Results 11 to 20 of about 7,752 (219)
Expert Review of Neurotherapeutics, 2009 The migraine-specific triptans have revolutionized the treatment of migraine and are currently the drugs of choice to treat a migraine attack in progress. Over the past 15 years, triptans were released in rapid succession, with each one demonstrating some specific pharmacokinetic properties that may be translated into clinical advantages.
Bigal, Marcelo E. +2 more
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Triptans in treatment of migraine
Медицинский совет, 2015 Migraine is one of the most common neurological disease that manifests itself in severe headache attacks. It is one of the most widespread causes of disability in young and middle-aged people.
V. A. Golovacheva, V. A. Parfyonov
doaj +2 more sources
Cardiovascular safety of triptans in the acute treatment of migraine
Медицинский совет, 2014 The article highlights the issues of safety when using triptans in the treatment of migraine and the risks of cardiovascular complications. Results of a large prospective population study are provided demonstrating that triptans in patients with migraine
G. R. Tabeyeva
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Principles of effective use of triptans in relieving migraine attack
Медицинский совет, 2013 The article tells about the pathogenetic mechanisms of action of triptans, principles of prescription and guidelines for relieving migraine.
V. V. Osipova
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Pain Research and Management, 2000 In the past 10 years, there have been great advances in the understanding of the pathophysiology of the migraine. This has been due in part to the realization that the migraine attack can be blocked by activating the serotonin receptor, namely the 5 ...
Marek J Gawel
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Therapeutic Drug Monitoring, 2008 The triptans are a class of tryptamine-based drugs indicated for in the treatment of migraine headaches. The triptans act as serotonin (5-hydroxytriptamine) (5-HT) agonists by binding to various serotonin receptors, causing vasoconstriction and neuronal inhibition to alleviate migraines.
Offie P, Soldin +2 more
openaire +2 more sources
Use of triptans during pregnancy? With caution!
, 2021 International audienceWe report cases, registered in the French national pharmacovigilance database, of fetal death and intrauterine growth retardation in women exposed to triptans during pregnancy. Triptans have vasoconstrictive properties and we wonder
Damase-Michel, Christine +5 more
core +1 more source
New Approaches to Shifting the Migraine Treatment Paradigm
Frontiers in Pain Research, 2022 The standard of care paradigm for migraine treatment has been based almost exclusively on approaches that grew out of the happenstance use of market pharmaceuticals.
Brian Johnson, Frederick G. Freitag
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Journal of Primary Care & Community Health, 2020 Introduction: Triptans, the most commonly prescribed acute treatments for migraine attacks are, per FDA labeling, contraindicated in cardiovascular (CV) disease patients and have warnings and precautions for those with CV risk factors.
David W. Dodick +11 more
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Canadian Journal of Pain, 2022 Background Though chronic pain is widespread, affecting about one-fifth of the world’s population, its impacts are disproportionately felt across the population according to socioeconomic determinants such as education and income.
Nicole Atkins, Karim Mukhida
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