Results 81 to 90 of about 6,814 (284)

Development of human monoclonal antibodies against TARM1 by yeast display

open access: yesFEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe   +5 more
wiley   +1 more source

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

open access: yesFEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel   +8 more
wiley   +1 more source

3D-printed ceramic triply periodic minimal surface structures for design of functionally graded bone implants

open access: yesMaterials & Design, 2020
Stress shielding is one of the main problems that lead to bone resorption and revision surgery after implantation. Most of the commercially available metallic non-porous bone implants have a much greater stiffness than the native human bones and are ...
Sanjairaj Vijayavenkataraman   +2 more
doaj   +1 more source

Effect of Pore Size of Porous-Structured Titanium Implants on Tendon Ingrowth

open access: yesApplied Bionics and Biomechanics, 2022
Purpose. The reconstruction of a tendon insertion on metal prostheses is a challenge in orthopedics. Of the available metal prostheses, porous metal prostheses have been shown to have better biocompatibility for tissue integration.
Yupeng Guo   +9 more
doaj   +1 more source

A Systematic Comparison of Alpha‐Synuclein Seed Amplification Assays for Increasing Reproducibility

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Seed amplification assays (SAAs) enable ultrasensitive detection of misfolded α‐synuclein across biofluids and tissues. Yet, heterogeneity in protocols limits cross‐study comparability and clinical translation. Here, we review α‐synuclein SAA methods and their performance across various biological matrices.
Manuela Amaral‐do‐Nascimento   +3 more
wiley   +1 more source

Ultra-stiff and quasi-elastic-isotropic triply periodic minimal surface structures designed by deep learning

open access: yesMaterials & Design
Multi-functional triply periodic minimal surface (TPMS) structures have been widely studied and proven to have significant importance. Most studies are based on several typical TPMSs. However, some research suggests that the hybrid forms of the TPMSs can
Ruiguang Chen   +8 more
doaj   +1 more source

On the Lightweight Potential of Laser Additive Manufactured NiTi Triply Periodic Minimal Sheet Lattices

open access: yesAdvanced Engineering Materials, EarlyView.
This study explores the lightweight potential of laser additive‐manufactured NiTi triply periodic minimal surface sheet lattices. It systematically investigates the effects of relative density and unit cell size on surface quality, deformation recovery, compression behavior, and energy absorption.
Haoming Mo   +3 more
wiley   +1 more source

Energy absorption of gradient triply periodic minimal surface structure manufactured by stereolithography

open access: yesReviews on Advanced Materials Science
Triply periodic minimal surface (TPMS) metamaterials possess exceptional properties not commonly found in natural materials. TPMS metamaterials are used in lightweight structures and impact energy absorption structures due to their surface geometry and ...
Liang Yingjing   +8 more
doaj   +1 more source

Smectic Phases with Cubic Symmetry: The Splay Analog of the Blue Phase

open access: yes, 2002
We report on a construction for smectic blue phases, which have quasi-long range smectic translational order as well as long range cubic or hexagonal order.
B. A. DiDonna   +6 more
core   +1 more source

Crystal-Inspired Cellular Metamaterials and Triply Periodic Minimal Surfaces

open access: yesBiomimetics
Triply periodic minimal surfaces (TPMSs) are found in many natural objects including butterfly wings, sea urchins, and biological membranes. They simultaneously have zero mean curvature at every point and a crystallographic group symmetry. A metamaterial can be created from such periodic surfaces or used as a reinforcement of a composite material ...
Maxim Arsentev   +8 more
openaire   +3 more sources

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