Results 1 to 10 of about 50,090 (196)

Triterpenes in breast cancer: a systematic review of preclinical evidence in rodents [PDF]

Frontiers in Pharmacology
IntroductionBreast cancer poses a significant health problem for women worldwide due to late-stage diagnosis, toxicity of standard therapy and drug resistance.
Alexandra Prodea, Alexandra Prodea, Andreea Munteanu, Andreea Munteanu, Mihaela Jorgovan, Mihaela Jorgovan, Oana Batrina, Oana Batrina, Marius Mioc, Marius Mioc, Irina Soica, Cristina Trandafirescu, Cristina Trandafirescu, Codruta Soica, Codruta Soica   +14 more
doaj   +2 more sources

Chemical constituents isolated from stems of Maesa membranacea

Vietnam Journal of Science, Technology and Engineering, 2022
Maesa membranacea A. DC. (Myrsinaceae) has been traditionally used for the treatment of fever and hepatitis. The phytochemical investigation of Maesa membranacea stems has led to the isolation of six compounds including kaempferol (1), (-)-epicatechin ...
Nguyen Thanh Le, Huu Giap Tran, Thi Kim Oanh Vu, Thuy Duong Pham, Ngoc Thuc Dinh, Anna Stojakowska, Bich Ngan Truong   +6 more
doaj   +1 more source

Characterization of Triterpene Saponin Glycyrrhizin Transport by Glycyrrhiza glabra

Plants, 2022
Glycyrrhizin (GL), a triterpene compound produced by Glycyrrhiza species, is a crucial pharmacologically active component of crude drugs. In contrast to the biosynthesis of GL in plants, little is known about GL transport and accumulation in plants.
Kakuki Kato, Asako Horiba, Hiroaki Hayashi, Hajime Mizukami, Kazuyoshi Terasaka   +4 more
doaj   +1 more source

Interference between ER stress-related bZIP-type and jasmonate-inducible bHLH-type transcription factors in the regulation of triterpene saponin biosynthesis in Medicago truncatula

Frontiers in Plant Science, 2022
Triterpene saponins (TS) are a structurally diverse group of metabolites that are widely distributed in plants. They primarily serve as defense compounds and their production is often triggered by biotic stresses through signaling cascades that are ...
Bianca Ribeiro, Bianca Ribeiro, Marie-Laure Erffelinck, Marie-Laure Erffelinck, Elia Lacchini, Elia Lacchini, Evi Ceulemans, Evi Ceulemans, Maite Colinas, Maite Colinas, Clara Williams, Clara Williams, Evelien Van Hamme, Rebecca De Clercq, Rebecca De Clercq, Maria Perassolo, Maria Perassolo, Maria Perassolo, Maria Perassolo, Alain Goossens, Alain Goossens   +20 more
doaj   +1 more source

A seed-specific regulator of triterpene saponin biosynthesis in Medicago truncatula [PDF]

, 2020
Plants produce a vast array of defense compounds to protect themselves from pathogen attack or herbivore predation. Saponins are a specific class of defense compounds comprising bioactive glycosides with a steroidal or triterpenoid aglycone backbone. The
Arendt, Philipp, Bicalho, Keylla, Buitink, Julia, Calegario, Gabriela, Ceulemans, Evi, Goossens, Alain, Gryffroy, Lore, Lacchini, Elia, Mertens, Jan, Pollier, Jacob, Ribeiro, Bianca, Vanden Bossche, Robin   +11 more
core   +2 more sources

Boswellia serrata Preserves Intestinal Epithelial Barrier from Oxidative and Inflammatory Damage [PDF]

, 2015
Aminosalicylates, corticosteroids and immunosuppressants are currently the therapeutic choices in inflammatory bowel diseases (IBD), however, with limited remission and often serious side effects.
Brun, Paola, Caparrotta, Laura, Carrara, Maria, Castagliuolo, Ignazio, Catanzaro, Daniela, Dall'Acqua, Stefano, Giron, Maria Cecilia, Montopoli, Monica, Orso, Genny, Ragazzi, Eugenio, Serena, Rancan   +10 more
core   +5 more sources

Acute and Chronic Effects of Green Oat (Avena sativa) Extract on Cognitive Function and Mood during a Laboratory Stressor in Healthy Adults: A Randomised, Double-Blind, Placebo-Controlled Study in Healthy Humans [PDF]

, 2020
Green oat (Avena sativa) extracts contain several groups of potentially psychoactive phytochemicals. Previous research has demonstrated improvements in cognitive function following a single dose of these extracts, but not following chronic ...
Bonnländer, Bernd, Forster, Joanne, Jackson, Philippa, Kennedy, David, Khan, Julie, Lang, Stefanie C., Pischel, Ivo, Wightman, Emma   +7 more
core   +2 more sources

First Evidence of Gastroprotection by Schinus molle: Roles of Nitric Oxide, Prostaglandins, and Sulfhydryls Groups in Its Mechanism of Action

Molecules, 2022
Schinus molle is a plant traditionally used in Mexico to treat gastric disorders. However, no scientific evidence has been reported on its gastroprotective effect. The aim of the current contribution was to conduct a bioassay-guided study on S.
María Elena Sánchez-Mendoza, Yaraset López-Lorenzo, Leticia Cruz-Antonio, Daniel Arrieta-Baez, Miranda Carolina Pérez-González, Jesús Arrieta   +5 more
doaj   +1 more source

Identification of early quassinoid biosynthesis in the invasive tree of heaven (Ailanthus altissima) confirms evolutionary origin from protolimonoids

Frontiers in Plant Science, 2022
The tree of heaven, Ailanthus altissima (MILL.) SWINGLE, is a globally invasive plant known to secrete allelopathic metabolites called quassinoids. Quassinoids are highly modified triterpenoids.
Ling Chuang, Shenyu Liu, Dave Biedermann, Jakob Franke, Jakob Franke   +4 more
doaj   +1 more source

Identification and characterization of an acyl-CoA:triterpene acyltransferase activity in rabbit and human tissues.

Journal of Lipid Research, 1991
Rabbit and human tissues contain substantial amounts of an unusual lipid, a fatty acid ester of a pentacyclic triterpene, that is a potent in vitro inhibitor of acyl-CoA:cholesterol acyltransferase (ACAT). A possible origin of the triterpene ester is via
I Tabas, N Beatini, LL Chen, WC Su, MS Puar, S Dugar, JW Clader   +6 more
doaj   +1 more source