Results 141 to 150 of about 46,021 (301)

Acanthospermum hispidum and Its Metabolite Stigmasterol Modulates Anti‐Inflammatory Antagonism of COX‐1 and TGF‐β

Chemistry &Biodiversity, Volume 23, Issue 1, January 2026.
This study evaluates the anti‐inflammatory effect of Acanthospermum hispidum (AH) leaves and confirms its traditional use on diseases linked to inflammation. AH ethanol extract presents a dose‐dependent increase in anti‐inflammatory activity on the different times examined (T30 – T150). Also, stigmasterol present in AH shows potent antagonist influence
Onome Mary Adeboye, Abimbola Sowemimo, Muyiwa Samuel Fageyinbo, Oluwasegun Adedokun, Abdul Basit, Opeyemi Joshua Olatunji, Epole Ngolle Ntungwe   +6 more
wiley   +1 more source

Acylation of Oleanolic Acid Oximes Effectively Improves Cytotoxic Activity in In Vitro Studies

Pharmaceutics
(1) Background: The aim of the presented work was to obtain a set of oleanolic acid derivatives with a high level of anticancer activity and a low level of toxicity by applying an economic method. Three types of oleanolic acid derivatives were obtained: (
Barbara Bednarczyk-Cwynar, Piotr Ruszkowski   +1 more
doaj   +1 more source

The State of Knowledge of the Primary and Secondary Metabolites of the Iris Genus

Chemistry &Biodiversity, Volume 23, Issue 1, January 2026.
The genus Iris L. (Iridaceae) comprises over 320 species, primarily found in the northern hemisphere. Iris species are important in horticulture, folklore and medicine, and contain a variety of primary and secondary metabolites with significant biological activity.
Olha Mykhailenko, Liudas Ivanauskas, Victoriya Georgiyants, Zigmantas Gudžinskas   +3 more
wiley   +1 more source

Nephroprotective Potential of Olea europaea Leaf Extract Against Combined Noise and Toluene‐Induced Oxidative and Histopathological Renal Injuries in Wistar Rats

Chemistry &Biodiversity, Volume 23, Issue 1, January 2026.
ABSTRACT Noise and toluene are environmental stressors that induce oxidative stress and inflammation, contributing to renal dysfunction. This study evaluated the protective effects of Olea europaea leaf extract (OeLE; 40 mg/kg/day) against combined noise‐ and toluene‐induced nephrotoxicity in Wistar rats.
Takoua Ben Attia, Mabrouk Horchani, Mariem Salhi, Zeineb Dhifallah, Meriem Ksentini, Hichem Ben Jannet, Abada Mhamdi   +6 more
wiley   +1 more source

Constituintes químicos de Luehea divaricata Mart. (Tiliaceae)

Química Nova, 2005
Chemical studies of the leaves of L. divaricata afforded 3beta-p-hydroxybenzoyl-tormentic acid, a triterpene with an ursene-type skeleton, a mixture whose main compound was an oleanene derivative, the maslinic acid, a C-glycoside flavone, vitexin and ...
Tanaka Júlio Cesar Akio, Silva Cleuza Conceição da, Dias Filho Benedito Prado, Nakamura Celso Vataru, Carvalho João Ernesto de, Foglio Mary Ann   +5 more
doaj  

Optimization of Extraction Process of Total Triterpenoids from Crataegus songarica by Response Surface Methodology and Its Purification Process

Shipin gongye ke-ji
In order to improve the high-value utilization of Crataegus songarica, the single factor experiment, orthogonal experiment and response surface design were used to optimize the extraction process of total triterpenes from Crataegus songarica by compound ...
Lin FENG, Shibo LUO, Guligena PIDAMAIMAITI, Yuanmeng LIU, Hongyan GAO   +4 more
doaj   +1 more source

Asiatic acid, a pentacyclic triterpene from Centella asiatica, is neuroprotective in a mouse model of focal cerebral ischemia [PDF]

, 2009
G. K. Rajanikant, Marie‐Claude Senut, Daniel Zemke, Jiangyong Min, Mark B. Frenkel, Eric Greenberg, Seong‐Woon Yu, Nick Ahn, John L. Goudreau, Mounzer Kassab, Kiran S. Panickar, Arshad Majid   +11 more
openalex   +1 more source

Bioactivity‐Guided Isolation of β‐Sitosterol From Terminalia glabrescens as a Potent Anti‐Zika Virus Agent

Chemistry &Biodiversity, Volume 23, Issue 1, January 2026.
ABSTRACT Zika virus (ZIKV) infection remains a global health concern due to its neurological complications and the lack of specific drugs or vaccines. This study investigated the anti‐ZIKV potential of an ethanolic extract from Terminalia glabrescens leaves.
Rosângela Santos Pereira, Priscilla Rodrigues Valadares Campana, Vivian Vasconcelos Costa, Vinícius Gonçalves Maltarollo, Rodrigo Maia de Pádua, José Hugo Sousa de Gomes, Grasiely Farias de Sousa, José Dias de Souza Filho, Daniele da Glória de Souza, Mauro Martins Teixeira, Fernão Castro Braga   +10 more
wiley   +1 more source

Lupane-type triterpenes and their anti-cancer activities against most common malignant tumors [PDF]

In recent times, a great deal of interest has been motivated on plant derived compounds known as nutraceuticals. These compounds exert important beneficial activities that improve people’s health status when are consumed regularly, and now they appear as
Cháirez-Ramírez, M. H., Gallegos-Infante, J. A., González-Laredo, R. F., Moreno-Jiménez, M. R., Rocha-Guzmán, N. E.   +4 more
core   +1 more source

A Flavonoid‐Rich Extract of Scoparia dulcis L. Exhibits Antiviral Activity against Herpes Virus Type 1

Chemistry &Biodiversity, Volume 23, Issue 1, January 2026.
ABSTRACT This study investigated the phytochemical profile, cytotoxicity, and anti‐herpetic activity of the hydroethanolic extract from Scoparia dulcis L. aerial parts. Mass spectrometry revealed the presence of 15 compounds. The extract showed low cytotoxicity in Vero cells, maintaining over 80% viability at concentrations up to 250 µg/mL.
Francisco Leandro Medeiros de Lucena Jales, Emerson Michell da Silva Siqueira, Renato Dantas‐Medeiros, Edilane Rodrigues Dantas de Araújo, Jovelina Samara Ferreira Alves, Hugo Alexandre de Oliveira Rocha, Norberto Peporine Lopes, Leandro de Santis Ferreira, Emanuella de Aragão Tavares, Silvana Maria Zucolotto   +9 more
wiley   +1 more source