228,875 (264)
Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
Nonsequenceable Steiner triple systems [PDF]
Bull. ICA, 2019 A partial Steiner triple system is is $sequenceable$ if the points can be sequenced so that no proper segment can be partitioned into blocks. We show that, if $0 \leq a \leq (n-1)/3$, then there exists a nonsequenceable PSTS$(n)$ of size $\frac{1}{3}\binom{n}{2}-a$, for all $n \equiv 1 \pmod{6}$ except for $n=7$.
Donald L. Kreher, Douglas R. Stinson
openaire +2 more sources
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Fine-tuning of light-time effect in triple systems
Astronomy & AstrophysicsContext. The sequence of eclipses of binary stars is subject to inequalities for various reasons. The presence of a third component in the system causes periodic motion of the binary’s center of mass along the line of sight of an observer.
Vokrouhlický David
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
ПРЕДПОСЫЛКИ И УСЛОВИЯ ФОРМИРОВАНИЯ МОДЕЛИ«ТРОЙНОЙ СПИРАЛИ» ИННОВАЦИЙ В КАЗАХСТАНЕ
Экономика: стратегия и практика, 2018 The purpose of the paper is to consider the concept of the “triple helix of innovations”, to study the preconditions of it’s formation and to identify the conditions for the implementation of the “triple helix of innovations” model into the innovative ...
F. M. Dnishev, A. S. Gabdulina
doaj
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Triple stratified systems equilibrium diagrams classification
Тонкие химические технологии, 2011 Triple stratified systems equilibrium diagrams classification with account taken of different quantity of areas for both two- and three-phase stratification has been offered.
L. A. Serafimov +2 more
doaj
Mutual Orbit Alignment in Resolved Triple Systems
The Astrophysical JournalA sample of 278 triple systems with outer separations under 300 au and resolved inner pairs is studied, focusing on the mutual alignment between the inner and outer orbits.
Andrei Tokovinin
doaj +1 more source
SOIL WATER RETENTION CURVE AND S INDEX AS SOIL PHYSICAL QUALITY INDICATORS FOR INTEGRATED PRODUCTION SYSTEMS [PDF]
Engenharia Agrícola, 2018 Assess the physical quality of agricultural soils it is important to establish the management more adequate for plant growth. In this study, the soil water retention curve and S index as indicators of soil physical quality were evaluated in five ...
Wellington de A. Magalhães +4 more
doaj +1 more source