Results 41 to 50 of about 7,752 (219)

Headache disorders among Indigenous communities: A scoping review undertaken with knowledge keeper guidance

Headache: The Journal of Head and Face Pain, EarlyView.
Abstract Objective We performed a scoping review of literature on headache etiology, classification, prevalence, and treatment in Indigenous communities in Canada, the United States, Australia, and New Zealand. Background In the United States, analysis of national prevalence indicates that Indigenous Americans lead all other racial/ethnic groups in ...
Maia Kelly, Candice M. Todd, Ojistoh Kahnawahere Horn, Emily Simmonds, Diane Longboat, Cynthia White, Suvendrini Lena   +6 more
wiley   +1 more source

Classification and some properties of triptans [PDF]

, 2013
Triptans are a group of tryptamine-based drugs used in the acute treatment of migraine headaches. Structurally related to the neurotransmitter serotonin, triptans acts by selectively binding to serotonin type-1D receptors. The present paper submitted the
Antal, Irуna
core  

The putative proton-coupled organic cation antiporter is involved in uptake of triptans into human brain capillary endothelial cells

Fluids and Barriers of the CNS
Background Triptans are anti-migraine drugs with a potential central site of action. However, it is not known to what extent triptans cross the blood–brain barrier (BBB).
Nana Svane, Alberte Bay Villekjær Pedersen, Anne Rodenberg, Burak Ozgür, Lasse Saaby, Christoffer Bundgaard, Mie Kristensen, Peer Tfelt-Hansen, Birger Brodin   +8 more
doaj   +1 more source

Pregnancy outcomes following exposure to galcanezumab: Analysis of cases from the galcanezumab clinical trials and postmarketing database

Headache: The Journal of Head and Face Pain, EarlyView.
Abstract Objective This study was conducted to describe pregnancy outcomes reported following maternal or paternal exposure to galcanezumab in clinical trials and postmarketing surveillance. Background Galcanezumab is a calcitonin gene‐related peptide‐inhibiting monoclonal antibody indicated for the preventive treatment of migraine.
Irene Boz, Jan Lewis Brandes, Christopher Robinson, Maria Fernanda Scantamburlo Fernandes, Sarah Lipsius, LaRonda Morford, Enemona Emmanuel Adaji, Anaclara Prada Jardim, Holland C. Detke   +8 more
wiley   +1 more source

The MIND study: Design, feasibility, and baseline characteristics of a smartphone‐based migraine cohort

Headache: The Journal of Head and Face Pain, EarlyView.
Abstract Objectives/Background Our objective was to describe the design, feasibility, and baseline characteristics of the Migraine Impact on Neurocognitive Dynamics study, a 30‐day smartphone‐based, prospective, decentralized, observational cohort study evaluating high‐frequency assessment of cognition and symptoms in adults with migraine.
Babak Khorsand, Devin Teichrow, Richard B. Lipton, Ali Ezzati   +3 more
wiley   +1 more source

Pharmacoepidemiology of triptans in a headache centre

, 2010
Aims: The aims of this survey were: (i) to examine the pharmacoepidemiology of triptans in a headache centre; (ii) tocompare the characteristics of patients who continued to take triptans with those of patients who had discontinued them.Methods: We ...
STERNIERI, Emilio, FERRARI, Anna, SPACCAPELO, Luca   +2 more
core   +1 more source

Beyond headache frequency: How acute treatment response shapes migraine‐related disability—Insights from a joint stratification framework: A cross‐sectional study

Headache: The Journal of Head and Face Pain, EarlyView.
Abstract Objectives/Background The aim of this study was to examine whether joint profiling of headache frequency and acute treatment response identifies clinically meaningful patient subgroups with different disability burden and treatment needs, and whether per‐attack acute treatment response provides disability‐relevant information beyond monthly ...
Xiaonuo Xu, Hui Li, Xin Liang, Xiaoping Fan, Ge Tan, Xiangmin Yu, Xin Li, Liang Dong, Jiying Zhou   +8 more
wiley   +1 more source

Gene polymorphisms involved in triptans pharmacokinetics and pharmacodynamics in migraine therapy

, 2010
Areas covered in this review: The review summarises the results of association studies between polymorphisms in genes involved in the kinetics and dynamics of triptans, and clinical response to them in migraineurs. What the reader will gain: A summary of
Paolo Martelletti, MARTELLETTI, Paolo, Noemi Lala, MISSORI, Serena, Giovanna Gentile, Maurizio Simmaco, LALA, NOEMI, BORRO, Marina, GENTILE, Giovanna, SIMMACO, Maurizio, Marina Borro, Serena Missori   +11 more
core   +1 more source

Review of frovatriptan in the treatment of migraine

Neuropsychiatric Disease and Treatment, 2008
Leslie KelmanHeadache Center of Atlanta, Atlanta, GA, USAAbstract: Triptans are recommended for the acute treatment of moderate to severe migraine or failure to respond to other acute migraine treatments.
Leslie Kelman
doaj  

Real‐world diagnosis and treatment of individuals with migraine in the United States: The Migraine Insights in Diagnosis and Treatment (MIND) study

Headache: The Journal of Head and Face Pain, EarlyView.
Abstract Objective The objective of this study was to describe the real‐world diagnosis and treatment patterns of individuals newly diagnosed with migraine in the United States (US). Background Over 10% of adults in the US are living with migraine.
Fred Cohen, Vincent Martin, Avani Patel, Shelby L. Corman, Katie B. Tellor, Meghan Fajardo, D. Cortney Hayflinger, Simon Dagenais   +7 more
wiley   +1 more source