Background. Migraine is a frequent neurological disorder affecting mostly women in the childbearing age. It is influenced by fluctuation of female hormones, especially estrogen levels. Objectives.
Andreea Elena Dumitru +4 more
doaj +1 more source
Update on medication-overuse headache and its treatment [PDF]
OPINION STATEMENT: Medication-overuse headache-i.e., a too-frequent consumption of acute headache medications leading to increased headache frequency and reduced effectiveness of acute and preventive treatments-is a serious medical condition whose ...
Giamberardino MA +2 more
core +1 more source
The effect of weight, body mass index, age, sex, and race on plasma concentrations of subcutaneous sumatriptan: a pooled analysis. [PDF]
Objective/backgroundFactors such as body size (weight and body mass index [BMI]), age, sex, and race might influence the clinical response to sumatriptan. We evaluated the impact of these covariates on the plasma concentration (Cp) profile of sumatriptan
Fisher, Dennis M +3 more
core +3 more sources
Calcitonin gene-related peptide receptor antagonist BIBN 4096 BS for the acute treatment of migraine [PDF]
Background: Calcitonin gene–related peptide (CGRP) may have a causative role in migraine. We therefore hypothesized that a CGRP-receptor antagonist might be effective in the treatment of migraine attacks.
Diener, H.-C. +7 more
core +1 more source
Advances in Acute Migraine Therapy: Triptans Compared with CGRP Receptor Antagonists
Introduction and purpose: Migraine is one of the most common and disabling neurological disorders. Attacks significantly decrease quality of life and daily functioning; therefore, effective treatment is crucial.
Michał Chodor +2 more
doaj +1 more source
Triptans in the acute treatment of migraine: A systematic review and network meta-analysis. [PDF]
BACKGROUND: Although triptans are widely used in the acute management of migraine, there is uncertainty around the comparative efficacy of triptans among each other and vs non-triptan migraine treatments.
Ades +25 more
core +1 more source
This study mimics clinical patch testing for the diagnosis of allergic contact dermatitis, by application of patch test preparations of fragrance terpenes to ex vivo human skin samples. The study investigates the penetration of linalool hydroperoxide and limonene hydroperoxide in skin, alongside an analysis of the lipid‐modifying effects of the patch ...
Aoife Clancy +3 more
wiley +1 more source
Progress in the Treatment of Migraine Attacks: From Traditional Approaches to Eptinezumab
Migraine is the second cause of disability and of lost years of healthy life worldwide. Migraine is characterized by recurrent headache attacks and accompanying disabling symptoms lasting 4–48 h.
Damiana Scuteri, Giacinto Bagetta
doaj +1 more source
Assessment of acute headache in adults - what the general physician needs to know. [PDF]
Headache is common. Up to 5% of attendances to emergency departments and acute medical units are due to headache. Headache is classified as either primary (eg migraine, cluster headache) or secondary to another cause (eg meningitis, subarachnoid ...
Agrawal +9 more
core +1 more source
Effectiveness and acceptability of oral migraine preventives: A prospective, observational study
Abstract Objective To explore the adherence, effectiveness, safety, tolerability, and acceptability of frequently used oral migraine preventive drugs in a real‐world setting. Background Oral migraine preventives are previously mainly explored in randomized controlled trials, whereas real‐world data on treatment outcomes remain limited. Methods MigriNor
Hedda S. Riise +13 more
wiley +1 more source

