Results 51 to 60 of about 9,480,720 (296)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
The Astronomical JournalJoint analysis of position measurements and radial velocities of six triple stellar systems is conducted to determine their inner and/or outer orbits. Accumulation of such data is needed to study the architecture of stellar hierarchies and its relation ...
Andrei Tokovinin
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Discrete Mathematics, 1974 AbstractA t-design (λ, t, d, n) is a system B of sets of size d from an n-set S, such that each t subset of S is contained in exactly λ elements of B. A t-design is indecomposable (written IND(λ, t, d, n)) if there does not exist a subset B ⊆ B such that B is a (λ, t, d, n) for some λ, 1 ⩽ λ < λ. A triple system is a (λ; 2, 3, n).
openaire +2 more sources
Classifying two-dimensional hyporeductive triple algebra
International Journal of Mathematics and Mathematical Sciences, 2006 Two-dimensional real hyporeductive triple algebras (h.t.a.) are investigated. A classification of such algebras is presented. As a consequence, a classification of two-dimensional real Lie triple algebras (i.e., generalized Lie triple systems) and two ...
A. Nourou Issa
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
, 2020 Sverige har målsättningen att minska växthusgasutsläppen från inrikes transporter (exklusive flyg) med 70% till 2030 jämfört med 2010 samt att nå nettonollutsläpp av växthusgaser till atmosfären till 2045 (för hela ekonomin).
Vierth, Inge +3 more
core +1 more source
Knowledge exchange and the third mission of universities : Introduction: the triple helix and the third mission – Schumpeter revisited [PDF]
, 2010 Joseph Schumpeter (1883–1950) is well known as an economist, among other things, for his seminal contribution explaining long-term economic growth in terms of innovation and technological progress. He identified innovation at the heart of upswings in the
Zawdie, Girma
core +4 more sources
Triple P - Positive Parenting Program: Group Triple P [PDF]
, 2015 FlyerGroup Triple P is a great way to meet other parents facing the same issues as you. Each group has about 10 or 12 parents, so you won’t feel alone!
Barnardos, Triple P
core +2 more sources