Results 61 to 70 of about 2,238,792 (224)

Thermal characterization of 3D-Printed lattices based on triply periodic minimal surfaces embedded with organic phase change material

open access: yesCase Studies in Thermal Engineering, 2021
Owing to their high latent heat of fusion and thermal stability, organic phase change materials (PCMs) are lucrative candidates for utilization in latent heat thermal energy storage systems (LHTES).
Zahid Ahmed Qureshi   +5 more
doaj   +1 more source

YAP1‐Driven Pathogenic Fibro‐Adipogenic Progenitors Secrete IL‐6 and FGF21 to Mediate Muscle‐Bone Crosstalk and Promote Bone Loss

open access: yesAdvanced Science, EarlyView.
Fibro‐adipogenic progenitors (FAPs) in atrophic muscle undergo YAP1‐driven pathogenic activation, secreting IL‐6 and FGF21 as bone‐catabolic myokines that mediate muscle‐bone crosstalk and promote bone loss. Genetic or pharmacological targeting of this YAP1‐FAP‐myokine axis rescues skeletal deterioration, identifying FAP‐derived myokines as therapeutic
Xiaoyu Cai   +16 more
wiley   +1 more source

Exploration of the orientational-dependent fatigue response of triply periodic minimal surface cellular structures: A numerical study [PDF]

open access: yes
Recently, Triply Periodic Minimal Surface (TPMS)-based lattices have received significant attraction in structural applications across a variety of engineering sectors, including automobile, aerospace, and biomedical, owing to their improved mechanical ...
CHEMISKY, Yves   +2 more
core   +1 more source

On the compressive and flexural properties of additively manufactured 316 L stainless steel sheet-based spinodal, stochastic and periodic TPMS cellular metamaterials

open access: yesMaterials & Design
The mechanical properties of cellular structures derived from spinodal decomposition and triply periodic minimal surfaces (TPMSs) are gaining interest for lightweight metamaterials, particularly with advances in additive manufacturing.
Hafiz M. Abubaker   +4 more
doaj   +1 more source

Nanoparticle‐Mediated TIPE1 mRNA Delivery Enhances Paclitaxel Sensitivity in Triple‐Negative Breast Cancer by Modulating RAB7A Ubiquitination‐Associated Stability and Autophagy

open access: yesAdvanced Science, EarlyView.
TIPE1m NPs nanoparticles restore TIPE1 expression, promote RAB7A ubiquitination and degradation, suppress autophagic flux, and resensitize paclitaxel‐resistant triple‐negative breast cancer to therapy. ABSTRACT Acquired paclitaxel (PTX) resistance remains a major obstacle in triple‐negative breast cancer (TNBC) treatment.
Wei Hu   +9 more
wiley   +1 more source

Bioadhesive‐Integrated 3D‐Printed Multilayer Scaffolds Secure a Mechanically‐Stable Osteoimmune Niche for Enhanced Bone Augmentation

open access: yesAdvanced Science, EarlyView.
A 3D‑printed multilayer adhesive scaffold, firmly anchored to bone defects by simple finger pressing, suppresses micromotion and secures mechanical stability of the osteogenic niche. This stabilization likely contributes to the enhanced bone augmentation by fostering a pro‑regenerative mechano‐immune profile—characterized by M2‑like macrophage ...
Delu Zhao   +7 more
wiley   +1 more source

Elastically isotropic auxetic and zero-Poisson’s ratio TPMS-based metamaterials

open access: yesVirtual and Physical Prototyping
Triply periodic minimal surfaces (TPMS) can create high performance, multifunctional, metamaterials that are lightweight and have highly tailorable properties. However, such TPMS structures are typically highly anisotropic in terms of stiffness, which is
Stephen Daynes
doaj   +1 more source

Printable Piezoresistive Hybrid Hydrogels Based on 2D MoS2 for Flexible Pulse Sensing

open access: yesAdvanced Science, EarlyView.
Hybrid 1T‐MoS2‐based hydrogels are engineered through UV curing and 3D printing to achieve tunable electromechanical properties for wearable sensing. These soft architectures enhance mechanical stability and reproducible piezoresistive responses within the physiological pressure range.
Jenny Flores   +18 more
wiley   +1 more source

Dual‐line Genome‐scale CRISPR Screening Enables Robust Target Gene Discovery

open access: yesAdvanced Science, EarlyView.
A species‐optimized CRISPR platform integrates efficient piggyBac delivery, genome‐scale sgRNA libraries, and parallel screening in two independently engineered Bactrocera dorsalis Cas9 cell lines. Cross‐line consensus analysis filters line‐specific effects, enriches candidates with reproducible in vivo phenotypes, and reveals conserved, species ...
Ziniu Li   +9 more
wiley   +1 more source

Review of Triply Periodic Minimal Surface (TPMS) Structures for Cooling Heat Sinks

open access: yesEnergies
This review paper deals with Triply Periodic Minimal Surfaces (TPMS) and lattice structures as a new generation of heat exchangers. Especially, their manufacturing is becoming feasible with technological progress. While some intricate structures are fabricated, challenges persist concerning manufacturing limitations, cost-effectiveness, and performance
Khaoula Amara   +2 more
openaire   +1 more source

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