Results 71 to 80 of about 807 (197)

Dual‐line Genome‐scale CRISPR Screening Enables Robust Target Gene Discovery

Advanced Science, EarlyView.
A species‐optimized CRISPR platform integrates efficient piggyBac delivery, genome‐scale sgRNA libraries, and parallel screening in two independently engineered Bactrocera dorsalis Cas9 cell lines. Cross‐line consensus analysis filters line‐specific effects, enriches candidates with reproducible in vivo phenotypes, and reveals conserved, species ...
Ziniu Li, Jiao Qiao, Qiuyuan Zhang, Peipei Liu, Chenjun Zheng, Qi Zhou, Mengqi Ji, Zhihui Zhu, Xiaoxue Li, Hongyu Zhang   +9 more
wiley   +1 more source

Deep Learning‐Driven Discovery and Engineering of an Efficient PETase for Depolymerization and Detoxification of PET Microplastics Under Physiological Conditions

Advanced Science, EarlyView.
A deep learning–driven pipeline mining 246 million protein sequences uncovers AhPETase, an evolutionarily distinct PET hydrolase. Engineered variant AhPETaseM1 degrades post‐consumer PET microplastics under physiological conditions and reverses microplasticinduced cytotoxicity in human lung and colon cells, establishing enzymatic microplastic ...
Yuxuan Wang, Shijie He, Yuheng Chang, Sheng Mao, Jianan Canal Li, Binbin Chen, Hongxun Gao, Mingchun Xu, Chenxu Liu, Yajie Wang   +9 more
wiley   +1 more source

On quantifying dynamic behavior of architected metal/polymer TPMS/lattices-based interpenetrating phase composites

Scientific Reports
This article presents the numerical analysis of architected metal/polymer-based interpenetrating phase composites (IPCs) to study their effective mechanical properties and dynamic behavior using finite element (FE) simulation. In this, we considered four
K. B. Shingare, Andreas Schiffer, Kin Liao   +2 more
doaj   +1 more source

Tuneable mechanical performance and reusability of 4D-printed heterogeneous metamaterials using shape memory biomass-derived polymer

Virtual and Physical Prototyping
Herein, hybrid triply periodic minimal surfaces (TPMS) metamaterials were structurally designed and additively manufactured via 4D printing using a biomass-derived shape memory polymer.
Lin Sang, Wenyang Wu, Yutong Yao, Xufeng Dong, Huanyue Zhang, Hao Zhang   +5 more
doaj   +1 more source

Innovative Metal‐Modified Resins via 3D Printing of Triply Periodic Minimal Surface Structures

Journal of Applied Polymer Science, EarlyView.
A solvent‐free dual‐monomer strategy enables the direct 3D printing of nickel‐containing TPMS catalyst supports with uniform metal distribution and preserved open‐channel architecture. The resulting structures exhibit excellent printability, thermal and water stability, and enhanced flexibility, offering a promising platform for next‐generation ...
Erika Blanzeanu, Derniza‐Elena Cozorici, Ionut‐Cristian Radu, Marian N. Verziu, Bogdan S. Vasile, Rafael Luque, Catalin Zaharia   +6 more
wiley   +1 more source

Design of TPMS-based Uniform and Hybrid Graded Lattice Structures: A Fluid Flow Analysis [PDF]

MATEC Web of Conferences
Each year, more than four million people around the world undergo bone grafts and prosthesis transplants to treat bone defects and injuries by repairing and/or replacing native bone.
Rajkumar, Ramkumar Janakarajan, Balani Kantesh   +2 more
doaj   +1 more source

Optimization of 3D‐Printed Structured Packings—Current State and Future Developments

Chemie Ingenieur Technik, EarlyView.
This paper gives an overview about structured packing development for distillation, surveying heuristic development cycles, computational fluid dynamics simulations, and additive manufacturing techniques. The emerging application of shape optimization to improve packings is emphasized, and its benefits, impact, and limitations are discussed.
Dennis Stucke, Sebastian Blauth, Christian Leithäuser, Thomas Grützner   +3 more
wiley   +1 more source

Data-driven design of isotropic and high-stiffness TPMS-based aperiodicity-induced architected material (TAAM)

Materials & Design
For their excellent stiffness-to-weight characteristics, triply periodic minimal surfaces (TPMS) are widely adopted in architected materials. However, their geometric regularity often leads to elastic anisotropy, limiting their effectiveness under ...
Minwoo Park, Junheui Jo, Seunghwa Ryu
doaj   +1 more source

Smart Functional Hydrogels: Emerging Platforms for Thermal and Electrochemical Energy Harvesting and Conversion Systems

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
The hydrogel exhibits versatile functions, including efficient thermogalvanic conversion under a temperature difference, and acting as a cooling layer/forming a thermally conductive nanoactive composite for thermovoltaic conversion. Additionally, its self‐healing and self‐powered flexibility play a key role in energy storage systems. The growing demand 
Eunah Kang
wiley   +1 more source

Triboelectric nanogenerators for vehicle intelligent cockpits

FlexMat, EarlyView.
Converting mechanical stimuli from drivers and vehicle motion into electrical signals, triboelectric nanogenerators provide promising interfaces toward passive, flexible, distributed and intelligent sensing for next‐generation automotive cockpits to support three core functional dimensions: driver state monitoring, vehicle state monitoring, and human ...
Haiqiu Tan, Shiquan Lü, Xiangwei Meng, Huiying Zhang, Wenxing Zhang, Dongxian Sun, Xiao Lu, Lei Wang, Haodong Zhang, William W. Yu   +9 more
wiley   +1 more source