Results 81 to 90 of about 807 (197)

Regression Analysis of Triply Periodic Minimal Surface (TPMS) Models to Achieve Multi-Objective Optimization

Applied Sciences
Freshwater scarcity demands innovative solutions, and Atmospheric Water Generation (AWG) technology offers a promising approach. This study applies a data-driven optimization methodology to enhance AWG efficiency by improving condensation surface design using Triply Periodic Minimal Surface (TPMS) structures. Five TPMS types (Gyroid, Diamond, Lidinoid,
Fatema Tuz Zohra, Bahram Asiabanpour
openaire   +2 more sources

Dehydrocostus Lactone Suppresses Hepatocellular Carcinoma by Inhibiting Protein Tyrosine Kinase‐7 Mediated β‐Catenin Signaling

Phytotherapy Research, EarlyView.
Schematic summary of the experimentally supported mechanism of DHL in hepatocellular carcinoma. Dehydrocostus lactone (DHL), a sesquiterpene lactone derived from Aucklandia lappa, directly engages protein tyrosine kinase 7 (PTK7), as supported by molecular docking, CETSA, and DARTS assays.
Xiwen Fan, Junhui Li, Yu Qiao, Yuwen Zhong, Xuecheng Ge, Yaoshuai Zhang, Zishu Wang, Feng Qian, Weixin Ren   +8 more
wiley   +1 more source

Multifunctional Nanodiamond Conjugate With a Tumor‐Specific EGFR‐Targeting Peptide and Photoactivated CO Release for Improved Therapeutic Efficacy in Head and Neck Cancers

Small, EarlyView.
A multifunctional nanodiamond conjugate carrying a blue light‐activated carbon monoxide‐releasing molecule and an EGFR‐targeting peptide enables efficient, targeted CO delivery in vitro and in vivo. Upon photoactivation, the particles induce cancer‐specific cytotoxicity and significantly suppress tumor growth and lymph node metastasis in a head and ...
Harsh Nitin Dongre, Elisabeth Mayerhoefer, Julia Puck, Himalaya Parajuli, Lorena Larios Salazar, Paul Johan Høl, Ridhima Das, Patrick Roth, Christian Arvei Moen, Ulrich Schatzschneider, Line Bjørge, Daniela Elena Costea, Anke Krueger   +12 more
wiley   +1 more source

Thermo-hydraulic performance of uniform and hybrid Triply Periodic Minimal Surfaces (TPMS) heat exchangers

Proceedings of the Holistic Innovation in Additive Manufacturing (HI-AM) Conference
Triply Periodic Minimal Surfaces (TPMS) geometries are remarkable solutions for achieving optimal heat transfer performance in industries where space-efficient cooling solutions are required. Utilizing these additively manufactured geometries in Heat Exchanger (HX) applications involves a trade-off between maximizing heat transfer and minimizing ...
Armin Hassanirad, Collins Chike Kwasi-Effah, Osezua Ibhadode   +2 more
openaire   +1 more source

Geometry‐Encoded Programmable Mechanics in Single‐Material Dual‐Phase Metamaterials

Small, EarlyView.
Inspired by the unique soft‐hard heterogeneous architecture of nacre, this study proposes a novel class of dual‐phase (DP) metamaterials. The DP metamaterials exhibit programmable nonlinear mechanical responses, tailored failure processes, and enhanced energy absorption by systematically varying the spatial coding patterns of soft‐hard unit cells ...
Miao Zhao, Na Qiu, Xuhui Zhang, Bei Peng, Zhi Zeng, Xinwei Li, Qing Li   +6 more
wiley   +1 more source

Oxidative stress‐driven metabolic reprogramming defines two subtypes of cutaneous melanoma

VIEW, EarlyView.
Cutaneous melanoma exhibits substantial molecular heterogeneity, and metabolic reprogramming may contribute to differences in tumor behavior and treatment response. In this study, we integrated multi‐omics data from SKCM cohorts to identify two metabolism‐associated subtypes with distinct oxidative stress profiles, immune microenvironments, prognostic ...
Qikun Gao, Ziyi Liu, Ying Xu
wiley   +1 more source

Investigation of functionally graded TPMS structures fabricated by additive manufacturing

Materials & Design, 2019
Triply periodic minimal surfaces (TPMS), which have zero mean curvature and large surface areas, are discussed in this paper. Two TPMS structures, the Schwarz Primitive (P) and Gyroid, were designed with both uniform and graded density and fabricated ...
Shixiang Yu, Jinxing Sun, Jiaming Bai
doaj   +1 more source

RAB4A acts as a negative feedback regulator of extracellular vesicle secretion during TGF‐β signaling

The FEBS Journal, EarlyView.
TGF‐β signaling regulates extracellular vesicle (EV) release in cancer cells by modulating the expression and activity of genes associated with EV biogenesis. The TGF‐β‐induced upregulation of RAB4A expression facilitates fast endosomal recycling, a process that limits the fusion of multivesicular bodies with the plasma membrane and EV secretion. Hence,
Dorival Mendes Rodrigues‐Junior, Maria Anastasia Doumani, Hao Fu, Jelle van den Bor, Olof Idevall‐Hagren, Aristidis Moustakas   +5 more
wiley   +1 more source

Influence of degree of conversion on the cytotoxicity of 3D‐printed denture base resins. A scoping review

Journal of Prosthodontics, EarlyView.
Abstract Purpose Evidence regarding the cytotoxicity of 3D‐printed denture base resins and the role of degree of conversion remains limited and heterogeneous. Therefore, this scoping review aimed to map existing in vitro evidence and explore how degree of conversion and post‐processing factors are reported in relation to biological outcomes.
Nathan Felipini Ferreira, João Pedro Justino de Oliveira Limírio, Ana Beatriz de Souza Albergardi, Emilia de Paula, Sebastian Daniel Aguayo Paul, Jéssica Marcela de Luna Gomes   +5 more
wiley   +1 more source

Curvature modulation of TPMS-based lattices: from geometric design to enhanced mechanical responses

Virtual and Physical Prototyping
The performance optimisation of Triply Periodic Minimal Surfaces (TPMS) structures currently faces a critical bottleneck involving a transition from a density-driven to a geometry-driven paradigm.
Ruobing Liao, Zhi Guo, Jichao Liu, Zihong Mai, Xiangyu Ma, Mohd Zamir Pakhuruddin, Hang Zhang, Chengjun Luo, Liang Zhu, Kun Li, Huajun Cao   +10 more
doaj   +1 more source