Results 61 to 70 of about 807 (197)

Spatiotemporal Targeting Randle Cycle and Immune Checkpoint for Potent Antitumor Therapy

Advanced Science, EarlyView.
A glucose oxidase‐based nanogel (GOX‐NG) system using catechol‐functionalized alginate, exhibits enhanced tumor penetration, prolonged retention, and sustained glucose depletion in the tumor microenvironment. When combined with a fatty acid oxidation inhibitor, it implements dual metabolic suppression, thereby enhancing ROS‐induced immunogenic cell ...
Yuan Gao, Zijian Gong, Yixuan Fu, Jianan Zheng, Xiao Sang, Binglin Chen, Qinzhi Su, Weiping Gao, Fei Duan, Jinqi Wei, Xuliang Deng, Xinyu Liu   +11 more
wiley   +1 more source

Efficient Adsorption‐Based Direct Air Capture Via Triply Periodic Minimal Surface Architectures

Advanced Science, EarlyView.
Architected triply periodic minimal surface (TPMS) contactors reshape direct air capture by replacing straight‐channel diffusion limits with convection‐enhanced CO2 transport. Chaotic advection thins boundary layers and exposes fast adsorption sites, enabling 70%–75% more fast sites, 114% higher productivity, and 51.8% lower energy consumption than ...
Qingyang Shao, Zhuozhen Gan, Chengcheng Long, Man Zhang, Yihe Miao, Yuehui Li, Xuancan Zhu   +6 more
wiley   +1 more source

Permeability and microstructural parameters of 3D‐printed triply periodic minimal surface (TPMS) hydroxyapatite scaffolds

Journal of the American Ceramic Society
Abstract The search for designing and fabricating truly tissue‐like scaffolds is one of the grand challenges in bone tissue engineering. The question on which parameters are actually the most representative of scaffold architecture and, thus, have to be more carefully designed and considered for assessing the scaffold suitability ...
Gabrieli R., Schiavi A., Pennecchi F. R., Alidoost D., Schwentenwein M., D'Andrea L., Vena P., Verne' E., Baino F.   +8 more
openaire   +2 more sources

YAP1‐Driven Pathogenic Fibro‐Adipogenic Progenitors Secrete IL‐6 and FGF21 to Mediate Muscle‐Bone Crosstalk and Promote Bone Loss

Advanced Science, EarlyView.
Fibro‐adipogenic progenitors (FAPs) in atrophic muscle undergo YAP1‐driven pathogenic activation, secreting IL‐6 and FGF21 as bone‐catabolic myokines that mediate muscle‐bone crosstalk and promote bone loss. Genetic or pharmacological targeting of this YAP1‐FAP‐myokine axis rescues skeletal deterioration, identifying FAP‐derived myokines as therapeutic
Xiaoyu Cai, Tao Xu, Rui Ma, Weikun Meng, Shutao Gao, Yakefu Abulizi, Alafate Kahaer, Chuanhui Xun, Maierdan Maimaiti, Rui Cao, Weidong Liang, Polati Maimaiti, Qiang Deng, Jun Sheng, Ting Wang, Mingchong Liu, Weibin Sheng   +16 more
wiley   +1 more source

TPMS-based metamaterials with tuneable elastic anisotropy and mechanical coupling

Materials & Design
Architectured metamaterials typically comprise of unit cells with cubic stiffness tensors and this cubic symmetry greatly restricts the available design space of mechanical properties than can be attained. In this paper, this conventional design approach
Stephen Daynes
doaj   +1 more source

Nanoparticle‐Mediated TIPE1 mRNA Delivery Enhances Paclitaxel Sensitivity in Triple‐Negative Breast Cancer by Modulating RAB7A Ubiquitination‐Associated Stability and Autophagy

Advanced Science, EarlyView.
TIPE1m NPs nanoparticles restore TIPE1 expression, promote RAB7A ubiquitination and degradation, suppress autophagic flux, and resensitize paclitaxel‐resistant triple‐negative breast cancer to therapy. ABSTRACT Acquired paclitaxel (PTX) resistance remains a major obstacle in triple‐negative breast cancer (TNBC) treatment.
Wei Hu, Qishuai Chen, Yan Ma, Yang Liu, Xianing Dong, Wenjuan Wei, Jianxin Du, Shusheng Qiu, Maojin Tian, Peiqing Zhao   +9 more
wiley   +1 more source

Experimental investigation of Triply Periodic Minimal Surfaces for high-temperature solar receivers

Case Studies in Thermal Engineering
This study experimentally investigates Triply Periodic Minimal Surfaces (TPMS) as structured porous media for concentrated solar power systems. Two mock-up planar solar receivers with different TPMS lattices, Diamond and SplitP, were fabricated using ...
A. Mortazavi, A.L. Ávila-Marín, H. Ebadi, E. Gajetti, C. Piatti, L. Marocco, L. Savoldi   +6 more
doaj   +1 more source

Investigation of torsional and fatigue resistance properties based on triply periodic minimal surfaces (TPMS)

Journal of Physics: Conference Series
Abstract Triply periodic minimal surfaces (TPMS) are algebraic surfaces found in nature, defined by implicit functions, and exhibit exceptional properties in various fields such as mechanics, computer graphics, and tissue engineering.
Jijun Jiang, Zhanlong Cao, Jing Wu, Hongwei Lu, Jiahao Zhang   +4 more
openaire   +1 more source

Bioadhesive‐Integrated 3D‐Printed Multilayer Scaffolds Secure a Mechanically‐Stable Osteoimmune Niche for Enhanced Bone Augmentation

Advanced Science, EarlyView.
A 3D‑printed multilayer adhesive scaffold, firmly anchored to bone defects by simple finger pressing, suppresses micromotion and secures mechanical stability of the osteogenic niche. This stabilization likely contributes to the enhanced bone augmentation by fostering a pro‑regenerative mechano‐immune profile—characterized by M2‑like macrophage ...
Delu Zhao, Qiuyi Li, Lingyun Wang, Chongao Zhang, Yutian Cheng, Shuang Liu, Fulan Wei, Zheqin Dong   +7 more
wiley   +1 more source

Optimization of graded porous acoustic absorbers based on triply periodic minimal surfaces

Materials & Design
The acoustic absorption of a porous structure within a specific frequency range can be tuned by varying its porosity along its thickness. In this work, triply periodic minimal surfaces (TPMS) are employed to generate graded porous structures, where the ...
Xueying Guan, Elke Deckers, Hao Dong, Maarten Hornikx, Jieun Yang   +4 more
doaj   +1 more source